Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Holly, Lindsay"'
Autor:
Sibo Zhao, Jia Li, Huiyuan Zhang, Lin Qi, Yuchen Du, Mari Kogiso, Frank K. Braun, Sophie Xiao, Yulun Huang, Jianfang Li, Wan-Yee Teo, Holly Lindsay, Patricia Baxter, Jack M. F. Su, Adekunle Adesina, Miklós Laczik, Paola Genevini, Anne-Clemence Veillard, Sol Schvartzman, Geoffrey Berguet, Shi-Rong Ding, Liping Du, Clifford Stephan, Jianhua Yang, Peter J. A. Davies, Xinyan Lu, Murali Chintagumpala, Donald William Parsons, Laszlo Perlaky, Yun-Fei Xia, Tsz-Kwong Man, Yun Huang, Deqiang Sun, Xiao-Nan Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
While recurrence is frequent in ependymoma, the underlying molecular mechanisms remain to be explored. Here, the authors investigate epigenetic, genetic and tumorigenic changes in 30 patient-matched repeated relapses over 13 years and identify distin
Externí odkaz:
https://doaj.org/article/67ce4ebc1c4e4e89b80aca05d5ec1d5f
Autor:
Pina, Armando A., Stoll, Ryan D., Holly, Lindsay E., Wynne, Henry, Chiapa, Amanda, Parker, Julia, Caterino, Linda, Tracy, Sarah J., Gonzales, Nancy A., Valdivieso, Alejandro
Publikováno v:
In Journal of Anxiety Disorders January 2023 93
Akademický článek
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Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 35, Iss , Pp 100861- (2023)
Medulloblastoma (MB) is the most common malignant central nervous system tumor of childhood, comprising a heterogenous group of tumors each with distinct biology, clinical behavior, and prognosis. Long-term survival remains unacceptable, and those wh
Externí odkaz:
https://doaj.org/article/ff173b7414bf426d9532398d55fe8224
Akademický článek
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Autor:
Mari Kogiso, Lin Qi, Yuchen Du, Frank K. Braun, Huiyuan Zhang, L. Frank Huang, Lei Guo, Yulun Huang, Wan-Yee Teo, Holly Lindsay, Sibo Zhao, Sarah G. Injac, Zhen Liu, Vidya Mehta, Diep Tran, Feng Li, Patricia A. Baxter, Jack M. Su, Laszlo Perlaky, D. Williams Parsons, Murali Chintagumpala, Adekunle Adesina, Yongcheng Song, Xiao-Nan Li
Publikováno v:
Translational Oncology, Vol 18, Iss , Pp 101368- (2022)
Clinical outcomes in patients with WHO grade II/III astrocytoma, oligodendroglioma or secondary glioblastoma remain poor. Isocitrate dehydrogenase 1 (IDH1) is mutated in > 70% of these tumors, making it an attractive therapeutic target. To determine
Externí odkaz:
https://doaj.org/article/caa882369eb742c39053f6d150c8b83b
Autor:
Yulun Huang, Lin Qi, Mari Kogiso, Yuchen Du, Frank K. Braun, Huiyuan Zhang, L. Frank Huang, Sophie Xiao, Wan‐Yee Teo, Holly Lindsay, Sibo Zhao, Patricia Baxter, Jack M. F. Su, Adekunle Adesina, Jianhua Yang, Sebastian Brabetz, Marcel Kool, Stefan M. Pfister, Murali Chintagumpala, Laszlo Perlaky, Zhong Wang, Youxin Zhou, Tsz‐Kwong Man, Xiao‐Nan Li
Publikováno v:
Advanced Science, Vol 8, Iss 23, Pp n/a-n/a (2021)
Abstract Diffuse invasion is the primary cause of treatment failure of glioblastoma (GBM). Previous studies on GBM invasion have long been forced to use the resected tumor mass cells. Here, a strategy to reliably isolate matching pairs of invasive (G
Externí odkaz:
https://doaj.org/article/d951663ff7d440bebd6494e2644f1aa3
Akademický článek
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Autor:
Xiao-Nan Li, Jodi A. Muscal, Stacey Berg, Mark G. Qian, Debra Liao, Adekunle M. Adesina, Patricia A. Baxter, Jack M. Su, Holly Lindsay, Sibo Zhao, Frank Y. Lin, Huiyuan Zhang, Yuchen Du, Linna Zhang, Sarah G. Injac, Frank K. Braun, Lin Qi, Mari Kogiso
Purpose: Pediatric glioblastoma multiforme (pGBM) is a highly aggressive tumor in need of novel therapies. Our objective was to demonstrate the therapeutic efficacy of MLN8237 (alisertib), an orally available selective inhibitor of Aurora A kinase (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add973a53fa03709cc14fba8c29ebe20
https://doi.org/10.1158/1078-0432.c.6526046
https://doi.org/10.1158/1078-0432.c.6526046
Autor:
Xiao-Nan Li, Jodi A. Muscal, Stacey Berg, Mark G. Qian, Debra Liao, Adekunle M. Adesina, Patricia A. Baxter, Jack M. Su, Holly Lindsay, Sibo Zhao, Frank Y. Lin, Huiyuan Zhang, Yuchen Du, Linna Zhang, Sarah G. Injac, Frank K. Braun, Lin Qi, Mari Kogiso
Supplementary Figure S1-S3 Figure S1. Anti-proliferative effects of MLN8237 on pGBM cell lines. Paired monolayer (Mono) and neurosphere (NS) of IC-4687GBM, IC-3752GBM and ICR0315GBM were seeded at 2,000 cells/well and exposed to MLN8237 (1 - 4,000 nM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf825c071ffe844120a4e784048d90e
https://doi.org/10.1158/1078-0432.22465520.v1
https://doi.org/10.1158/1078-0432.22465520.v1