Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Holger Ulbrich"'
Publikováno v:
Clinical Oral Investigations. 19:139-148
Bisphosphonate-associated osteonecrosis of the jaws is a serious side effect that mainly occurs in patients receiving highly potent, nitrogen-containing bisphosphonates. Usually the diagnosis is made due to exposed bone and a nonhealing wound. Neutro
Autor:
Holger Ulbrich, Pawan K. Sharma, Som N. Dhawan, Surender Kumar, Sukhbir Lal, Karan Singh, Gerd Dannhardt, Pawan Kumar
Publikováno v:
Medicinal Chemistry Research. 20:239-244
Novel series of pyrazolo[3,4-b]pyridines with basic skeleton different from the known COX inhibitors were synthesized from 5-amino-1-[4-(aminosulfonyl)phenyl]-3-phenyl-1H-pyrazole, which in turn was prepared by the condensation of (4-sulfamoylphenyl)
Autor:
Holger Ulbrich, Andreas Mattern, Michael Scholz, Gerd Dannhardt, Oliver Soehnlein, Lennart Lindbom
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:558-568
Three series of non-steroidal anti-inflammatory drugs (NSAIDs) inhibiting the cyclooxygenase/5-lipoxygenase (COX/5-LOX) pathways as such as formation of hydroxyl radicals and adhesion were prepared: 4,5-diaryl isothiazoles, 4,5-diaryl 3H-1,2-dithiole
Publikováno v:
European Journal of Medicinal Chemistry. 43:1152-1159
The aim of this study was to investigate 4,5-diaryl isoselenazoles as multiple target non-steroidal anti-inflammatory drugs (MTNSAIDs) which can intervene into the inflammatory processes via different mechanisms of action creating a new class of comp
Autor:
Werner Kiefer, Holger Ulbrich, Jan-Peter Kramb, Gerd Dannhardt, Andreas Mattern, Michael Scholz
Publikováno v:
Archiv der Pharmazie. 341:281-287
The aim was to study the COX-1 inhibiting efficacy in context with hydroxyl radical scavenging properties of compounds bearing a carboxylic acid and ester function, respectively. In general, the acids are more potent radical scavengers than the corre
Publikováno v:
Biomarker Insights, Vol 3, Pp 387-402 (2008)
Biomarker Insights
Biomarker Insights, Vol 3 (2008)
Biomarker Insights
Biomarker Insights, Vol 3 (2008)
Glaucoma is characterized by a loss of retinal ganglion cells (RGC) which is associated with a decrease of visual function. Neuroprotective agents as a new therapeutic strategy could prevent the remaining neurons from apoptotic cell death. Previous s
Publikováno v:
European Journal of Medicinal Chemistry. 37:953-959
A series of 6,7-diaryl-2,3-1H-dihydropyrrolizines was prepared as COX-1/COX-2 and 5-LOX inhibitors. The inhibition of COX-1 was evaluated using intact bovine platelets as the enzyme source, whereas LPS-stimulated human monocytes served as the enzyme
Autor:
Holger Ulbrich, Gerd Dannhardt
Publikováno v:
Pharmazie in unserer Zeit. 31:146-154
NSAR sind etablierte Arzneistoffe zur Behandlung entzundlicher Erkrankungen wie z.B. der rheumatoiden Arthritis, der Osteoarthritis und der Arthrose. In den letzten Jahren ist durch die Entwicklung von selektiven COX-2-Hemmstoffen der Arzneischatz be
Autor:
G. Paul Savage, Anna Bezos, Satish Chand, Holger Ulbrich, Christopher R. Parish, Gerd Dannhardt, Werner Kiefer, Martin G. Banwell, Ulrike Nowe
Publikováno v:
Org. Biomol. Chem.. 1:2427-2429
Treatment of an equimolar mixture of stilbene 7 and cinnamyl alcohol 8 with silver carbonate in acetone–benzene afforded a ca. 2 : 1 : 2 : 1 mixture of the stilbenolignan (±)-aiphanol (1) and congeners 2–4 each of which show significant anti-ang
Autor:
Holger Ulbrich, Markus Braden
Several non-cuprates layered transition-metal oxides exhibit clear evidence for stripe ordering of charges and magnetic moments. Therefore, stripe order should be considered as the typical consequence of doping a Mott insulator, but only in cuprates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d90a7b39e86c3799fdb3f3294c45a3
http://arxiv.org/abs/1201.2356
http://arxiv.org/abs/1201.2356