Výsledky vyhledávání - "Holger W. Hirte"

Table S 1-6 and Figures S1-3 from Dose-Ranging and Cohort-Expansion Study of Monalizumab (IPH2201) in Patients with Advanced Gynecologic Malignancies: A Trial of the Canadian Cancer Trials Group (CCTG): IND221

Autor: Lesley Seymour, Janelle Ramsahai, Shirley-Ann Hahn, Nathalie Grenier, Paulo Paralejas, Hatem A. Azim, Dongsheng Tu, Heather Ritter, Marcus Butler, Diane Provencher, Holger W. Hirte, Anna V. Tinker

Correlative studies and additional data as requested by reviewers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2841e00a89924669035b5d46038b19
https://doi.org/10.1158/1078-0432.22471739.v1

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Supplementary Data from Phase I Study of Decitabine in Combination with Vorinostat in Patients with Advanced Solid Tumors and Non-Hodgkin's Lymphomas

Autor: Lillian L. Siu, Merrill J. Egorin, Julianne L. Holleran, Igor Espinoza-Delgado, Wen-jiang Zhang, Lisa Wang, Shauna McGill, Lee-Anne Stayner, Anne Laughlin, Sheila Webster, Patricia Moretto, Amit M. Oza, Holger W. Hirte, Eric X. Chen, Sebastien J. Hotte, Anastasios Stathis

Supplementary Figure S1.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0422847df9e3a8453edb9d56aa4e04
https://doi.org/10.1158/1078-0432.22442208.v1

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Data from Dose-Ranging and Cohort-Expansion Study of Monalizumab (IPH2201) in Patients with Advanced Gynecologic Malignancies: A Trial of the Canadian Cancer Trials Group (CCTG): IND221

Purpose:Monalizumab binds CD94/NKG2A, preventing HLA-E inhibition of tumor lymphocytes. A dose-ranging/cohort expansion trial of monalizumab for recurrent gynecologic malignancies was conducted to determine the recommended phase II dose (RP2D) and to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9704cd103acaba8a315475b81f2aa31e
https://doi.org/10.1158/1078-0432.c.6527987.v1

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Data from Phase I Study of Decitabine in Combination with Vorinostat in Patients with Advanced Solid Tumors and Non-Hodgkin's Lymphomas

Purpose: This phase I study evaluated the safety, tolerability, pharmacokinetics, and preliminary efficacy of the combination of decitabine with vorinostat.Patients and Methods: Patients with advanced solid tumors or non-Hodgkin's lymphomas were elig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00707092063e5fcdd3f45bde6e041bf6
https://doi.org/10.1158/1078-0432.c.6519009

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A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients

Autor: Manijeh, Daneshmand, Doris A E, Parolin, Holger W, Hirte, Pierre, Major, Glenwood, Goss, David, Stewart, Gerald, Batist, Wilson H, Miller, Sarah, Matthews, Lesley, Seymour, Ian A J, Lorimer

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 9(7)

Epidermal growth factor receptor (EGFR) appears to play an important role in the pathogenesis of colorectal cancer. We have performed a Phase I/II study of the EGFR tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients in which se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::13291aa7f07ee5a6b39060bc20c4f669
https://pubmed.ncbi.nlm.nih.gov/12855618

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Doxycycline decreases tumor burden in a bone metastasis model of human breast cancer

Autor: Wilhelmina C M, Duivenvoorden, Snezana Vukmirović, Popović, Sárka, Lhoták, Eric, Seidlitz, Holger W, Hirte, Richard G, Tozer, Gurmit, Singh

Publikováno v: Cancer research. 62(6)

Bone is one of the most frequent sites for metastasis in breast cancer patients,often resulting in significant clinical morbidity and mortality. Increased matrix metalloproteinase (MMP) activity of tumor cells correlates with a higher invasive and me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e4f89a2b41d50e67a6b723fbdfe8fda8
https://pubmed.ncbi.nlm.nih.gov/11912125

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Akademický článek

Intraperitoneal chemotherapy in the first‐line treatment of women with stage III epithelial ovarian cancerSee related article on pages 645–9, this issue.: A Systematic Review With Metaanalyses.

Autor: Laurie Elit, Thomas K. Oliver, Allan Covens, Janice Kwon, Michael Fung‐Kee Fung, Holger W. Hirte, Amit M. Oza

Publikováno v: Cancer (0008543X); Feb2007, Vol. 109 Issue 4, p692-702, 11p

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Akademický článek

A phase II trial of ZD1839 (Iressa™) 750 mg per day, an oral epidermal growth factor receptor-tyrosine kinase inhibitor, in patients with metastatic colorectal cancer.

Autor: Mary J. MacKenzie, Holger W. Hirte, Goss Glenwood, Maroun Jean, Rakesh Goel, Pierre P. Major, Wilson H. Miller Jr., Lawrence Panasci, Ian A. J. Lorimer, Gerald Batist, Sarah Matthews, Lynn Douglas, Lesley Seymour

Publikováno v: Investigational New Drugs; Jan2005, Vol. 23 Issue 2, p165-170, 6p

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