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Autor:
Abdolreza, Yazdani, Holly, Bilton, Alyssa, Vito, Afaf R, Genady, Stephanie M, Rathmann, Zainab, Ahmad, Nancy, Janzen, Shannon, Czorny, Brian M, Zeglis, Lynn C, Francesconi, John F, Valliant
Publikováno v:
Journal of medicinal chemistry. 59(20)
A high yield synthesis of a novel, small molecule, bisphosphonate-modified trans-cyclooctene (TCO-BP, 2) that binds to regions of active bone metabolism and captures functionalized tetrazines in vivo, via the bioorthogonal inverse electron demand Die