Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Hollis R. O'Neal"'
Autor:
Hollis R. O’Neal, Jr, MD, MSc, Roya Sheybani, PhD, David R. Janz, MD, MSc, Robert Scoggins, MD, PhD, Tonya Jagneaux, MD, James E. Walker, MD, PhD, Daniel J. Henning, MD, MPH, Elizabeth Rosenman, MD, Simon A. Mahler, MD, MS, Hariharan Regunath, MD, Christopher S. Sampson, MD, D. Clark Files, MD, Richard D. Fremont, MD, Michael J. Noto, MD, PhD, Erica E. Schneider, MD, Wesley R. Shealey, MD, Matthew S. Berlinger, MD, Thomas C. Carver, MD, Morgan K. Walker, MD, Nathan A. Ledeboer, PhD, Ajay M. Shah, PhD, Henry T.K. Tse, PhD, Dino DiCarlo, PhD, Todd W. Rice, MD, MSc, Christopher B. Thomas, MD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 2, p e1026 (2024)
OBJECTIVES:. To assess the in vitro IntelliSep test, a microfluidic assay that quantifies the state of immune activation by evaluating the biophysical properties of leukocytes, as a rapid diagnostic for sepsis. DESIGN:. Prospective cohort study. SETT
Externí odkaz:
https://doaj.org/article/63538c9b3c63401cb6b64ae711591b01
Autor:
Christopher S. Hollenbeak, PhD, Daniel J. Henning, MD, MPH, Glenn K. Geeting, MD, Nathan A. Ledeboer, PhD, Imran A. Faruqi, MD, Christi G. Pierce, DSc, MSHA, MBA, Christopher B. Thomas, MD, Hollis R. O’Neal, Jr, MD, MS
Publikováno v:
Critical Care Explorations, Vol 5, Iss 7, p e0942 (2023)
OBJECTIVES:. Sepsis causes 270,000 deaths and costs $38 billion annually in the United States. Most cases of sepsis present in the emergency department (ED), where rapid diagnosis remains challenging. The IntelliSep Index (ISI) is a novel diagnostic
Externí odkaz:
https://doaj.org/article/5240e930099f498eb5899bad7b385d61
Autor:
Chadd K. Kraus, H. Bryant Nguyen, Ryan C. Jacobsen, Nathan A. Ledeboer, Larissa S. May, Hollis R. O'Neal Jr., Michael A. Puskarich, Todd W. Rice, Wesley H. Self, Richard E. Rothman
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract Objectives Recent research has helped define the complex pathways in sepsis, affording new opportunities for advancing diagnostics tests. Given significant advances in the field, a group of academic investigators from emergency medicine, int
Externí odkaz:
https://doaj.org/article/11d3d6d9ad1a49bea61795950db0b4ce
Autor:
Chadd K. Kraus, Hollis R. O’Neal, Nathan A. Ledeboer, Todd W. Rice, Wesley H. Self, Richard E. Rothman
Publikováno v:
Journal of Personalized Medicine, Vol 13, Iss 12, p 1685 (2023)
Potentially septic patients have a huge clinical and economic impact on hospitals and often present to the emergency department (ED) with undifferentiated symptoms. The triage of these patients is complex and has historically relied heavily upon prov
Externí odkaz:
https://doaj.org/article/88513e497f5f449f91b7a5481d5173ed
Autor:
Wesley H. Self, Thomas G. Stewart, Allison P. Wheeler, Wissam El Atrouni, Amanda J. Bistran-Hall, Jonathan D. Casey, Vince D. Cataldo, James D. Chappell, Claudia S. Cohn, Jessica B. Collins, Mark R. Denison, Marjolein de Wit, Sheri L. Dixon, Abhijit Duggal, Terri L. Edwards, Magali J. Fontaine, Adit A. Ginde, Michelle S. Harkins, Thelma Harrington, Estelle S. Harris, Daanish Hoda, Tina S. Ipe, Stuti J. Jaiswal, Nicholas J. Johnson, Alan E. Jones, Maryrose Laguio-Vila, Christopher J. Lindsell, Jason Mallada, Manoj J. Mammen, Ryan A. Metcalf, Elizabeth A. Middleton, Simon Mucha, Hollis R. O’Neal, Sonal R. Pannu, Jill M. Pulley, Xian Qiao, Jay S. Raval, Jillian P. Rhoads, Harry Schrager, Carl Shanholtz, Nathan I. Shapiro, Stephen J. Schrantz, Isaac Thomsen, Krista K. Vermillion, Gordon R. Bernard, Todd W. Rice, For the Passive Immunity Trial for Our Nation (PassITON) Investigators
