Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Holger Seltmann"'
Publikováno v:
Photodermatology, Photoimmunology & Photomedicine. 38:611-613
Autor:
Nikolaos G. Bonitsis, Holger Seltmann, Klaus Langner, Georgios Nikolakis, Ioannis Karagiannidis, Olivier Join-Lambert, Stefanos Bonovas, Thomas Wild, Silvia Zolke-Fischer, Aikaterini I. Liakou, Christos C. Zouboulis
Publikováno v:
Acta Dermato Venereologica. 97:493-498
It is unclear whether bacterial colonization in hidradenitis suppurativa/acne inversa (HS) comprises a primary cause, triggering factor or secondary phenomenon of the disease pathogenesis. Furthermore, the connection between certain bacterial species
Autor:
Christos C. Zouboulis, R. Kubba, Mohamed Badawy Abdel-Naser, Menon Gk, Amir M. Hossini, Holger Seltmann
Publikováno v:
Acta Dermato Venereologica. 97:313-320
Calcium and 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) are promoters of epithelial cell functions; however their effects on sebaceous glands are unknown. In this study, morphology, ultrastructure, cell numbers, lipid synthesis and apoptosis of SZ95 seboc
Autor:
Christos C. Zouboulis, Georgios Nikolakis, Jürgen Knolle, Evgenia Makrantonaki, Holger Seltmann, Amir M. Hossini
Publikováno v:
Experimental Dermatology. 24:497-502
The sebaceous gland displays key functions of the human skin, such as hormone synthesis in situ, antimicrobial activity and participation to inflammatory responses. Consequently, there is an emerging need of advanced in vitro models to study complex
Publikováno v:
British Journal of Dermatology. 165:269-276
Background Treatment of SZ95 sebocytes with the essential fatty acid linoleic acid (LA) and the polyunsaturated fatty acid arachidonic acid (AA) leads to sebaceous lipogenesis. Animal data indicate that stearoyl-coenzyme A desaturase (SCD), a key enz
Autor:
Holger Seltmann, C. C. Zouboulis, Alexei Gratchev, C. Fademrecht, Hjalmar Kurzen, Sergij Goerdt
Publikováno v:
Experimental Dermatology. 15:643-648
Extraneuronal acetylcholine (ACh) has been demonstrated to influence a plethora of cutaneous cell functions in an autocrine, paracrine and endocrine fashion. Previously, we could demonstrate a differentiation-specific expression of its nicotinic (nAC
Autor:
Thomas Mammone, Holger Seltmann, Daniel H. Maes, Edward Pelle, James Timothy Mccarthy, Xi Huang, Christos C. Zouboulis
Publikováno v:
Journal of Investigative Dermatology. 128(5):1280-1285
Overproduction of sebum, especially during adolescence, is causally related to acne and inflammation. As a way to reduce sebum and its interference with the process of follicular keratinization in the pilosebaceous unit leading to inflammatory acne l
Autor:
Monika Schäfer-Korting, Christos C. Zouboulis, Hans Christian Korting, Tobias Blaschke, Jana Štecová, W. Mehnert, Burkhard Kleuser, K.D. Kramer, Holger Seltmann, Ramadurai Sivaramakrishnan
Publikováno v:
Pharmaceutical Research. 24:991-1000
Topical cyproterone acetate (CPA) treatment of skin diseases should reduce side effects currently excluding the use in males and demanding contraceptive measures in females. To improve skin penetration of the poorly absorbed drug, we intended to iden
Publikováno v:
Experimental Dermatology. 15:769-774
Platelet-activating factor (PAF) is a group of phosphocholines with various biological effects mediated by the PAF receptor (PAF-R). Activation of the epidermal PAF-R induces the expression of inflammatory mediators, including cyclooxygenase-2 (COX-2
Publikováno v:
Journal of Investigative Dermatology. 126(1):42-48
Peroxisome proliferator-activated receptor gamma (PPARgamma) is thought to play a role in sebaceous gland cell function. We previously demonstrated in human epidermoid carcinoma KB cells that UVB irradiation activates PPARgamma via the generation of