Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Holger Klammer"'
Publikováno v:
International Journal of Radiation Biology. 94:719-726
A well-known phenomenon in the field of radiation biology is that cells exposed to ionizing radiation (IR) (targeted cells) can induce in non-irradiated (non-targeted), bystander cells effects reminiscent of DNA damage responses (DDR) normally expect
Autor:
Holger Klammer, George Iliakis
Publikováno v:
International Journal of Radiation Biology. 88:777-780
This investigation addresses the question of whether serum constituents have a modulating effect on the induction of bystander effects. It was carried out as part of an inter-laboratory comparison-exercise within the European Union-integrated project
Publikováno v:
International Journal of Radiation Biology. 88:720-726
Radiation-induced adaptive response (AR) is a phenomenon of increased radioresistance mediated by a low priming dose of ionizing radiation (IR) applied prior to a higher challenging dose. We have previously shown that in mouse-embryo fibroblasts (MEF
Publikováno v:
Cancer Research. 70:8498-8506
Adaptive response (AR) is a term describing resistance to ionizing radiation–induced killing or formation of aberrant chromosomes that is mediated by pre-exposure to low ionizing radiation doses. The mechanism of AR remains elusive. Because cell ki
Publikováno v:
Archives of Toxicology. 80:656-661
The tetrahydroxylated biphenyl-ketone 2,2',4,4'-tetrahydroxybenzophenone (BP2), one of twelve benzophenone-derived UV-filters, is used in cosmetic products and in packaging materials to protect these products from light induced damage. Recently publi
Publikováno v:
Toxicology. 215:90-96
Sun protection products contain a variety of UV-filters, among others, octyl-methoxycinnamate (OMC). Recently, an uterotrophic effect in immature rats has been reported, indicating that OMC might have estrogenic properties and thus is an endocrine ac
Publikováno v:
Toxicology. 205:123-130
The estrogen receptors (ERs) are members of a super family of ligand-activated transcription factors mediating estrogenic responses. A close functional kinship was found for the structurally related estrogen receptor-related receptor1 (ERR1), a const
Publikováno v:
Cancer letters. 356(1)
It is becoming increasingly clear that cells exposed to ionizing radiation (IR) and other genotoxic agents (targeted cells) can communicate their DNA damage response (DDR) status to cells that have not been directly irradiated (bystander cells). The
Purpose The backup pathway of nonhomologous end joining (B-NHEJ) enables cells to process DNA double-strand breaks (DSBs) when the DNA-PK–dependent pathway of NHEJ (D-NHEJ) is compromised. Our previous results show marked reduction in the activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32812669f1e617801ce1276401b13dfe
https://www.ncbi.nlm.nih.gov/pubmed/20950945
https://www.ncbi.nlm.nih.gov/pubmed/20950945
Publikováno v:
Toxicology. 245(1-2)
Twelve derivatives of benzophenone (BP1-BP12) are widely used as UV-screens to protect industrial products from light induced damage. There is growing public concern about industrially produced chemicals that might interfere with hormonal signalling