Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Holli B Hutcheson"'
Autor:
Pardis C Sabeti, Emily Walsh, Steve F Schaffner, Patrick Varilly, Ben Fry, Holli B Hutcheson, Mike Cullen, Tarjei S Mikkelsen, Jessica Roy, Nick Patterson, Richard Cooper, David Reich, David Altshuler, Stephen O'Brien, Eric S Lander
Publikováno v:
PLoS Biology, Vol 3, Iss 11, p e378 (2005)
The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Delta32) allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that CCR5-Delta32 arose within the past 1,000 y and rose to its present high frequ
Externí odkaz:
https://doaj.org/article/08cd36e6040b4450862144729a1f1a28
Autor:
Susan E. Folstein, Yuki Bradford, Kai Wang, Terry A. Braun, Joseph Piven, Val C. Sheffield, Susan L. Santangelo, Wen Huang, Tom Cassavant, Jonathan L. Haines, Marybeth Gardiner, Holli B. Hutcheson, Veronica J. Vieland
Publikováno v:
American Journal of Medical Genetics. 105:539-547
We investigated the effect of incorporating information about proband and parental structural language phenotypes into linkage analyses in the two regions for which we found the highest signals in our first-stage affected sibling pair genome screen:
Autor:
Jason C. Poole, Efe Sezgin, Sharyne Donfield, Lawrence A. Kingsley, Sher L. Hendrickson, Douglas C. Wallace, James J. Goedert, David Vlahov, Eduardo Ruiz-Pesini, Holli B. Hutcheson, Stephen J. O'Brien, James A. Lautenberger
Objective: Mitochondrial function plays a role in both AIDS progression and HAART toxicity; therefore, we sought to determine whether mitochondrial DNA variation revealed novel AIDS restriction genes, particularly as mitochondrial DNA singlenucleotid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26125e8b864fbae8d55a42838c74bb7d
https://europepmc.org/articles/PMC2699618/
https://europepmc.org/articles/PMC2699618/
Autor:
George W. Nelson, Michael W. Smith, Randall C. Johnson, Joan Pontius, Holli B. Hutcheson, Stephen J. O'Brien, Bailey Kessing, James A. Lautenberger, Cheryl A. Winkler, Sharyne Donfield, Robert M. Stephens, James J. Goedert, John P. Phair
Publikováno v:
Vaccine. 26(24)
The screening of common genetic polymorphisms among candidate genes for AIDS pathology in HIV exposed cohort populations has led to the description of 20 AIDS restriction genes (ARGs), variants that affect susceptibility to HIV infection or to AIDS p
Autor:
Ying Qi, Lisa P. Jacobson, Mary Carrington, Frank Maldarelli, Galit Alter, Traci E. Yamashita, Randall C. Johnson, Gabriela Bleiber, Susan Buchbinder, David Vlahov, Arman Bashirova, Amalio Telenti, Holli B. Hutcheson, Stephen J. O'Brien, Jie Cheng, James J. Goedert, Margaret T May, Keith Hoots
Publikováno v:
Journal of virology. 80(14)
Tumor susceptibility gene 101 ( TSG101 ) encodes a host cellular protein that is appropriated by human immunodeficiency virus type 1 (HIV-1) in the budding process of viral particles from infected cells. Variation in the coding or noncoding regions o
Autor:
Jessica Roy, Mike Cullen, Richard Cooper, David Reich, Holli B. Hutcheson, Stephen J. O'Brien, Patrick Varilly, Tarjei S. Mikkelsen, Nick Patterson, Emily C. Walsh, Eric S. Lander, Pardis C. Sabeti, David Altshuler, Stephen F. Schaffner, Ben Fry
Publikováno v:
PLoS Biology
PLoS Biology, Vol 3, Iss 11, p e378 (2005)
PLoS Biology, Vol 3, Iss 11, p e378 (2005)
The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Δ32) allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that CCR5-Δ32 arose within the past 1,000 y and rose to its present high frequency (
Autor:
Stephen F. Schaffner, Yi Zeng, Pardis C. Sabeti, Cheryl A. Winkler, Paul I.W. de Bakker, Emily C. Walsh, Alejandro A. Palma, Richard S. Cooper, Ben Fry, Eric S. Lander, Holli B. Hutcheson, Stephen J. O'Brien, Patrick Varilly, David Altshuler, Jessica Roy
Publikováno v:
Human genetics. 119(1-2)
Pathogens have played a substantial role in human evolution, with past infections shaping genetic variation at loci influencing immune function. We selected 168 genes known to be involved in the immune response, genotyped common single nucleotide pol
Autor:
Susan Buchbinder, Holli B. Hutcheson, Stephen J. O'Brien, James J. Goedert, Maureen P. Martin, Roger Detels, George W. Nelson, Yvette van Kooyk, David Vlahov, Michael M. Lederman, Mary Carrington, Keith Hoots
Publikováno v:
Martin, M P, Lederman, M M, Hutcheson, H B, Goedert, J J, Nelson, G W, van Kooyk, Y, Detels, R, Buchbinder, S, Hoots, K, Vlahov, D, O'Brien, S J & Carrington, M 2004, ' Association of DC-SIGN promoter polymorphism with increased risk for parenteral, but not mucosal, acquisition of human immunodeficiency virus type 1 infection ', Journal of Virology, vol. 78, no. 24, pp. 14053-6 . https://doi.org/10.1128/JVI.78.24.14053-14056.2004
Journal of Virology, 78(24), 14053-6. American Society for Microbiology
Journal of Virology, 78(24), 14053-6. American Society for Microbiology
There is considerable debate about the fundamental mechanisms that underlie and restrict acquisition of human immunodeficiency virus type 1 (HIV-1) infection. In light of recent studies demonstrating the ability of C type lectins to facilitate infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395f7c59f9faa0982e0936d9125ab7d0
https://research.vumc.nl/ws/files/10728678/PMC533922
https://research.vumc.nl/ws/files/10728678/PMC533922
Autor:
Susan E. Folstein, James S. Sutcliffe, Jonathan L. Haines, Holli B. Hutcheson, Susan L. Santangelo, M. B. Gardiner, Yuki Bradford
Publikováno v:
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. (1)
Previous genetic and cytogenetic studies provide evidence that points to one or more autism susceptibility genes residing on chromosome 7q (AUTS1, 115–149 cM on the Marshfield map). However, further localization using linkage analysis has proven di
Autor:
Anton Svitin, Nikolay Cherkazov, Sergey V. Malov, Pavel Dobrynin, Holli B. Hutcheson, Stephen J. O'Brien, Efe Sezgin, Paul Geerts, Sher Hendrickson-Lambert, Jennifer L. Troyer
Publikováno v:
Journal of Acquired Immune Deficiency Syndromes (1999)
As genome wide association studies plus whole genome sequence analyses for complex human disease determinants are expanding, it seems useful to develop strategies to facilitate large data sharing, rapid replication and validation of provocative stati