High-intensity interval training in patients with glaucoma (HIT-GLAUCOMA): protocol for a multicenter randomized controlled exercise trial

Autor: Jan Van Eijgen, Valentin Schuhmann, Emma-Liina Fingerroos, Marie Renier, Holger Burchert, Julia Maria Kröpfl, Amaryllis Van Craenenbroeck, Véronique Cornelissen, Konstantin Gugleta, Ingeborg Stalmans, Henner Hanssen

Publikováno v: Frontiers in Physiology, Vol 15 (2024)

BackgroundGlaucoma stands as a prominent global cause of irreversible blindness and the primary treatment approach involves reducing intraocular pressure (IOP). However, around one-third of patients exhibit disease progression despite effective IOP r

Externí odkaz: https://doaj.org/article/563b54ce02704e028079d1e59d3261d4

Effect of moderate to high intensity aerobic exercise on blood pressure in young adults: The TEPHRA open, two-arm, parallel superiority randomized clinical trial

Autor: Wilby Williamson, Adam James Lewandowski, Odaro John Huckstep, Winok Lapidaire, Alexander Ooms, Cheryl Tan, Afifah Mohamed, Maryam Alsharqi, Mariane Bertagnolli, William Woodward, Cameron Dockerill, Annabelle McCourt, Yvonne Kenworthy, Holger Burchert, Aiden Doherty, Julia Newton, Henner Hanssen, John Kennedy Cruickshank, Richard McManus, Jane Holmes, Chen Ji, Sharon Love, Elena Frangou, Colin Everett, Melvyn Hillsdon, Helen Dawes, Charlie Foster, Paul Leeson

Publikováno v: EClinicalMedicine, Vol 48, Iss , Pp 101445- (2022)

Summary: Background: Exercise is advised for young adults with elevated blood pressure, but no trials have investigated efficacy at this age. We aimed to determine whether aerobic exercise, self-monitoring and motivational coaching lowers blood press

Externí odkaz: https://doaj.org/article/6d71a7cdabcb4569a4825d7576d50a0a

Aerobic Exercise Training Response in Preterm-Born Young Adults with Elevated Blood Pressure and Stage 1 Hypertension: A Randomized Clinical Trial

Autor: Holger Burchert, Winok Lapidaire, Wilby Williamson, Annabelle McCourt, Cameron Dockerill, William Woodward, Cheryl M. J. Tan, Mariane Bertagnolli, Afifah Mohamed, Maryam Alsharqi, Henner Hanssen, Odaro J. Huckstep, Paul Leeson, Adam J. Lewandowski

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 207:1227-1236

Premature birth is an independent predictor of long-term cardiovascular risk. Individuals affected are reported to have a lower rate of oxygen consumption at peak exercise intensity and at ventilatory anaerobic threshold, but little is known about th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f9a7c8755ffe1c3c40e53d9aee30b3
https://doi.org/10.1164/rccm.202205-0858oc

Impaired myocardial reserve underlies reduced exercise capacity and heart rate recovery in preterm-born young adults

Autor: Kenny McCormick, Wilby Williamson, Odaro J Huckstep, Paul Leeson, Cheryl M.J. Tan, Afifah Mohamed, Linda Arnold, Adam J. Lewandowski, Henner Hanssen, Mariane Bertagnolli, F Telles, Holger Burchert

Publikováno v: European Heart Journal - Cardiovascular Imaging. 22:572-580

Aims We tested the hypothesis that the known reduction in myocardial functional reserve in preterm-born young adults is an independent predictor of exercise capacity (peak VO2) and heart rate recovery (HRR). Methods and results We recruited 101 normo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667db8fb580d9caa4fd05f44b5c08155
https://doi.org/10.1093/ehjci/jeaa060

Multimodality Imaging Demonstrates Reduced Right-Ventricular Function Independent of Pulmonary Physiology in Moderately Preterm-Born Adults

Autor: Katie Suriano, Adam J. Lewandowski, Pablo Lamata, Stefan Neubauer, Odaro J Huckstep, Paul Leeson, Philip T. Levy, Jane M Francis, Wilby Williamson, C Monteiro, Joana Leal Pelado, M Alsharqi, Afifah Mohamed, Cheryl M.J. Tan, Holger Burchert

Publikováno v: Jacc. Cardiovascular Imaging
Mohamed, A, Lamata, P, Williamson, W, Alsharqi, M, Tan, C M J, Burchert, H, Huckstep, O J, Suriano, K, Francis, J M, Pelado, J L, Monteiro, C, Neubauer, S, Levy, P T, Leeson, P & Lewandowski, A J 2020, ' Multimodality Imaging Demonstrates Reduced Right-Ventricular Function Independent of Pulmonary Physiology in Moderately Preterm-Born Adults ', JACC. Cardiovascular imaging, vol. 13, no. 9, pp. 2046-2048 . https://doi.org/10.1016/j.jcmg.2020.03.016

Preterm-born individuals have altered right-ventricular (RV) structure and function in young adulthood ([1][1]). To what extent the pulmonary circulation impacts these findings remains largely unknown. However, unlike RV changes that are apparent acr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd5ad04e7d583b09f585cef364b31b7
http://europepmc.org/articles/PMC7477490