Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Holger Kraul"'
Publikováno v:
Pharmacogenetics. 2:227-233
A test designed to estimate the extent and rate of formation of 7-hydroxycoumarin by measuring the urinary excretion of the metabolite in humans after administering 5 mg coumarin was developed. Coumarin was rapidly metabolized after oral administrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93ace6eef4e3156c2a6c7df0d7d2bd8
https://doi.org/10.1097/00008571-199210000-00005
https://doi.org/10.1097/00008571-199210000-00005
Publikováno v:
Toxicology. 69:1-9
The influence of the known hepatotoxic agent, cerium (Ce) on the activity of liver microsomal monoxygenases, especially coumarin 7-hydroxylase (COH) was investigated in two inbred strains of male mice, DBA/2N and C57BL/6N. Ce was injected intravenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62182e4ba3247dec6aecf6937b31bc69
https://doi.org/10.1016/0300-483x(91)90148-t
https://doi.org/10.1016/0300-483x(91)90148-t
Autor:
Holger Kraul, Karl Hayduk
Publikováno v:
Journal of cardiovascular pharmacology. 34
Spirapril is a new angiotensin-converting enzyme (ACE) inhibitor. It is a prodrug with a resorption of about 50%. The active metabolite spiraprilat reaches maximal plasma concentration within 2-3 h after oral administration. Spirapril can be administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84511299b5be711e4bcfafda1a1e9ad
https://pubmed.ncbi.nlm.nih.gov/10499560
https://pubmed.ncbi.nlm.nih.gov/10499560
Autor:
Holger Kraul, Joachim Schmidt
Publikováno v:
Journal of cardiovascular pharmacology. 34
The efficacy and tolerability of spirapril were evaluated in a prospective, multicentre, post-marketing surveillance study on the treatment of arterial hypertension in 5000 patients, most of whom had received a single daily dose of 6 mg spirapril. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27cdd637f6de017812546148f471e3c
https://pubmed.ncbi.nlm.nih.gov/10499561
https://pubmed.ncbi.nlm.nih.gov/10499561