Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Holger Lörchner"'
Autor:
Simon F. Merz, Sebastian Korste, Lea Bornemann, Lars Michel, Pia Stock, Anthony Squire, Camille Soun, Daniel R. Engel, Julia Detzer, Holger Lörchner, Dirk M. Hermann, Markus Kamler, Joachim Klode, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Gunzer, Matthias Totzeck
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Detailed characterization of cardiac damage following ischemia/reperfusion injury and detection of occurring inflammatory responses is important for the development of new therapeutic concepts. Here the authors present a method for the three-dimensio
Externí odkaz:
https://doaj.org/article/3e96cf3e564a4e068419e2da632f2557
Autor:
Simon F. Merz, Sebastian Korste, Lea Bornemann, Lars Michel, Pia Stock, Anthony Squire, Camille Soun, Daniel R. Engel, Julia Detzer, Holger Lörchner, Dirk M. Hermann, Markus Kamler, Joachim Klode, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Gunzer, Matthias Totzeck
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/d9923d29d593469cb22f223c62a1ff70
Autor:
Holger Lörchner, Juan M. Adrian-Segarra, Christian Waechter, Roxanne Wagner, Maria Elisa Góes, Nathalie Brachmann, Krishnamoorthy Sreenivasan, Astrid Wietelmann, Stefan Günther, Nicolas Doll, Thomas Braun, Jochen Pöling
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 353, p 353 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 353
International Journal of Molecular Sciences, Vol 23, Iss 353, p 353 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 353
Oncostatin M (OSM) and leukemia inhibitory factor (LIF) signaling protects the heart after myocardial infarction (MI). In mice, oncostatin M receptor (OSMR) and leukemia inhibitory factor receptor (LIFR) are selectively activated by the respective co
Autor:
Zoltán Giricz, András Makkos, Rolf Schreckenberg, Jochen Pöling, Holger Lörchner, Krisztina Kiss, Péter Bencsik, Thomas Braun, Rainer Schulz, Péter Ferdinandy, Klaus-Dieter Schlüter
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3359, p 3359 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 3359, p 3359 (2020)
Swiprosin-1 (EFhD2) is a molecule that triggers structural adaptation of isolated adult rat cardiomyocytes to cell culture conditions by initiating a process known as cell spreading. This process mimics central aspects of cardiac remodeling, as it oc
Autor:
Henning Warnecke, Jochen Pöling, Julia Detzer, Praveen Gajawada, Juan M. Adrian-Segarra, Holger Lörchner, Thomas Braun, Jennifer Kulhei, Hans W.M. Niessen, Stefan Günther, Yunlong Hou
Publikováno v:
Lörchner, H, Hou, Y, Adrian-Segarra, J M, Kulhei, J, Detzer, J, Günther, S, Gajawada, P, Warnecke, H, Niessen, H W, Pöling, J & Braun, T 2018, ' Reg proteins direct accumulation of functionally distinct macrophage subsets after myocardial infarction ', Cardiovascular Research, vol. 114, no. 12, pp. 1667-1679 . https://doi.org/10.1093/cvr/cvy126
Cardiovascular Research, 114(12), 1667-1679. Oxford University Press
Cardiovascular Research, 114(12), 1667-1679. Oxford University Press
Aims Myocardial infarction (MI) causes a massive increase of macrophages in the heart, which serve various non-redundant functions for cardiac repair. The identities of signals controlling recruitment of functionally distinct cardiac macrophages to s
Autor:
Julia Detzer, Matthias Totzeck, Dirk M. Hermann, Lea Bornemann, Tienush Rassaf, Simon F. Merz, Anthony Squire, Camille Soun, Ulrike B. Hendgen-Cotta, Lars Michel, Pia Stock, Daniel R. Engel, Holger Lörchner, Sebastian Korste, Markus Kamler, Joachim Klode, Matthias Gunzer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Nature Communications
Nature Communications
Cardioprotection by salvage of the infarct-affected myocardium is an unmet yet highly desired therapeutic goal. To develop new dedicated therapies, experimental myocardial ischemia/reperfusion (I/R) injury would require methods to simultaneously char
Publikováno v:
Journal of Visualized Experiments.
The goal of this protocol encompasses the design of chimeric proteins in which distinct regions of a protein are replaced by their corresponding sequences in a structurally similar protein, in order to determine the functional importance of these reg
Autor:
M. Adrian-Segarra, Praveen Gajawada, Yunlong Hou, Jochen Pöling, H. Warnecke, Holger Lörchner, Stefan Günther, Thomas Braun, T. Böttger
Publikováno v:
The Thoracic and Cardiovascular Surgeon.
Autor:
Anthony Squire, Pia Stock, Ulrike B. Hendgen-Cotta, Dirk M. Hermann, Julia Detzer, Lea Bornemann, Joachim Klode, Tienush Rassaf, Holger Lörchner, Markus Kamler, Simon F. Merz, Camille Soun, Sebastian Korste, Matthias Totzeck, Daniel R. Engel, Lars Michel, Matthias Gunzer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Cardioprotection by salvage of the infarct-affected myocardium is an unmet yet highly desired therapeutic goal. To develop new dedicated therapies, experimental myocardial ischemia/reperfusion (I/R) injury would require methods to simultaneously char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1e3931c8b29016c1a6726ca674918b
https://www.ncbi.nlm.nih.gov/pubmed/31127113
https://www.ncbi.nlm.nih.gov/pubmed/31127113
Autor:
Christoph B. Wiedenroth, Prakash Chelladurai, Leili Jafari, Werner Seeger, Soni Savai Pullamsetti, Thomas Braun, Manuel J. Richter, Christoph Liebetrau, Timm Bauer, Christian W. Hamm, Till Keller, Khodr Tello, Stefan Guth, Hossein Ardeschir Ghofrani, Sandra Voss, Holger Lörchner, Christian Troidl, Jakob Lorenz, Holger Nef, Eckhard Mayer, Steffen D. Kriechbaum, Jochen Pöling, Henning Gall, Stanislav Keranov, Oliver Dörr
Publikováno v:
European Respiratory Journal. 57:1901192
The aim of our study was to analyse the protein expression of cartilage intermediate layer protein (CILP)1 in a mouse model of right ventricular (RV) pressure overload and to evaluate CILP1 as a biomarker of cardiac remodelling and maladaptive RV fun