Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Holloway DA"'
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5
Akademický článek
Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis.
Autor: Nair S; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Kumar SR; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Paidi VR; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Sistla R; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Kantheti D; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Polimera SR; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Thangavel S; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Mukherjee AJ; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Das M; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Bhide RS; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Pitts WJ; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Murugesan N; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Dudhgoankar S; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Nagar J; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Subramani S; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Mazumder D; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Carman JA; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Holloway DA; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Li X; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Fereshteh MP; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Ruepp S; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Palanisamy K; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Mariappan TT; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Maddi S; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Saxena A; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Elzinga P; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Chimalakonda A; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Ruan Q; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Ghosh K; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Bose S; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Sack J; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Yan C; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Kiefer SE; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Xie D; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Newitt JA; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Saravanakumar SP; Biocon Bristol Myers Squibb Research Center, Bangalore 560099, India., Rampulla RA; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Barrish JC; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Carter PH; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States., Hynes J Jr; Research & Development, Bristol Myers Squibb, Route 206 & Province Line Road, Princeton, New Jersey 08543, United States.
Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2020 Jun 10; Vol. 11 (7), pp. 1402-1409. Date of Electronic Publication: 2020 Jun 10 (Print Publication: 2020).
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6
Akademický článek
Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity.
Autor: Dudhgaonkar S; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Ranade S; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Nagar J; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Subramani S; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Prasad DS; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Karunanithi P; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Srivastava R; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Venkatesh K; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Selvam S; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Krishnamurthy P; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Mariappan TT; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Saxena A; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Fan L; Immunology Discovery, Bristol-Myers Squibb, Princeton, NJ 08543., Stetsko DK; Immunology Discovery, Bristol-Myers Squibb, Princeton, NJ 08543., Holloway DA; Immunology Discovery, Bristol-Myers Squibb, Princeton, NJ 08543., Li X; Lead Evaluation, Bristol-Myers Squibb, Princeton, NJ 08543., Zhu J; Translational Technologies, Bristol-Myers Squibb, Hopewell, NJ 08525., Yang WP; Translational Technologies, Bristol-Myers Squibb, Hopewell, NJ 08525., Ruepp S; Discovery Toxicology, Bristol-Myers Squibb, Princeton, NJ 08543; and., Nair S; Biocon Bristol-Myers Squibb Research Center, Bangalore 560099, India., Santella J; Discovery Chemistry, Bristol-Myers Squibb, Princeton, NJ 08543., Duncia J; Discovery Chemistry, Bristol-Myers Squibb, Princeton, NJ 08543., Hynes J; Discovery Chemistry, Bristol-Myers Squibb, Princeton, NJ 08543., McIntyre KW; Immunology Discovery, Bristol-Myers Squibb, Princeton, NJ 08543., Carman JA; Immunology Discovery, Bristol-Myers Squibb, Princeton, NJ 08543; julie.carman@bms.com.
Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2017 Feb 01; Vol. 198 (3), pp. 1308-1319. Date of Electronic Publication: 2016 Dec 21.
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7
Akademický článek
B cells from African American lupus patients exhibit an activated phenotype.
Autor: Menard LC; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Habte S; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Gonsiorek W; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Lee D; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Banas D; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Holloway DA; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Manjarrez-Orduno N; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Cunningham M; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Stetsko D; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Casano F; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Kansal S; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Davis PM; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Carman J; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Zhang CK; Immunoscience Translational Bioinformatics, Bristol-Myers Squibb Company, Pennington, New Jersey, USA., Abidi F; Division of Rheumatology, Northwell Health, Great Neck, New York, USA., Furie R; Division of Rheumatology, Northwell Health, Great Neck, New York, USA., Nadler SG; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA., Suchard SJ; Discovery Translational Sciences, Bristol-Myers Squibb Company, Princeton, New Jersey, USA.
Publikováno v: JCI insight [JCI Insight] 2016 Jun 16; Vol. 1 (9), pp. e87310. Date of Electronic Publication: 2016 Jun 16.
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8
Akademický článek
Improving the pharmacokinetic and CYP inhibition profiles of azaxanthene-based glucocorticoid receptor modulators-identification of (S)-5-(2-(9-fluoro-2-(4-(2-hydroxypropan-2-yl)phenyl)-5H-chromeno[2,3-b]pyridin-5-yl)-2-methylpropanamido)-N-(tetrahydro-2H-pyran-4-yl)-1,3,4-thiadiazole-2-carboxamide (BMS-341).
Autor: Yang MG; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Dhar TG; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Xiao Z; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Xiao HY; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Duan JJ; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Jiang B; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Galella MA; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Cunningham M; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Wang J; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Habte S; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Shuster D; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., McIntyre KW; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Carman J; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Holloway DA; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Somerville JE; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Nadler SG; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Salter-Cid L; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Barrish JC; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States., Weinstein DS; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2015 May 28; Vol. 58 (10), pp. 4278-90. Date of Electronic Publication: 2015 May 07.
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9
Akademický článek
Azaxanthene based selective glucocorticoid receptor modulators: design, synthesis, and pharmacological evaluation of (S)-4-(5-(1-((1,3,4-thiadiazol-2-yl)amino)-2-methyl-1-oxopropan-2-yl)-5H-chromeno[2,3-b]pyridin-2-yl)-2-fluoro-N,N-dimethylbenzamide (BMS-776532) and its methylene homologue (BMS-791826).
Autor: Weinstein DS; Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08543-4000, United States. David.Weinstein@bms.com, Gong H, Doweyko AM, Cunningham M, Habte S, Wang JH, Holloway DA, Burke C, Gao L, Guarino V, Carman J, Somerville JE, Shuster D, Salter-Cid L, Dodd JH, Nadler SG, Barrish JC
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2011 Oct 27; Vol. 54 (20), pp. 7318-33. Date of Electronic Publication: 2011 Oct 03.
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10
Akademický článek
Dimethyl-diphenyl-propanamide derivatives as nonsteroidal dissociated glucocorticoid receptor agonists.
Autor: Yang BV; Bristol-Myers Squibb Company, Research and Development, Princeton, New Jersey 08543-4000, United States., Weinstein DS, Doweyko LM, Gong H, Vaccaro W, Huynh T, Xiao HY, Doweyko AM, McKay L, Holloway DA, Somerville JE, Habte S, Cunningham M, McMahon M, Townsend R, Shuster D, Dodd JH, Nadler SG, Barrish JC
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2010 Dec 09; Vol. 53 (23), pp. 8241-51. Date of Electronic Publication: 2010 Nov 12.
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