PspA Family Typing and PCR-Based DNA Fingerprinting with BOX A1R Primer of Pneumococci from the Blood of Patients in the USA with and without Sickle Cell Disease

Autor: Payne, D. B., Sun, A., Butler, J. C., Singh, S. P., Hollingshead, S. K., Briles, D. E.

Publikováno v: Epidemiology and Infection, 2005 Feb 01. 133(1), 173-178.

Externí odkaz: https://www.jstor.org/stable/3865560

Conserved residues in Ycf54 are required for protochlorophyllide formation in Synechocystis sp. PCC 6803

Autor: Hollingshead, S., Bliss, S., Baker, P.J., Hunter, C.N.

Publikováno v: Biochemical Journal

Chlorophylls (Chls) are modified tetrapyrrole molecules, essential for photosynthesis. These pigments possess an isocyclic E ring formed by the Mg-protoporphyrin IX monomethylester cyclase (MgPME-cyclase). We assessed the in vivo effects of altering

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eecfdbbe7c5906edc065a4a443ca338b
https://doi.org/10.1042/bcj20161002

Maintenance of the virulence plasmid in Shigella flexneri is influenced by Lon and two functional partitioning systems

Autor: McVicker, G, Hollingshead, S, Pilla, G, Tang, CM

Publikováno v: Molecular Microbiology

Members of the genus Shigella carry a large plasmid, pINV, which is essential for virulence. In Shigella flexneri, pINV harbours three toxin -antitoxin (TA) systems, CcdAB, GmvAT and VapBC that promote vertical transmission of the plasmid. Type II TA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ff30a0e2fd7d65238ad7bfb0a852ec9d
https://doi.org/10.1111/mmi.14225

Structure-based design of chimeric antigens for multivalent protein vaccines

Autor: Hollingshead, S, Jongerius, I, Exley, R, Johnson, S, Lea, S, Tang, C

Publikováno v: Nature Communications, 9(1). Nature Publishing Group
'Nature Communications ', vol: 9, pages: 1051-1-1051-10 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)

There is an urgent need to develop vaccines against pathogenic bacteria. However, this is often hindered by antigenic diversity and difficulties encountered manufacturing membrane proteins. Here we show how to use structure-based design to develop ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a70c40c65c4b4ce91a2f9a503f5ce3bf
https://dspace.library.uu.nl/handle/1874/366909

emm typing and validation of provisional M types for group A streptococci

Autor: Facklam, R. R., Beall, B., Efstratiou, A., Fischetti, V., Johnson, D., Kaplan, E., Kriz, P., Lovgren, M., Martin, D., Schwartz, B., Artem Totolian, Bessen, D., Hollingshead, S., Rubin, F., Scott, J., Tyrrell, G.

Publikováno v: Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 5, Iss 2, Pp 247-253 (1999)
Scopus-Elsevier

This report discusses the following issues related to typing of group A streptococci (GAS): The development and use of the 5' emm variable region sequencing (emm typing) in relation to the existing serologic typing system; the designation of emm type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3fa6bef09ff278898df72bab214d0907
http://europepmc.org/articles/PMC2640698