Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Holger Sellner"'
Autor:
Maura A Crowley, Donita L Garland, Holger Sellner, Angela Banks, Lin Fan, Tomas Rejtar, Natasha Buchanan, Omar Delgado, Yong Yao Xu, Sandra Jose, Christopher M Adams, Muneto Mogi, Karen Wang, Chad E Bigelow, Stephen Poor, Karen Anderson, Bruce D Jaffee, Ganesh Prasanna, Cynthia Grosskreutz, Rosario Fernandez-Godino, Eric A Pierce, Thaddeus P Dryja, Sha-Mei Liao
Publikováno v:
Human Molecular Genetics. 32:204-217
EFEMP1 R345W is a dominant mutation causing Doyne honeycomb retinal dystrophy/malattia leventinese (DHRD/ML), a rare blinding disease with clinical pathology similar to age-related macular degeneration (AMD). Aged Efemp1 R345W/R345W knock-in mice (Ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec58b40ea8387ba6f2edc6bd8b972d3
https://doi.org/10.1093/hmg/ddac187
https://doi.org/10.1093/hmg/ddac187
Autor:
Holger Sellner, Emilie Chapeau, Pascal Furet, Markus Voegtle, Bahaa Salem, Mickaël Le Douget, Vincent Bordas, Jean‐Marc Groell, Anne‐Laure Le Goff, Christine Rouzet, Thomas Wietlisbach, Thomas Zimmermann, Joseph McKenna, Cara E. Brocklehurst, Patrick Chène, Markus Wartmann, Clemens Scheufler, Joerg Kallen, Gareth Williams, Stephanie Harlfinger, Martin Traebert, Bérengère M. Dumotier, Tobias Schmelzle, Nicolas Soldermann
Publikováno v:
ChemMedChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87689f9fe496e8ff4e8b8008d72b261f
https://doi.org/10.1002/cmdc.202300051
https://doi.org/10.1002/cmdc.202300051
Autor:
Brahm H. Segal, Emese Zsiros, Michael B. Yaffe, Kunle Odunsi, Kirsten B. Moysich, Kevin H. Eng, James A. Lederer, Sanjay Ram, Steven M. Holland, Jörg Eder, Holger Sellner, Anna Schubart, Viviana P. Ferreira, Lee-Ann H. Allen, Ilse Jongerius, Taco W. Kuijpers, Sora Suzuki, Mieke C. Brouwer, Cathelijn E.M. Aarts, Ivy L. Debreceni, Stephanie L. Silva-Del Toro, Kaitlyn Howard, Jason Ricciuti, ANM Nazmul H. Khan, Kelly L. Singel, Thejaswini Giridharan, Tiffany R. Emmons
Supplementary Tables 1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a13f6bea6ac0d91539043db8f72237
https://doi.org/10.1158/2326-6066.22543195
https://doi.org/10.1158/2326-6066.22543195
Autor:
Brahm H. Segal, Emese Zsiros, Michael B. Yaffe, Kunle Odunsi, Kirsten B. Moysich, Kevin H. Eng, James A. Lederer, Sanjay Ram, Steven M. Holland, Jörg Eder, Holger Sellner, Anna Schubart, Viviana P. Ferreira, Lee-Ann H. Allen, Ilse Jongerius, Taco W. Kuijpers, Sora Suzuki, Mieke C. Brouwer, Cathelijn E.M. Aarts, Ivy L. Debreceni, Stephanie L. Silva-Del Toro, Kaitlyn Howard, Jason Ricciuti, ANM Nazmul H. Khan, Kelly L. Singel, Thejaswini Giridharan, Tiffany R. Emmons
Supplementary Figure S3: OC ascites fluid activates the classical and alternative pathways.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e9d0756f962f510cedda4ba0a9a0f6
https://doi.org/10.1158/2326-6066.22543210.v1
https://doi.org/10.1158/2326-6066.22543210.v1
Autor:
Brahm H. Segal, Emese Zsiros, Michael B. Yaffe, Kunle Odunsi, Kirsten B. Moysich, Kevin H. Eng, James A. Lederer, Sanjay Ram, Steven M. Holland, Jörg Eder, Holger Sellner, Anna Schubart, Viviana P. Ferreira, Lee-Ann H. Allen, Ilse Jongerius, Taco W. Kuijpers, Sora Suzuki, Mieke C. Brouwer, Cathelijn E.M. Aarts, Ivy L. Debreceni, Stephanie L. Silva-Del Toro, Kaitlyn Howard, Jason Ricciuti, ANM Nazmul H. Khan, Kelly L. Singel, Thejaswini Giridharan, Tiffany R. Emmons
T-cell activation and expansion in the tumor microenvironment (TME) are critical for antitumor immunity. Neutrophils in the TME acquire a complement-dependent T-cell suppressor phenotype that is characterized by inhibition of T-cell proliferation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d4f40cc451070fd401b4b199f38dd0
https://doi.org/10.1158/2326-6066.c.6550174
https://doi.org/10.1158/2326-6066.c.6550174
Autor:
Pascal Furet, Vincent Bordas, Mickaël Le Douget, Bahaa Salem, Yannick Mesrouze, Patricia Imbach‐Weese, Holger Sellner, Markus Voegtle, Nicolas Soldermann, Emilie Chapeau, Markus Wartmann, Clemens Scheufler, Cesar Fernandez, Joerg Kallen, Vito Guagnano, Patrick Chène, Tobias Schmelzle
