Zobrazeno 1 - 10
of 908
pro vyhledávání: '"Holger Stark"'
Autor:
Annika Balzulat, W. Felix Zhu, Cathrin Flauaus, Victor Hernandez‐Olmos, Jan Heering, Sunesh Sethumadhavan, Mariam Dubiel, Annika Frank, Amelie Menge, Maureen Hebchen, Katharina Metzner, Ruirui Lu, Robert Lukowski, Peter Ruth, Stefan Knapp, Susanne Müller, Dieter Steinhilber, Inga Hänelt, Holger Stark, Ewgenij Proschak, Achim Schmidtko
Publikováno v:
Advanced Science, Vol 11, Iss 15, Pp n/a-n/a (2024)
Abstract Various disorders are accompanied by histamine‐independent itching, which is often resistant to the currently available therapies. Here, it is reported that the pharmacological activation of Slack (Kcnt1, KNa1.1), a potassium channel highl
Externí odkaz:
https://doaj.org/article/1458b733707e4809ab4a13b283445821
Autor:
Benjamin Owen, Konstantinos Kechagidis, Sajad Razavi Bazaz, Romain Enjalbert, Erich Essmann, Calum Mallorie, Fatemehsadat Mirghaderi, Christian Schaaf, Krishnaveni Thota, Rohan Vernekar, Qi Zhou, Majid Ebrahimi Warkiani, Holger Stark, Timm Krüger
Publikováno v:
Advances in Physics: X, Vol 8, Iss 1 (2023)
ABSTRACTInertial particle microfluidics (IPMF) is an emerging technology for the manipulation and separation of microparticles and biological cells. Since the flow physics of IPMF is complex and experimental studies are often time-consuming or costly
Externí odkaz:
https://doaj.org/article/b3c220be10e04dd298dc649ae6ec243f
Autor:
Tereza Hofmanova, Carolina Marques, Alfonso T. García-Sosa, Óscar López, Luisa Leitzbach, Elisabete P. Carreiro, Aday González-Bakker, Adrián Puerta, Holger Stark, José M. Padrón, José G. Fernández-Bolaños, Anthony J. Burke
Publikováno v:
Results in Chemistry, Vol 6, Iss , Pp 101032- (2023)
The oxindole core is an important structural motif in many natural and synthetic substances with various biological activities including anticancer, antineurodegenerative, and antimicrobial properties. This report focuses on the synthesis and biologi
Externí odkaz:
https://doaj.org/article/75d359ef21d247a498f7e6bdb867b7b7
Autor:
Donia E. Hafez, Mariam Dubiel, Gabriella La Spada, Marco Catto, David Reiner-Link, Yu-Ting Syu, Mohammad Abdel-Halim, Tsong-Long Hwang, Holger Stark, Ashraf H. Abadi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
AbstractNeurodegenerative diseases such as Alzheimer’s disease (AD) are multifactorial with several different pathologic mechanisms. Therefore, it is assumed that multitargeted-directed ligands (MTDLs) which interact with different biological targe
Externí odkaz:
https://doaj.org/article/524cab4f650e41a28fe24ba5d6089fe3
Publikováno v:
Communications Physics, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Microswimmer suspensions in Newtonian fluids exhibit unusual macroscale properties, such as a superfluidic behavior, which can be harnessed to perform work at microscopic scales. Since most biological fluids are non-Newtonian, here we study
Externí odkaz:
https://doaj.org/article/b1b42e123e9c4ffea058a440edc2121b
Autor:
Javad Alizadeh, Simone C. da Silva Rosa, Xiaohui Weng, Joadi Jacobs, Shahrokh Lorzadeh, Amir Ravandi, Rui Vitorino, Stevan Pecic, Aleksandra Zivkovic, Holger Stark, Shahla Shojaei, Saeid Ghavami
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 3, Pp 151337- (2023)
Different studies corroborate a role for ceramide synthases and their downstream products, ceramides, in modulation of apoptosis and autophagy in the context of cancer. These mechanisms of regulation, however, appear to be context dependent in terms
Externí odkaz:
https://doaj.org/article/0a220444c1d8400c9a3998838f3a5068
Autor:
Till Welker, Holger Stark
Publikováno v:
New Journal of Physics, Vol 26, Iss 5, p 053039 (2024)
To explore the coupling between a growing population of microorganisms such as E. coli and a nonuniform nutrient distribution, we formulate a minimalistic model. It consists of active Brownian particles that divide and grow at a nutrient-dependent ra
Externí odkaz:
https://doaj.org/article/ef45ba7c257a4187a5967d07bcbf1399
Publikováno v:
Frontiers in Physics, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/b9eb5f6717924e909f30810c02a14920
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract We present a Brownian dynamics study of a 2D bath of active particles interacting among each other through usual steric interactions and, additionally, via non-reciprocal avoidant orientational interactions. We motivate them by the fact that
Externí odkaz:
https://doaj.org/article/e0f3335d330048cb9347662a66a2b44c
Publikováno v:
Communications Physics, Vol 5, Iss 1, Pp 1-9 (2022)
The investigation of microswimmer dynamics provides key insights in the design of active microfluidic systems and opens doors for further studies on inertial active matter. The authors establish a theoretical foundation for the dynamics of microswimm
Externí odkaz:
https://doaj.org/article/2ee16326282340559743265f6d157c4a