Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Holger Fuchs"'
Autor:
Hans-Joachim Wilke, Holger Fuchs, Karin Benz, Juergen Mollenhauer, Christoph Gaissmaier, Frank Heuer, Cornelia Neidlinger-Wilke
Publikováno v:
Gels, Vol 10, Iss 4, p 269 (2024)
For autologous-disc-derived chondrocyte transplantation (ADCT) a transglutaminase crosslinked gelatine gel and an albumin hyaluronic acid gel, crosslinked with bis-thio-polyethylene glycol, were injected through a syringe into a degenerated intervert
Externí odkaz:
https://doaj.org/article/d9b102b81eec47a98531bffea9534f1b
Autor:
Kolja Becker, Carina M. Weigelt, Holger Fuchs, Coralie Viollet, Werner Rust, Hannah Wyatt, Jochen Huber, Thorsten Lamla, Francesc Fernandez-Albert, Eric Simon, Nina Zippel, Remko A. Bakker, Holger Klein, Norbert H. Redemann
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract Retinopathies are multifactorial diseases with complex pathologies that eventually lead to vision loss. Animal models facilitate the understanding of the pathophysiology and identification of novel treatment options. However, each animal mod
Externí odkaz:
https://doaj.org/article/6aaa2e0a328d459892cb845548a66e42
Autor:
Lin-Zhi Chen, David Roos, Elsy Philip, Emily G. Werth, Stephanie Kostuk, Hongbin Yu, Holger Fuchs
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 193 (2024)
BI-X, a therapeutic protein under development for the treatment of human ocular disease via intravitreal administration, binds to its therapeutic targets and endogenous albumin in the vitreous humor. A monkey ocular pharmacokinetic (PK) study followi
Externí odkaz:
https://doaj.org/article/7a011e49b1bc40a7b8551599e66b1f2b
Autor:
Cecile Lebon, Heike Neubauer, Marianne Berdugo, Kimberley Delaunay, Elke Markert, Kolja Becker, Katja S. Baum-Kroker, Jürgen Prestle, Holger Fuchs, Remko A. Bakker, Francine Behar-Cohen
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1105 (2021)
Rho-associated kinase (ROCK) activation was shown to contribute to microvascular closure, retinal hypoxia, and to retinal pigment epithelium (RPE) barrier disruption in a rat model of diabetic retinopathy. Fasudil, a clinically approved ROCK inhibito
Externí odkaz:
https://doaj.org/article/1ac4a18e45a64c96a8cacd785255ca9e
Autor:
Lyubov Chaykovska, Karoline von Websky, Jan Rahnenführer, Markus Alter, Susi Heiden, Holger Fuchs, Frank Runge, Thomas Klein, Berthold Hocher
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27861 (2011)
BACKGROUND: Uremic cardiomyopathy contributes substantially to mortality in chronic kidney disease (CKD) patients. Glucagon-like peptide-1 (GLP-1) may improve cardiac function, but is mainly degraded by dipeptidyl peptidase-4 (DPP-4). METHODOLOGY/PRI
Externí odkaz:
https://doaj.org/article/4e4526f9dc6a4249a3ac5af61f79976c
Autor:
Hina Takeuchi, Masayoshi Suzuki, Ryohei Goto, Kenta Tezuka, Holger Fuchs, Naoki Ishiguro, Tetsuya Terasaki, Clemens Braun, Yasuo Uchida
Publikováno v:
Pharmaceutical Research. 39:1393-1413
The purpose of the present study was to quantitatively determine the expression of transporters, receptors and tight junction molecules at the blood-arachnoid barrier (BAB) and blood-spinal cord barrier (BSCB) in cervical, thoracic and lumbar spines
Publikováno v:
Die Wirbelsäule. :180-183
ZusammenfassungPharyngo-ösophageale Perforationen [PEP] sind eine sehr seltene (0,02 -1,52%) 1 jedoch lebensgefährliche Komplikation (Mortalität 16 – 50%) 2 nach anteriorer zervikaler Dekompression und Fusion. Die therapeutischen Optionen unterl
Autor:
Yasuo Uchida, Hina Takeuchi, Ryohei Goto, Clemens Braun, Holger Fuchs, Naoki Ishiguro, Masaki Takao, Mitsutoshi Tano, Tetsuya Terasaki
Publikováno v:
Journal of neurochemistryREFERENCES. 161(2)
The purpose of this study was to elucidate the absolute abundance of transporters, enzymes, receptors, and tight junction and marker proteins at human blood-arachnoid barrier (BAB) and compare with those of dogs and pigs. Protein expression levels in
Autor:
Carina M, Weigelt, Nina, Zippel, Holger, Fuchs, Anna-Kaisa, Rimpelä, Tanja, Schönberger, Birgit, Stierstorfer, Remko A, Bakker, Norbert H, Redemann
Publikováno v:
Translational Vision Science & Technology. 11:18
Inflammation is implicated in the etiology of diverse retinopathies including uveitis, age-related macular degeneration or diabetic retinopathy. Tumor necrosis factor alpha (TNF-α) is a well-known proinflammatory cytokine that is described as a biom
Autor:
Holger Fuchs, Kolja Becker, Katja S. Baum-Kroker, Remko A. Bakker, Francine Behar-Cohen, Marianne Berdugo, Heike Neubauer, Kimberley Delaunay, Cecile Lebon, Elke Markert, Jürgen Prestle
Publikováno v:
Pharmaceutics
Pharmaceutics, MDPI, 2021, 13 (8), pp.1105. ⟨10.3390/pharmaceutics13081105⟩
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1105, p 1105 (2021)
Pharmaceutics, MDPI, 2021, 13 (8), pp.1105. ⟨10.3390/pharmaceutics13081105⟩
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1105, p 1105 (2021)
International audience; Rho-associated kinase (ROCK) activation was shown to contribute to microvascular closure, retinal hypoxia, and to retinal pigment epithelium (RPE) barrier disruption in a rat model of diabetic retinopathy. Fasudil, a clinicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0ef41a8b39de0b58e05652fcf83e73
https://hal.sorbonne-universite.fr/hal-03352397/document
https://hal.sorbonne-universite.fr/hal-03352397/document