Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hollis D, Showalter"'
Autor:
Walajapet Rajeswaran, Shireen R. Ashkar, Pil H. Lee, Larisa Yeomans, Yeonoh Shin, Scott G. Franzblau, Katsuhiko S. Murakami, Hollis D. Showalter, George A. Garcia
Publikováno v:
ACS Infectious Diseases. 8:1422-1438
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9719d710e2c40aa8a193664469e30de
https://doi.org/10.1021/acsinfecdis.1c00636
https://doi.org/10.1021/acsinfecdis.1c00636
Autor:
Hollis D. Showalter
Publikováno v:
Molecules, Vol 25, Iss 18, p 4137 (2020)
Nitroimidazole drugs have a long history as therapeutic agents to treat bacterial and parasitic diseases. The discovery in 1989 of a bicyclic nitroimidazole lead, displaying in vitro and in vivo antitubercular activity, spurred intensive exploration
Externí odkaz:
https://doaj.org/article/32d9c96ba26c42f3a72c264ff38df19a
Autor:
Marie-Eve Charbonneau, Marta J Gonzalez-Hernandez, Hollis D Showalter, Nicholas J Donato, Christiane E Wobus, Mary X D O'Riordan
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104096 (2014)
The global spread of anti-microbial resistance requires urgent attention, and diverse alternative strategies have been suggested to address this public health concern. Host-directed immunomodulatory therapies represent one approach that could reduce
Externí odkaz:
https://doaj.org/article/8ab2ef79d5e34366a8e062b0ae6f83a4
Autor:
Marta J Gonzalez-Hernandez, Anupama Pal, Kofi E Gyan, Marie-Eve Charbonneau, Hollis D Showalter, Nicholas J Donato, Mary O'Riordan, Christiane E Wobus
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94491 (2014)
Most antiviral treatment options target the invading pathogen and unavoidably encounter loss of efficacy as the pathogen mutates to overcome replication restrictions. A good strategy for circumventing drug resistance, or for pathogens without treatme
Externí odkaz:
https://doaj.org/article/e29f5e9155354f19a94c1fe5eb87bd0c
Autor:
Jeffrey W Perry, Mohammad Ahmed, Kyeong-Ok Chang, Nicholas J Donato, Hollis D Showalter, Christiane E Wobus
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002783 (2012)
Ubiquitin (Ub) is a vital regulatory component in various cellular processes, including cellular responses to viral infection. As obligate intracellular pathogens, viruses have the capacity to manipulate the ubiquitin (Ub) cycle to their advantage by
Externí odkaz:
https://doaj.org/article/0eae994720e640198ac9b78436c0ae51
Autor:
Alex J, McDonald, Deborah R, Leon, Kathleen A, Markham, Bei, Wu, Christian F, Heckendorf, Kevin, Schilling, Hollis D, Showalter, Philip C, Andrews, Mark E, McComb, M Jake, Pushie, Catherine E, Costello, Glenn L, Millhauser, David A, Harris
Publikováno v:
Structure
The cellular isoform of the prion protein (PrP(C)) serves as precursor to the infectious isoform (PrP(Sc)), and as a cell-surface receptor, which binds misfolded protein oligomers as well as physiological ligands such as Cu(2+) ions. PrP(C) consists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec182716fe673fbd7ef9920baf6e3e6a
https://pubmed.ncbi.nlm.nih.gov/30956132
https://pubmed.ncbi.nlm.nih.gov/30956132