Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Holger Schluter"'
Autor:
Agata Radwanska, Christopher Travis Cottage, Antonio Piras, Catherine Overed-Sayer, Carina Sihlbom, Ramachandramouli Budida, Catherine Wrench, Jane Connor, Susan Monkley, Petra Hazon, Holger Schluter, Matthew J. Thomas, Cory M. Hogaboam, Lynne A. Murray
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
Idiopathic pulmonary fibrosis (IPF) is a chronic disease of unmet medical need. It is characterized by formation of scar tissue leading to a progressive and irreversible decline in lung function. IPF is associated with repeated injury, which may alte
Externí odkaz:
https://doaj.org/article/893273a899624c7f8501668b4c65941b
Autor:
Jelena Weckerle, Sergio Picart-Armada, Stephan Klee, Tom Bretschneider, Andreas H. Luippold, Wolfgang Rist, Christian Haslinger, Holger Schlüter, Matthew J. Thomas, Bartlomiej Krawczyk, Francesc Fernandez-Albert, Marc Kästle, Daniel Veyel
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 1 (2022)
Alterations in metabolic pathways were recently recognized as potential underlying drivers of idiopathic pulmonary fibrosis (IPF), translating into novel therapeutic targets. However, knowledge of metabolic and lipid regulation in fibrotic lungs is l
Externí odkaz:
https://doaj.org/article/fe96aab995ee466cbc2caa0fdb471e3f
Autor:
Engin Baturcam, Stefan Vollmer, Holger Schlüter, Rose A. Maciewicz, Nisha Kurian, Outi Vaarala, Stephan Ludwig, Danen Mootoosamy Cunoosamy
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-19 (2019)
Abstract Background The airway epithelium is a major target tissue in respiratory infections, and its antiviral response is mainly orchestrated by the interferon regulatory factor-3 (IRF3), which subsequently induces type I (β) and III (λ) interfer
Externí odkaz:
https://doaj.org/article/37834a1f40794b25b512aab2c43f11ac
Autor:
Tia DiTommaso, Denny L Cottle, Helen B Pearson, Holger Schlüter, Pritinder Kaur, Patrick O Humbert, Ian M Smyth
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004706 (2014)
Keratins are cytoskeletal intermediate filament proteins that are increasingly being recognised for their diverse cellular functions. Here we report the consequences of germ line inactivation of Keratin 76 (Krt76) in mice. Homozygous disruption of th
Externí odkaz:
https://doaj.org/article/8f10fdad58e248f49215c890e550eb36