Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Holger Hannemann"'
Autor:
Stefan W. Metz, Ashlie Thomas, Laura White, Mark Stoops, Markus Corten, Holger Hannemann, Aravinda M. de Silva
Publikováno v:
Virology Journal, Vol 15, Iss 1, Pp 1-10 (2018)
Abstract Background The 4 dengue serotypes (DENV) are mosquito-borne pathogens that are associated with severe hemorrhagic disease. DENV particles have a lipid bilayer envelope that anchors two membrane glycoproteins prM and E. Two E-protein monomers
Externí odkaz:
https://doaj.org/article/cec765ff6cab4d9cb974eae17e399d64
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e93305 (2014)
Disease caused by dengue virus is a global health concern with up to 390 million individuals infected annually worldwide. There are no vaccines or antiviral compounds available to either prevent or treat dengue disease which may be fatal. To increase
Externí odkaz:
https://doaj.org/article/96d52a10841d46e397f7a44441e5937a
Autor:
Holger Hannemann
Publikováno v:
Drug Discovery Today. 25:1026-1033
RNA viruses can cause severe diseases such as dengue, Lassa, chikungunya and Ebola. Many of these viruses can only be propagated under high containment levels, necessitating the development of low containment surrogate systems such as subgenomic repl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f7105bd6250f67bd1c1a2cb2403cb0
https://doi.org/10.1016/j.drudis.2020.03.010
https://doi.org/10.1016/j.drudis.2020.03.010
Autor:
Natacha Teissier, Deborah Duricka, Elizabeth M. Keithley, Elizabeth A. Fortunato, Emmerentia Marx, Man I Kuan, Liliana Gabrielli, Hannah K Jaeger, Holger Hannemann, Maria Paola Bonasoni, John M. O'Dowd, Onesmo B. Balemba
Publikováno v:
J Virol
In 2000, we reported that human cytomegalovirus (HCMV) induced specific damage on chromosome 1. The capacity of the virus to induce DNA breaks indicated potent interaction between viral proteins and these loci. We have fine mapped the 1q42 breaksite.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcc546670777a0590d59acda176a65f
https://doi.org/10.1128/jvi.01506-20
https://doi.org/10.1128/jvi.01506-20
Autor:
Ashlie Thomas, Mark Corten, Holger Hannemann, Aravinda M. de Silva, Laura J. White, Mark Stoops, Stefan W. Metz
Publikováno v:
Virology Journal
Virology Journal, Vol 15, Iss 1, Pp 1-10 (2018)
Virology Journal, Vol 15, Iss 1, Pp 1-10 (2018)
Background The 4 dengue serotypes (DENV) are mosquito-borne pathogens that are associated with severe hemorrhagic disease. DENV particles have a lipid bilayer envelope that anchors two membrane glycoproteins prM and E. Two E-protein monomers form hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f33af4f988b5b921edff3db1ccace1
http://europepmc.org/articles/PMC5879749
http://europepmc.org/articles/PMC5879749
Autor:
Antje Biesemeier, Brad N. Taylor, Klaus Schröppel, Miriam Sehnal, Holger Hannemann, Martin Röllinghoff, Anja Schweizer
Publikováno v:
Infection and Immunity. 73:7061-7063
SAP7 of Candida albicans is induced after vaginal infection of mice. Conversely, virulence during vaginal infection was not affected in a Δ sap7/ Δ sap7 mutant strain. Only a partial virulence phenotype was detectable after intravenous injection. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e5cdcc24f30f6ba2e95b449ced9dec
https://doi.org/10.1128/iai.73.10.7061-7063.2005
https://doi.org/10.1128/iai.73.10.7061-7063.2005
Autor:
Po-Yu Sung, Jim M Bird, Han-Chen Chiu, Siew Pheng Lim, Andrew D. Davidson, Holger Hannemann, Amjad Yousuf
Publikováno v:
The Journal of biological chemistry. 288(31)
The four serotypes of dengue virus (DENV-1 to -4) cause the most important arthropod-borne viral disease of humans. DENV non-structural protein 5 (NS5) contains enzymatic activities required for capping and replication of the viral RNA genome that oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32472a3acb532b737f71d5735400041
https://pubmed.ncbi.nlm.nih.gov/23770669
https://pubmed.ncbi.nlm.nih.gov/23770669
Autor:
Elizabeth A. Fortunato, Min-Hua Luo, Amit S. Kulkarni, John M. O'Dowd, Holger Hannemann, Philip H. Schwartz
Publikováno v:
Journal of virology. 84(7)
Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects, largely manifested as central nervous system (CNS) disorders. The principal site of manifestations in the mouse model is the fetal brain's neural progenitor cell (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c7d78ca1b6372338fa93242bd13eac
https://pubmed.ncbi.nlm.nih.gov/20071566
https://pubmed.ncbi.nlm.nih.gov/20071566
Publikováno v:
Journal of virology. 83(9)
Human cytomegalovirus (HCMV) is a common cause of morbidity and mortality in immunocompromised and immunosuppressed individuals. During infection, HCMV is known to employ host transcription factors to facilitate viral gene expression. To further unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f514526073e4a78fceab27fed037cd
https://pubmed.ncbi.nlm.nih.gov/19224996
https://pubmed.ncbi.nlm.nih.gov/19224996