Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Holger Babbe"'
Publikováno v:
Molecular and Cellular Biology. 27:1947-1959
Bloom's syndrome is a genetic disorder characterized by increased incidence of cancer and an immunodeficiency of unknown origin. The BLM gene mutated in Bloom's syndrome encodes a DNA helicase involved in the maintenance of genomic integrity. To expl
Autor:
Katherina Siewert, Hartmut Wekerle, Latika Bhonsle-Deeng, Klaus Dornmair, Eduardo Beltrán, Wakiro Sato, Thomas Misgeld, David-Axel Laplaud, Geraldine Rühl, Stephan Schmidt, Holger Babbe, Markus Moser, Reinhard Hohlfeld, Peter Engerer, Judy K.M. Ng, Wolfgang E. F. Klinkert, Kathrin Held
Publikováno v:
Neurology Neuroimmunology & Neuroinflammation
Neurology Neuroimmunology & Neuroinflammation, 2015, 2 (4), pp.e107. ⟨10.1212/NXI.0000000000000107⟩
Neurology Neuroimmunology & Neuroinflammation, American Academy of neurology, 2015, 2 (4), pp.e107. ⟨10.1212/NXI.0000000000000107⟩
Neurology® Neuroimmunology & Neuroinflammation
Neurology 2(4), e107 (2015). doi:10.1212/NXI.0000000000000107
Neurology Neuroimmunology & Neuroinflammation, 2015, 2 (4), pp.e107. ⟨10.1212/NXI.0000000000000107⟩
Neurology Neuroimmunology & Neuroinflammation, American Academy of neurology, 2015, 2 (4), pp.e107. ⟨10.1212/NXI.0000000000000107⟩
Neurology® Neuroimmunology & Neuroinflammation
Neurology 2(4), e107 (2015). doi:10.1212/NXI.0000000000000107
OBJECTIVES: To characterize phenotypes of T cells that accumulated in multiple sclerosis (MS) lesions, to compare the lesional T-cell receptor (TCR) repertoire of T-cell subsets to peripheral blood, and to identify paired alpha and beta chains from s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d4eecb9c03a95ba1f8f61c352e25e6
https://hdl.handle.net/11858/00-001M-0000-002A-1777-B11858/00-001M-0000-002A-1779-7
https://hdl.handle.net/11858/00-001M-0000-002A-1777-B11858/00-001M-0000-002A-1779-7
Autor:
Monika Hofbauer, Axel Roers, Holger Babbe, Reinhard Hohlfeld, Hartmut Wekerle, Norbert Goebels, Solveigh Wiesener, Klaus Dornmair
Publikováno v:
Proceedings of the National Academy of Sciences. 100:4090-4095
Clonal expansions of CD8+ T cells have been identified in muscle and blood of polymyositis patients by PCR techniques, including T cell receptor (TCR) complementarity-determining region (CDR)3 length analysis (spectratyping). To examine a possible pa
Autor:
Michael Friese, Rivka Ravid, Ari Waisman, Reinhard Hohlfeld, Klaus Rajewsky, Stephan Schmidt, Hans Lassmann, Holger Babbe, Martina Deckert, Norbert Goebels, Roland Schröder, Axel Roers
Publikováno v:
The Journal of Experimental Medicine
Clonal composition and T cell receptor (TCR) repertoire of CD4(+) and CD8(+) T cells infiltrating actively demyelinating multiple sclerosis (MS) lesions were determined with unprecedented resolution at the level of single cells. Individual CD4(+) or
Autor:
Michael Reth, Philip Leder, Jennifer McMenamin, Scott J. Rodig, Holger Babbe, Elias Hobeika, Jing Wang
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 182(1)
The RecQ family helicase BLM is critically involved in the maintenance of genomic stability, and BLM mutation causes the heritable disorder Bloom’s syndrome. Affected individuals suffer from a predisposition to a multitude of cancer types and an il
Publikováno v:
Molecular and cellular biology. 26(17)
Bloom's syndrome (BS) is a genetic disorder characterized cellularly by increases in sister chromatid exchanges (SCEs) and numbers of micronuclei. BS is caused by mutation in the BLM DNA helicase gene and involves a greatly enhanced risk of developin
Autor:
Charlene Manning, Philip Leder, Marcelo J. Berardi, Valeria R. Fantin, Montserrat V. Michelman, Holger Babbe
Publikováno v:
Cancer research. 65(15)
The HER-2 oncoprotein is commonly overexpressed in a variety of human malignancies and has become an attractive antitumor target. A number of strategies to inhibit the HER-2 receptor tyrosine kinase are currently the focus of intensive preclinical an
Autor:
Axel Roers, Norbert Goebels, Holger Babbe, Reinhard Hohlfeld, Stephan Schmidt, Klaus Dornmair, Klaus Rajewsky, Christian Skulina, Hartmut Wekerle
We surveyed the T cell receptor repertoire in three separate compartments (brain, cerebrospinal fluid, and blood) of two multiple sclerosis patients who initially had diagnostic brain biopsies to clarify their unusual clinical presentation but were s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e181c1046c048c096ec3ba97d474c55b
https://europepmc.org/articles/PMC356967/
https://europepmc.org/articles/PMC356967/