Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Holger Schlaszus"'
Autor:
Holger Schlaszus, Cornelia Zachskorn, Richard Meyermann, Perikles Simon, Michael Weller, Patrick N. Harter, Michel Mittelbronn, Frauke Röttger, Monika Winkels, Jens Schittenhelm
Publikováno v:
Histopathology. 58:739-749
Schittenhelm J, Simon P, Harter P N, Zachskorn C, Schlaszus H, Rottger F, Winkels M, Weller M, Meyermann R & Mittelbronn M (2011) Histopathology58, 739–749 CD133 expression is associated with small round blue cell tumour morphology in human central
Autor:
Richard Meyermann, Klaus Dietz, Ariane Schleich, Michel Mittelbronn, Holger Schlaszus, Manuel Stoll, Christian Loeffler
Publikováno v:
Neuropathology. 31:230-238
Despite the blood–brain barrier (BBB) the human CNS is continuously screened by blood-derived immunological cells. In certain brain areas the local BBB configuration grants passage of large molecules, whereas others are better shielded. We investig
Differential microglial regulation in the human spinal cord under normal and pathological conditions
Autor:
Richard Meyermann, Arne Warth, Michel Mittelbronn, Holger Schlaszus, Klaus Dietz, Manuel Stoll, Ariane Schleich, David Capper
Publikováno v:
Neuropathology and Applied Neurobiology. 32:650-661
As the primary intrinsic immune effector cells of the central nervous system, microglia are involved in virtually all pathological processes of the brain and spinal cord including inflammatory, neurodegenerative, traumatic, neoplastic and vascular di
Publikováno v:
Acta Neuropathologica. 109:393-399
Autosomal dominant optic atrophy (adOA) is the most prevalent hereditary optic neuropathy with moderate to severe visual field loss and loss of retinal ganglion cells. The majority of cases of adOA is associated with mutations in the OPA1 gene. North
Autor:
Jens, Schittenhelm, Perikles, Simon, Patrick N, Harter, Cornelia, Zachskorn, Holger, Schlaszus, Frauke, Röttger, Monika, Winkels, Michael, Weller, Richard, Meyermann, Michel, Mittelbronn
Publikováno v:
Histopathology. 58(5)
CD133 is considered to be a marker for brain tumour-initiating cells. However, most data on CD133 are derived from animal or in-vitro studies. The aim of this study was to characterize CD133 expression, and the distribution and morphological features
Autor:
Christian, Loeffler, Klaus, Dietz, Ariane, Schleich, Holger, Schlaszus, Manuel, Stoll, Richard, Meyermann, Michel, Mittelbronn
Publikováno v:
Neuropathology : official journal of the Japanese Society of Neuropathology. 31(3)
Despite the blood-brain barrier (BBB) the human CNS is continuously screened by blood-derived immunological cells. In certain brain areas the local BBB configuration grants passage of large molecules, whereas others are better shielded. We investigat
Autor:
Ghazaleh Tabatabai, Holger Schlaszus, Michel Mittelbronn, Perikles Simon, Caroline Herrmann, David Capper, Rudi Beschorner, Jens Schittenhelm, Richard Meyermann, Michael Weller
Publikováno v:
Neuropathology and applied neurobiology. 35(1)
Aims: Currently, clinical trials using WT1 (Wilms tumour gene) peptide vaccines are conducted in haematopoietic malignancies and solid cancers. Single reports showed that the Wilms tumour gene product WT1 is also expressed in astrocytic neoplasms. Ou
Autor:
David Capper, Perikles Simon, Benedikt Bunz, Ghazaleh Tabatabai, Wolfgang Wick, R. Becker, Holger Schlaszus, Klaus Dietz, Dirk Freudenstein, Michel Mittelbronn, R. Ajaaj, M. Weller, Axel S. Merseburger, Richard Meyermann, Benjamin Goeppert, F. Stubenvoll
Publikováno v:
Neuropathology and applied neurobiology. 33(3)
The erythropoietin receptor (EPO-R) is mainly known as a regulator of erythropoiesis. However, recent studies revealed that the EPO-R is not exclusively expressed in haematopoietic tissues but also in various cancer cell types and normal tissue such
Autor:
Christian Löffler, Holger Schlaszus, Jörg Wischhusen, Benjamin Goeppert, Michel Mittelbronn, Richard Meyermann, David Capper, Patrick N. Harter, Michael Weller, Ghazaleh Tabatabai, Ariane Schleich, Perikles Simon, Benedikt Bunz
Publikováno v:
Journal of neuroimmunology. 189(1-2)
HLA-E is a ligand for the immune-inhibitory NKG2A receptor expressed on NK and T cells. To investigate HLA-E expression and immune cell infiltration in human astrocytic tumors in vivo, we analyzed normal CNS controls and astrocytomas of all WHO grade
Autor:
Ariane Schleich, Holger Schlaszus, Rudi Beschorner, Perikles Simon, Klaus Dietz, Thai D. Nguyen, Michel Mittelbronn, Richard Meyermann
Publikováno v:
Applied immunohistochemistrymolecular morphology : AIMM. 14(4)
Immunohistochemical procedures constitute a high methodological value in both pathologic diagnostics and research. Staining quality depends on a large variety of interference factors. Primarily, background staining reduces the quality of evaluation b