Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Holger Kneuper"'
Publikováno v:
Open Biology, Vol 14, Iss 8 (2024)
Successful colonization by the opportunistic pathogen Staphylococcus aureus depends on its ability to interact with other microorganisms. Staphylococcus aureus strains harbour a T7b subtype of type VII secretion system (T7SSb), a protein secretion sy
Externí odkaz:
https://doaj.org/article/e7e60f5eb285483daf48771a66a32a2c
Autor:
Fatima R, Ulhuq, Margarida C, Gomes, Gina M, Duggan, Manman, Guo, Chriselle, Mendonca, Grant, Buchanan, James D, Chalmers, Zhenping, Cao, Holger, Kneuper, Sarah, Murdoch, Sarah, Thomson, Henrik, Strahl, Matthias, Trost, Serge, Mostowy, Tracy, Palmer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Staphylococcus aureus, a human commensal organism that asymptomatically colonizes the nares, is capable of causing serious disease following breach of the mucosal barrier. S. aureus strains encode a type VII secretion system that is requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ab49dc5ecb3e6db9ebe35af39f41ac0
https://pubmed.ncbi.nlm.nih.gov/32769205
https://pubmed.ncbi.nlm.nih.gov/32769205
Publikováno v:
Microbiology
The Type VII protein secretion system (T7SS) is found in actinobacteria and firmicutes, and plays important roles in virulence and interbacterial competition. A membrane-bound ATPase protein, EssC in Staphylococcus aureus, lies at the heart of the se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39201526dcbfe4aee9dd2d5ed1bbd5f
http://europepmc.org/articles/PMC5994694
http://europepmc.org/articles/PMC5994694
Publikováno v:
Microbiology
Salmonella enterica serovar Typhimurium is a Gram-negative bacterium with a flexible respiratory capability. Under anaerobic conditions, S. enterica can utilize a range of terminal electron acceptors, including selenate, to sustain respiratory electr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec4c6998012a79ca5e3bb109a0d022d
http://europepmc.org/articles/PMC5203670
http://europepmc.org/articles/PMC5203670
EssC: domain structures inform on the elusive translocation channel in the Type VII secretion system
Autor:
William N. Hunter, Jillian J. Money, Martin Zoltner, Holger Kneuper, Wui M.A.V. Ng, Tracy Palmer, Paul K. Fyfe
Publikováno v:
Biochemical Journal
'Biochemical Journal ', vol: 473, pages: 1941-1952 (2016)
'Biochemical Journal ', vol: 473, pages: 1941-1952 (2016)
Structural dissection of EssC, a membrane-bound component of the bacterial Type VII secretion system, reveals two β-sandwich domains at the N-terminus and two ATPase domains at the C-terminus. A structure for the potential pore of the secretion syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2489b0967e08722e67ce94f7071f82b6
https://doi.org/10.1042/bcj20160257
https://doi.org/10.1042/bcj20160257
Autor:
Henrik Strahl, Chriselle Mendonca, Margarida C. Gomes, Serge Mostowy, Matthias Trost, Zhenping Cao, Sarah Murdoch, James D. Chalmers, Fatima R. Ulhuq, Manman Guo, Grant Buchanan, Holger Kneuper, Sarah Thomson, Gina Duggan, Tracy Palmer
The type VII protein secretion system (T7SS) is conserved across Staphylococcus aureus strains and plays important roles in virulence and interbacterial competition. To date only one T7SS substrate protein, encoded in a subset of S. aureus genomes, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3b37316aaba1f7a00736e62e8bbaf16
https://doi.org/10.1101/443630
https://doi.org/10.1101/443630
Autor:
Erik Hjerde, Daniela Alferes de Lima, Maria Guillermina Casabona, Matthew T. G. Holden, Martin Zoltner, Tracy Palmer, Catriona P. Harkins, Holger Kneuper
TheStaphylococcus aureusType VII protein secretion system (T7SS) plays important roles in virulence and intra-species competition. Here we show that the T7SS in strain RN6390 is activated by supplementing the growth medium with hemoglobin, and its co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a71453a5c3332ec75a360a22c5d3ff
https://doi.org/10.1101/145433
https://doi.org/10.1101/145433
Autor:
Felicity Alcock, Susan M. Lea, Qi Huang, Justin C. Deme, Sarah E. Rollauer, Ben C. Berks, Tracy Palmer, Holger Kneuper
Publikováno v:
Proceedings of the National Academy of Sciences. 114
The twin-arginine protein translocation (Tat) system mediates transport of folded proteins across the cytoplasmic membrane of bacteria and the thylakoid membrane of chloroplasts. The Tat system of Escherichia coli is made up of TatA, TatB, and TatC c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8577f12f73d9110434dbd48789f60b2
https://doi.org/10.1073/pnas.1615056114
https://doi.org/10.1073/pnas.1615056114
Autor:
William N. Hunter, James D. Chalmers, Zhen Ping Cao, Magdalena M. van der Kooi-Pol, Jan Maarten van Dijl, James S. Cargill, Robert P. Ryan, Tracy Palmer, Kate B. Twomey, Martin Zoltner, Holger Kneuper, Franziska Jäger
Publikováno v:
Molecular Microbiology. 93:928-943
The Type VII protein secretion system, found in Gram-positive bacteria, secretes small proteins, containing a conserved W-x-G amino acid sequence motif, to the growth medium. Staphylococcus aureus has a conserved Type VII secretion system, termed Ess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a612faeb2e865c07f68c6572b8f2d10
https://doi.org/10.1111/mmi.12707
https://doi.org/10.1111/mmi.12707
Publikováno v:
Nature Microbiology. 2
The type VII protein secretion system (T7SS) plays a critical role in the virulence of human pathogens including Mycobacterium tuberculosis and Staphylococcus aureus. Here we report that the S. aureus T7SS secretes a large nuclease toxin, EsaD. The t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865f23f2b348022b8e5056e72286e566
https://doi.org/10.1038/nmicrobiol.2016.183
https://doi.org/10.1038/nmicrobiol.2016.183