Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Holger, Taschenberger"'
Autor:
Tommaso Zeppillo, Heba Ali, Sowbarnika Ravichandran, Tamara C. Ritter, Sally Wenger, Francisco J. López-Murcia, Erinn Gideons, Janetti Signorelli, Michael J. Schmeisser, Jens Wiltfang, JeongSeop Rhee, Nils Brose, Holger Taschenberger, Dilja Krueger-Burg
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Neuroligin-2 (Nlgn2) is a key synaptic adhesion protein at virtually all GABAergic synapses, which recruits GABAARs by promoting assembly of the postsynaptic gephyrin scaffold. Intriguingly, loss of Nlgn2 differentially affects subsets of GA
Externí odkaz:
https://doaj.org/article/41e5aaf4d91e4e0cb3c838533f2777d1
Autor:
Manvendra Singh, Ying Zhao, Vinicius Daguano Gastaldi, Sonja M. Wojcik, Yasmina Curto, Riki Kawaguchi, Ricardo M. Merino, Laura Fernandez Garcia-Agudo, Holger Taschenberger, Nils Brose, Daniel Geschwind, Klaus-Armin Nave, Hannelore Ehrenreich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Recombinant human erythropoietin (rhEPO) has potent procognitive effects, likely hematopoiesis-independent, but underlying mechanisms and physiological role of brain-expressed EPO remained obscure. Here, we provide transcriptional hippocampa
Externí odkaz:
https://doaj.org/article/96efba9a694c49e598c5b30a2073b0e7
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S331- (2023)
Externí odkaz:
https://doaj.org/article/925698e5a84f4ae28bdb6b292866f43e
Autor:
Christian Keine, Mohammed Al-Yaari, Tamara Radulovic, Connon I Thomas, Paula Valino Ramos, Debbie Guerrero-Given, Mrinalini Ranjan, Holger Taschenberger, Naomi Kamasawa, Samuel M Young Jr
Publikováno v:
eLife, Vol 11 (2022)
Synapses contain a limited number of synaptic vesicles (SVs) that are released in response to action potentials (APs). Therefore, sustaining synaptic transmission over a wide range of AP firing rates and timescales depends on SV release and replenish
Externí odkaz:
https://doaj.org/article/72cde114cf3040d9b27dec89dc94dd1c
Autor:
Olga Babaev, Hugo Cruces-Solis, Carolina Piletti Chatain, Matthieu Hammer, Sally Wenger, Heba Ali, Nikolaos Karalis, Livia de Hoz, Oliver M. Schlüter, Yuchio Yanagawa, Hannelore Ehrenreich, Holger Taschenberger, Nils Brose, Dilja Krueger-Burg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
IgSF9b is a synaptic adhesion protein that has been linked to psychiatric disorders. Here the authors show that deletion of IgSF9b regulates anxiety-like behaviour in mice by increasing inhibitory synaptic transmission in the centromedial amygdala.
Externí odkaz:
https://doaj.org/article/362f3b269d1245b2923fe26c721003ee
Publikováno v:
Cell Reports, Vol 26, Iss 10, Pp 2521-2530.e5 (2019)
Summary: SNARE-mediated synaptic vesicle (SV) fusion is controlled by multiple regulatory proteins that determine neurotransmitter release efficiency. Complexins are essential SNARE regulators whose mode of action is unclear, as available evidence in
Externí odkaz:
https://doaj.org/article/1f732c93a36c40b89b28f4499e131a18
Autor:
Iron Weichard, Holger Taschenberger, Felix Gsell, Grit Bornschein, Andreas Ritzau-Jost, Hartmut Schmidt, Robert J. Kittel, Jens Eilers, Erwin Neher, Stefan Hallermann, Jana Nerlich
Pre- and postsynaptic forms of long-term potentiation (LTP) are candidate synaptic mechanisms underlying learning and memory. At layer 5 pyramidal neurons LTP increases the initial synaptic strength but also short-term depression during high-frequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7930d6f51f14370cc4c146801fc9c61c
https://doi.org/10.1101/2023.04.11.535831
https://doi.org/10.1101/2023.04.11.535831
Autor:
Manvendra Singh, Ying Zhao, Vinicius Daguano Gastaldi, Sonja M. Wojcik, Yasmina Curto, Riki Kawaguchi, Ricardo M. Merino, Laura Fernandez Garcia-Agudo, Holger Taschenberger, Nils Brose, Daniel Geschwind, Klaus-Armin Nave, Hannelore Ehrenreich
Recombinant human erythropoietin (rhEPO) has potent procognitive effects, hematopoiesis-independent, but underlying mechanisms and physiological role of brain-expressed EPO have remained obscure. Here, we provide encyclopedic transcriptional hippocam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d6f7a7ee8dd4bdf860dfdd49d5fa0de
https://doi.org/10.1101/2023.02.04.527116
https://doi.org/10.1101/2023.02.04.527116
Autor:
Konrad Platzer, Heinrich Sticht, Caleb Bupp, Mythily Ganapathi, Elaine M. Pereira, Gwenaël Le Guyader, Frederic Bilan, Lindsay B. Henderson, Johannes R. Lemke, Holger Taschenberger, Nils Brose, Rami Abou Jamra, Sonja M. Wojcik
Publikováno v:
Annals of Neurology
Objective: Rare inherited missense variants in SLC32A1, the gene that encodes the vesicular gamma-aminobutyric acid (GABA) transporter, have recently been shown to cause genetic epilepsy with febrile seizures plus. We aimed to clarify if de novo miss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10995b1b9c9da07811cc2b5de15ad672
https://hdl.handle.net/21.11116/0000-000C-9FCD-B21.11116/0000-000B-40CD-6
https://hdl.handle.net/21.11116/0000-000C-9FCD-B21.11116/0000-000B-40CD-6
Autor:
Matthieu Hammer, Dilja Krueger-Burg, Liam Patrick Tuffy, Benjamin Hillman Cooper, Holger Taschenberger, Sarit Pati Goswami, Hannelore Ehrenreich, Peter Jonas, Frederique Varoqueaux, Jeong-Seop Rhee, Nils Brose
Publikováno v:
Cell Reports, Vol 13, Iss 3, Pp 516-523 (2015)
Loss-of-function mutations in the synaptic adhesion protein Neuroligin-4 are among the most common genetic abnormalities associated with autism spectrum disorders, but little is known about the function of Neuroligin-4 and the consequences of its los
Externí odkaz:
https://doaj.org/article/667388ddc3cc4c2a98b9a39a1297d127