Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Holly A. Wichman"'
Publikováno v:
Cells, Vol 13, Iss 7, p 585 (2024)
Recombination among different phages sometimes facilitates their ability to grow on new hosts. Protocols to direct the evolution of phage host range, as might be used in the application of phage therapy, would then benefit from including steps to ena
Externí odkaz:
https://doaj.org/article/a0271e3f8b964e79abf59746515a637a
Publikováno v:
Antibiotics, Vol 11, Iss 12, p 1709 (2022)
Background: The host ranges of individual phages tend to be narrow, yet many applications of phages would benefit from expanded host ranges. Empirical methods have been developed to direct the evolution of phages to attack new strains, but the method
Externí odkaz:
https://doaj.org/article/8bd0abbec73040078adf6e5a3341c137
Publikováno v:
Mobile DNA, Vol 10, Iss 1, Pp 1-11 (2019)
Abstract Background L1 retrotransposons have co-evolved with their mammalian hosts for the entire history of mammals and currently compose ~ 20% of a mammalian genome. B1 retrotransposons are dependent on L1 for retrotransposition and span the evolut
Externí odkaz:
https://doaj.org/article/100575ba763c4255a750445a0fb7b0af
Publikováno v:
Viruses, Vol 13, Iss 7, p 1389 (2021)
In microbial communities, viruses compete with each other for host cells to infect. As a consequence of competition for hosts, viruses evolve inhibitory mechanisms to suppress their competitors. One such mechanism is superinfection exclusion, in whic
Externí odkaz:
https://doaj.org/article/0f24b3963b0a4296b243a41077c8ab39
Publikováno v:
PeerJ, Vol 4, p e2227 (2016)
Parallelism is important because it reveals how inherently stochastic adaptation is. Even as we come to better understand evolutionary forces, stochasticity limits how well we can predict evolutionary outcomes. Here we sought to quantify parallelism
Externí odkaz:
https://doaj.org/article/f6ec732000be4607b5e7fe38a14ee42d
Autor:
Craig R. Miller, Erin L. Johnson, Aran Z. Burke, Kyle P. Martin, Tanya A. Miura, Holly A. Wichman, Celeste J. Brown, F. Marty Ytreberg
Publikováno v:
PeerJ, Vol 4, p e1674 (2016)
The 2014 Ebola virus (EBOV) outbreak in West Africa is the largest in recorded history and resulted in over 11,000 deaths. It is essential that strategies for treatment and containment be developed to avoid future epidemics of this magnitude. With th
Externí odkaz:
https://doaj.org/article/0768372ce1a8464a88ce2fd8b3139a04
Autor:
Celeste J Brown, Caleb J Quates, Christopher A Mirabzadeh, Craig R Miller, Holly A Wichman, Tanya A Miura, F Marty Ytreberg
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160410 (2016)
Since the recent devastating outbreak of Ebola virus disease in western Africa, there has been significant effort to understand the evolution of the deadly virus that caused the outbreak. There has been a considerable investment in sequencing Ebola v
Externí odkaz:
https://doaj.org/article/08d6494f738f43d69c55ed83d015af26
Publikováno v:
Mobile DNA, Vol 10, Iss 1, Pp 1-11 (2019)
Mobile DNA
Mobile DNA
Background L1 retrotransposons have co-evolved with their mammalian hosts for the entire history of mammals and currently compose ~ 20% of a mammalian genome. B1 retrotransposons are dependent on L1 for retrotransposition and span the evolutionary hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88461c80a8eccd719d59a054c3a79edb
http://link.springer.com/article/10.1186/s13100-019-0164-5
http://link.springer.com/article/10.1186/s13100-019-0164-5
Publikováno v:
PLoS Genetics, Vol 10, Iss 9, p e1004531 (2014)
Mammalian genomes comprise many active and fossilized retroelements. The obligate requirement for retroelement integration affords host genomes an opportunity to 'domesticate' retroelement genes for their own purpose, leading to important innovations
Externí odkaz:
https://doaj.org/article/4afacfdc604f4ebc93bb57a368d2735d
Publikováno v:
BioTechniques, Vol 29, Iss 6, Pp 1310-1316 (2000)
Many previous techniques for the isolation of endogenous retroelements such as LINE-1 retrotransposons have produced major sampling bias or required laborious procedures. These problems led to the isolation of only older elements in some cases. In ot
Externí odkaz:
https://doaj.org/article/19ac909dfdd742a08321e266d4930d27