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Convalescent plasma is being used widely as a treatment for coronavirus disease 2019 (COVID-19). However, the clinical efficacy of COVID-19 convalescent plasma is unclear. Methods The Passive Immunity Trial for Our Nation (PassITO
Externí odkaz:
https://doaj.org/article/09f00f69e5d142a1b19dcc01b4acebd6
Autor:
Matt G. Sorrells, Yurim Seo, Melia Magnen, Bliss Broussard, Roya Sheybani, Ajay M. Shah, Hollis R. O’Neal, Henry T. K. Tse, Mark R. Looney, Dino Di Carlo
Publikováno v:
Diagnostics, Vol 13, Iss 8, p 1435 (2023)
Sepsis, the leading cause of mortality in hospitals, currently lacks effective early diagnostics. A new cellular host response test, the IntelliSep test, may provide an indicator of the immune dysregulation characterizing sepsis. The objective of thi
Externí odkaz:
https://doaj.org/article/5a52e97f25ae417687b3341df0d63b3a
Autor:
Hollis R. O’Neal, Roya Sheybani, Terrell S. Caffery, Diana Hamer, L. Mark Laperouse, Mandi W. Musso, Catherine S. O’Neal, Henry T. K. Tse, Ajay M. Shah, Christopher B. Thomas
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Objective Assess the IntelliSep Index (ISI) for risk stratification of patients presenting to the Emergency Department (ED) with respiratory symptoms suspected of COVID-19 during the pandemic. Methods An observational single-center study of prospecti
Externí odkaz:
https://doaj.org/article/168ea2fc08ae457db9bf4950158955a5
Autor:
Hollis R. O’Neal, Jr, , MD, MSc, Roya Sheybani, PhD, Terrell S. Caffery, MD, Mandi W. Musso, PhD, Diana Hamer, PhD, Shannon M. Alwood, MD, Matthew S. Berlinger, MD, Tonya Jagneaux, MD, Katherine W. LaVie, MD, Catherine S. O’Neal, MD, Michael A. Sanchez, MD, Morgan K. Walker, MD, Ajay M. Shah, PhD, Henry T. K. Tse, PhD, Christopher B. Thomas, MD
Publikováno v:
Critical Care Explorations, Vol 3, Iss 6, p e0460 (2021)
Objectives:. Sepsis is a common cause of morbidity and mortality. A reliable, rapid, and early indicator can help improve efficiency of care and outcomes. To assess the IntelliSep test, a novel in vitro diagnostic that quantifies the state of immune
Externí odkaz:
https://doaj.org/article/bb5ce84bad614f819e71b65faafe4be1
Autor:
Wesley H. Self, Allison P. Wheeler, Thomas G. Stewart, Harry Schrager, Jason Mallada, Christopher B. Thomas, Vince D. Cataldo, Hollis R. O’Neal, Nathan I. Shapiro, Conor Higgins, Adit A. Ginde, Lakshmi Chauhan, Nicholas J. Johnson, Daniel J. Henning, Stuti J. Jaiswal, Manoj J. Mammen, Estelle S. Harris, Sonal R. Pannu, Maryrose Laguio-Vila, Wissam El Atrouni, Marjolein de Wit, Daanish Hoda, Claudia S. Cohn, Carla McWilliams, Carl Shanholtz, Alan E. Jones, Jay S. Raval, Simon Mucha, Tina S. Ipe, Xian Qiao, Stephen J. Schrantz, Aarthi Shenoy, Richard D. Fremont, Eric J. Brady, Robert H. Carnahan, James D. Chappell, James E. Crowe, Mark R. Denison, Pavlo Gilchuk, Laura J. Stevens, Rachel E. Sutton, Isaac Thomsen, Sandra M. Yoder, Amanda J. Bistran-Hall, Jonathan D. Casey, Christopher J. Lindsell, Li Wang, Jill M. Pulley, Jillian P. Rhoads, Gordon R. Bernard, Todd W. Rice
Publikováno v:
Chest. 162:982-994
Autor:
Hollis R O’Neal, Roya Sheybani, Miranda Mitchell, Henry T Tse, Ajay M Shah, Christopher B Thomas
Publikováno v:
Open Forum Infectious Diseases. 9
Background Sepsis is a common and costly condition encountered in United States hospitals and Emergency Departments (ED). Studies have shown that the incidence of sepsis and risk of sepsis morbidity and mortality increases with age. With increased ef