Site-specific O-GlcNAcylation of progesterone receptor (PR) supports PR attenuation of interferon stimulated genes (ISGs) and tumor growth in breast cancer.

Autor: Saunders HI; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Holloran SM; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Trinca GM; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Artigues A; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Villar M; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Tinoco JC; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Dias WB; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA; Biophysics Institute Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Werner LR; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Chowanec EI; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Heard A; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Chalise P; Department of Biostatistics and Data Science, University of Kansas Medical Center, Kansas City, Kansas, USA., Slawson C; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA. Electronic address: cslawson@kumc.edu., Hagan CR; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, USA; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA. Electronic address: chagan@kumc.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2024 Nov; Vol. 300 (11), pp. 107886. Date of Electronic Publication: 2024 Oct 11.

Progesterone promotes immunomodulation and tumor development in the murine mammary gland.

Autor: Werner LR; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Gibson KA; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Goodman ML; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Helm DE; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Walter KR; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Holloran SM; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Trinca GM; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA., Hastings RC; Flow Cytometry Core Laboratory, University of Kansas Medical Center, Kansas City, Kansas, USA.; Department of Microbiology, Molecular Genetics, and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA., Yang HH; Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., Hu Y; Center for Biomedical Informatics and Information Technology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., Wei J; Department of Surgery, Duke University, Durham, North Carolina, USA., Lei G; Department of Surgery, Duke University, Durham, North Carolina, USA., Yang XY; Department of Surgery, Duke University, Durham, North Carolina, USA., Madan R; Division of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA., Molinolo AA; Department of Pathology, University of California San Diego Moores Cancer Center, La Jolla, California, USA., Markiewicz MA; Department of Microbiology, Molecular Genetics, and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA., Chalise P; Department of Biostatistics and Data Science, University of Kansas Medical Center, Kansas City, Kansas, USA., Axelrod ML; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Balko JM; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Pathology Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Hunter KW; Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., Hartman ZC; Department of Surgery, Duke University, Durham, North Carolina, USA., Lange CA; Department of Medicine (Hematology, Oncology, and Transplantation), University of Minnesota Cancer Center, Minneapolis, Minnesota, USA.; Department of Pharmacology, University of Minnesota Cancer Center, Minneapolis, Minnesota, USA., Hagan CR; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA chagan@kumc.edu.; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, USA.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2021 May; Vol. 9 (5).

Structures of a DNA Polymerase Inserting Therapeutic Nucleotide Analogues.

Autor: Schaich MA; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center , Kansas City, Kansas 66160, United States., Smith MR; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center , Kansas City, Kansas 66160, United States., Cloud AS; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center , Kansas City, Kansas 66160, United States., Holloran SM; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center , Kansas City, Kansas 66160, United States., Freudenthal BD; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center , Kansas City, Kansas 66160, United States.

Publikováno v: Chemical research in toxicology [Chem Res Toxicol] 2017 Nov 20; Vol. 30 (11), pp. 1993-2001. Date of Electronic Publication: 2017 Sep 01.