Diagnostic error as a result of drug-laboratory test interactions

Autor: Wytze P. Oosterhuis, Heleen van der Sijs, Albert J de Graaf, Wilhelmine P.H.G. Verboeket-van de Venne, Holger K. de Wolf, Jasmijn A. van Balveren, Ron Kusters, Rein M.J. Hoedemakers, Lale Erdem-Eraslan, Rolf J Verheul, Ruben E A Musson, Annemarieke E. Loot, Martin P. Schuijt

Publikováno v: Diagnosis, 6(1), 69-71. De Gruyter

Background Knowledge of possible drug-laboratory test interactions (DLTIs) is important for the interpretation of laboratory test results. Test results may be affected by physiological or analytical drug effects. Failure to recognize these interactio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de634b35aa39e6587340dde3c229dbcd
https://doi.org/10.1515/dx-2018-0098

Biodegradable Poly(2-Dimethylamino Ethylamino)Phosphazene for In Vivo Gene Delivery to Tumor Cells. Effect of Polymer Molecular Weight

Autor: Mies J. van Steenbergen, Wim E. Hennink, Gert Storm, Cor J. Snel, Holger K. de Wolf, Marcel H.A.M. Fens, Markus de Raad

Publikováno v: Pharmaceutical Research

Purpose Previously, we have shown that complexes of plasmid DNA with the biodegradable polymer poly(2-dimethylamino ethylamino)phosphazene (p(DMAEA)-ppz) mediated tumor selective gene expression after intravenous administration in mice. In this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd5cd048e7d649552330b80b1f72a7c
https://doi.org/10.1007/s11095-007-9299-z

In vivo tumor transfection mediated by polyplexes based on biodegradable poly(DMAEA)-phosphazene

Autor: Cor J. Snel, C. Oussoren, Jordy Luten, Holger K. de Wolf, Wim E. Hennink, Gert Storm

Publikováno v: Journal of Controlled Release. 109:275-287

In recent years, increasing interest is being paid to the design of transfectants based on non-toxic and biodegradable polymers for gene therapy purposes. We recently reported on a novel, biodegradable polymer, poly(2-dimethylamino ethylamino)phospha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e0a718286b250ebc6589d82c67e3cb
https://doi.org/10.1016/j.jconrel.2005.05.030

Bioreducible poly(amido amine)s for gene delivery to ovarian cancer cells

Autor: C. Lin, Jan Feijen, Martin C. Lok, Zhiyuan Zhong, W.E. Hennink, Holger K. de Wolf, Johannes F.J. Engbersen

Publikováno v: ISSUE=10;STARTPAGE=94;ENDPAGE=97;TITLE=10th European Symposium on Controlled Drug Delivery, ESCDD 2008
Journal of controlled release, 132(3), e9-e10. Elsevier

Bioreducible poly(amido amine)s (SS-PAAs) with different groups in the side chain were evaluated for gene delivery to ovarian cancer cells, both in vitro and in vivo after intraperitoneal administration in mice bearing an ovarian cancer xenograft. Po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98998ee8d21126bacd0cdab4dd14f882
https://research.utwente.nl/en/publications/bioreducible-polyamido-amines-for-gene-delivery-to-ovarian-cancer-cells(3f51e78a-fc18-4ec5-b44a-3d6014c974b0).html

Effect of cationic carriers on the pharmacokinetics and tumor localization of nucleic acids after intravenous administration

Autor: Raymond M. Schiffelers, Wim E. Hennink, Cor J. Snel, Gert Storm, Holger K. de Wolf, F.J. Verbaan

Publikováno v: International journal of pharmaceutics. 331(2)

Nucleic acid based therapeutics are currently being studied for their application in cancer therapy. In this study, the effect of different cationic delivery systems on the circulation kinetics, tumor localization, and tissue distribution of short in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75540bab27d56f8154e1737288f9fe18
https://pubmed.ncbi.nlm.nih.gov/17134859