Publikováno v:
ChemMedChem. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72eaa7a7b52b189acf9bc634916ec5d3
https://doi.org/10.1002/cmdc.202200514
https://doi.org/10.1002/cmdc.202200514
Autor:
Pascal Furet, Vincent Bordas, Mickaël Le Douget, Bahaa Salem, Yannick Mesrouze, Patricia Imbach‐Weese, Holger Sellner, Markus Voegtle, Nicolas Soldermann, Emilie Chapeau, Markus Wartmann, Clemens Scheufler, Cesar Fernandez, Joerg Kallen, Vito Guagnano, Patrick Chène, Tobias Schmelzle
Publikováno v:
ChemMedChem. 17(19)
Inhibition of the YAP-TEAD protein-protein interaction is an attractive therapeutic concept under intense investigation with the objective to treat cancers associated with a dysregulation of the Hippo pathway. However, owing to the very extended surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e849912e1b00046650c0d4b1f52f7eb
https://pubmed.ncbi.nlm.nih.gov/35950546
https://pubmed.ncbi.nlm.nih.gov/35950546
Autor:
Viviana P. Ferreira, Ilse Jongerius, Kelly L. Singel, Kunle Odunsi, Stephanie L. Silva-Del Toro, Thejaswini Giridharan, Anm Nazmul H. Khan, Jason Ricciuti, Kirsten B. Moysich, Kaitlyn Howard, Emese Zsiros, Kevin H. Eng, Tiffany R. Emmons, Brahm H. Segal, James A. Lederer, Sora Suzuki, Cathelijn E.M. Aarts, Holger Sellner, Taco W. Kuijpers, Mieke C. Brouwer, Steven M. Holland, Joerg Eder, Michael B. Yaffe, Ivy L. Debreceni, Anna Schubart, Sanjay Ram, Lee-Ann H. Allen
Publikováno v:
Cancer immunology research, 9(7), 790-810. American Association for Cancer Research Inc.
T-cell activation and expansion in the tumor microenvironment (TME) are critical for antitumor immunity. Neutrophils in the TME acquire a complement-dependent T-cell suppressor phenotype that is characterized by inhibition of T-cell proliferation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec2b3e407c4193b0f84c9e678f3bd26
http://www.scopus.com/inward/record.url?scp=85109040656&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85109040656&partnerID=8YFLogxK
Autor:
Nello Mainolfi, Takeru Ehara, Rajeshri G. Karki, Karen Anderson, Aengus Mac Sweeney, Sha-Mei Liao, Upendra A. Argikar, Keith Jendza, Chun Zhang, James Powers, Daniel W. Klosowski, Maura Crowley, Toshio Kawanami, Jian Ding, Myriam April, Cornelia Forster, Michael Serrano-Wu, Michael Capparelli, Rrezarta Ramqaj, Catherine Solovay, Frederic Cumin, Thomas M. Smith, Luciana Ferrara, Wendy Lee, Debby Long, Melissa Prentiss, Andrea De Erkenez, Louis Yang, Fang Liu, Holger Sellner, Finton Sirockin, Eric Valeur, Paulus Erbel, Daniela Ostermeier, Paul Ramage, Bernd Gerhartz, Anna Schubart, Stefanie Flohr, Nathalie Gradoux, Roland Feifel, Barbara Vogg, Christian Wiesmann, Jürgen Maibaum, Jörg Eder, Richard Sedrani, Richard A. Harrison, Muneto Mogi, Bruce D. Jaffee, Christopher M. Adams
Publikováno v:
Journal of Medicinal Chemistry. 63:5697-5722
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::161530bd60ced781537b4b5cf97869fc
https://doi.org/10.1021/acs.jmedchem.9b01870
https://doi.org/10.1021/acs.jmedchem.9b01870
Autor:
Tobias Schmelzle, Emilie Chapeau, Daniel Bauer, Patrick Chene, Jason Faris, Cesar Fernandez, Pascal Furet, Giorgio Galli, Jiachang Gong, Stephanie Harlfinger, Francesco Hofmann, Eloisa Jimenez Nunez, Joerg Kallen, Thanos Mourikis, Laurent Sansregret, Paulo Santos, Clemens Scheufler, Holger Sellner, Markus Voegtle, Markus Wartmann, Peter Wessels, Frederic Zecri, Nicolas Soldermann
Publikováno v:
Cancer Research. 83:LB319-LB319
The YAP-TEAD protein-protein interaction (PPI) is a critical event known to mediate YAP oncogenic functions downstream of the Hippo pathway. Current advanced pharmacological agents which aim at inhibiting YAP-TEAD oncogenic function do so by engaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad77e2db1f0369ac9729c839360bd713
https://doi.org/10.1158/1538-7445.am2023-lb319
https://doi.org/10.1158/1538-7445.am2023-lb319