Human immunodeficiency virus type I-specific CD8+ T cell subset abnormalities in chronic infection persist through effective antiretroviral therapy

Autor: Gallant Maureen E, Hollett Natasha A, Zipperlen Katrin, Pohling Julia, Grant Michael D

Publikováno v: BMC Infectious Diseases, Vol 10, Iss 1, p 129 (2010)

Abstract Background Effective highly active antiretroviral therapy (HAART) reduces human immunodeficiency virus (HIV) replication, restores CD4+ T lymphocyte counts and greatly reduces the incidence of opportunistic infections. While this demonstrate

Externí odkaz: https://doaj.org/article/a2ad6a45a7bf44529fddc76e4509bcfc

DOCK2 Deficiency Causes Defects in Antiviral T-Cell Responses and Impaired Control of Herpes Simplex Virus Infection.

Autor: Randall KL; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.; School of Medicine and Psychology, The Australian National University, Canberra, ACT, Australia., Flesch IEA; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Mei Y; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Miosge LA; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Aye R; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Yu Z; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Domaschenz H; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Hollett NA; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Russell TA; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Stefanovic T; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Wong YC; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Seneviratne S; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Ballard F; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Hernandez Gallardo R; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Croft SN; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Goodnow CC; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.; Garvan Institute of Medical Research, University of New South Wales, Darlinghurst, NSW, Australia., Bertram EM; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Enders A; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Tscharke DC; Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2024 Sep 23; Vol. 230 (3), pp. e712-e721.

Extent of Systemic Spread Determines CD8+ T Cell Immunodominance for Laboratory Strains, Smallpox Vaccines, and Zoonotic Isolates of Vaccinia Virus.

Autor: Flesch IE; Research School of Biology, Australian National University, Canberra, Australian Capital Territory 2601, Australia;, Hollett NA; Research School of Biology, Australian National University, Canberra, Australian Capital Territory 2601, Australia;, Wong YC; Research School of Biology, Australian National University, Canberra, Australian Capital Territory 2601, Australia;, Quinan BR; Research School of Biology, Australian National University, Canberra, Australian Capital Territory 2601, Australia; Laboratório de Virologia Básica e Aplicada, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil; and., Howard D; John Curtin School of Medical Research, Australian National University, Canberra, Australian Capital Territory 2601, Australia., da Fonseca FG; Laboratório de Virologia Básica e Aplicada, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil; and., Tscharke DC; Research School of Biology, Australian National University, Canberra, Australian Capital Territory 2601, Australia; John Curtin School of Medical Research, Australian National University, Canberra, Australian Capital Territory 2601, Australia david.tscharke@anu.edu.au.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2015 Sep 01; Vol. 195 (5), pp. 2263-72. Date of Electronic Publication: 2015 Jul 20.

Distinct APC subtypes drive spatially segregated CD4+ and CD8+ T-cell effector activity during skin infection with HSV-1.

Autor: Macleod BL; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Bedoui S; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Hor JL; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Mueller SN; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Russell TA; Division of Biomedical Science and Biochemistry, Research School of Biology, The Australian National University, Canberra, Australian Capital Territory, Australia., Hollett NA; Division of Biomedical Science and Biochemistry, Research School of Biology, The Australian National University, Canberra, Australian Capital Territory, Australia., Heath WR; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Tscharke DC; Division of Biomedical Science and Biochemistry, Research School of Biology, The Australian National University, Canberra, Australian Capital Territory, Australia., Brooks AG; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Gebhardt T; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.

Publikováno v: PLoS pathogens [PLoS Pathog] 2014 Aug 14; Vol. 10 (8), pp. e1004303. Date of Electronic Publication: 2014 Aug 14 (Print Publication: 2014).

Heteroclitic peptides enhance human immunodeficiency virus-specific CD8(+) T cell responses.

Autor: Gladney KH; Division of BioMedical Sciences, Memorial University of Newfoundland and Labrador, St. John's, NL, Canada A1B 3V6. kristagladney@hotmail.com, Pohling J, Hollett NA, Zipperlen K, Gallant ME, Grant MD

Publikováno v: Vaccine [Vaccine] 2012 Nov 19; Vol. 30 (49), pp. 6997-7004. Date of Electronic Publication: 2012 Oct 08.