Zobrazeno 1 - 10
of 271 567
pro vyhledávání: '"Holger"'
Autor:
Justus S. Israel, Laura-Maria Marcelin, Sherif Mehralivand, Jana Scholze, Jörg Hofmann, Matthias B. Stope, Martin Puhr, Christian Thomas, Holger H. H. Erb
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract Introduction Dysregulated androgen receptor (AR) activity is central to various diseases, particularly prostate cancer (PCa), in which it drives tumour initiation and progression. Consequently, antagonising AR activity via anti-androgens is
Externí odkaz:
https://doaj.org/article/7393c3fec1f5417aa2839dba9436cbb5
Autor:
George Martvel, Teddy Lazebnik, Marcelo Feighelstein, Lea Henze, Sebastian Meller, Ilan Shimshoni, Friederike Twele, Alexandra Schütter, Nora Foraita, Sabine Kästner, Lauren Finka, Stelio P. L. Luna, Daniel S. Mills, Holger A. Volk, Anna Zamansky
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Affective states are reflected in the facial expressions of all mammals. Facial behaviors linked to pain have attracted most of the attention so far in non-human animals, leading to the development of numerous instruments for evaluating pain
Externí odkaz:
https://doaj.org/article/28a19f6ee2714e309df9cbb1078118b7
Autor:
Veronika Golubinskaya, Holger Nilsson, Halfdan Rydbeck, William Hellström, Gunnel Hellgren, Ann Hellström, Karin Sävman, Carina Mallard
Publikováno v:
BMC Pediatrics, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Cytokines and growth factors (GF) have been implicated in the development of retinopathy of prematurity (ROP) and bronchopulmonary dysplasia (BPD). We hypothesize that even small coordinated changes in inflammatory proteins or GFs
Externí odkaz:
https://doaj.org/article/16a2225650aa4fb2861fd6660705ccbe
Autor:
Hafiza Noor Ul Ayan, Yvonne Nitschke, Abdul Razzaq Mughal, Holger Thiele, Naveed Altaf Malik, Ijaz Hussain, Syed Muhammad Ijlal Haider, Frank Rutsch, Jeanette Erdmann, Muhammad Tariq, Zouhair Aherrahrou, Ilyas Ahmad
Publikováno v:
BMC Pediatrics, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) plays a critical role by converting extracellular ATP to AMP, generating extracellular PPi, a potential inhibitor of calcification. Pathogenic variants in the ENPP1 cause generalized
Externí odkaz:
https://doaj.org/article/99f8a7384195499cb0725455db5cf3c2
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Aim was to compare image-guided navigation with a robot-assisted solution for performing MISS regarding precision, required time and subjective aspects. 90 pedicles were instrumented on two torsos, half with navigation, half robot-assisted.
Externí odkaz:
https://doaj.org/article/2520fe492b5c4573a83323904eb6cd95
Autor:
Rebekka Wegmann, Ximena Bonilla, Ruben Casanova, Stéphane Chevrier, Ricardo Coelho, Cinzia Esposito, Joanna Ficek-Pascual, Sandra Goetze, Gabriele Gut, Francis Jacob, Andrea Jacobs, Jack Kuipers, Ulrike Lischetti, Julien Mena, Emanuela S. Milani, Michael Prummer, Jacobo Sarabia Del Castillo, Franziska Singer, Sujana Sivapatham, Nora C. Toussaint, Oliver Vilinovszki, Mattheus H. E. Wildschut, Tharshika Thavayogarajah, Disha Malani, The TumorProfiler Consortium, Rudolf Aebersold, Marina Bacac, Niko Beerenwinkel, Christian Beisel, Bernd Bodenmiller, Viola Heinzelmann-Schwarz, Viktor H. Koelzer, Mitchell P. Levesque, Holger Moch, Lucas Pelkmans, Gunnar Rätsch, Markus Tolnay, Andreas Wicki, Bernd Wollscheid, Markus G. Manz, Berend Snijder, Alexandre P. A. Theocharides
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Deep single-cell multi-omic profiling offers a promising approach to understand and overcome drug resistance in relapsed or refractory (rr) acute myeloid leukemia (AML). Here, we combine single-cell ex vivo drug profiling (pharmacoscopy) wit
Externí odkaz:
https://doaj.org/article/d909919fc46044dd87b6ffb2a1e8a194
Autor:
Tobias Guenther, Anna Coulibaly, Sonia Y. Velásquez, Jutta Schulte, Tanja Fuderer, Timo Sturm, Bianka Hahn, Manfred Thiel, Holger A. Lindner
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Trauma and infection induce emergency granulopoiesis. Counts of immature granulocytes and transcriptional pathways of terminal granulocytic differentiation in blood are elevated in sepsis but correlate with disease severity. This
Externí odkaz:
https://doaj.org/article/71fc5b2275444429bc87c224e2078e1d
Autor:
Stephan Gerling, Robert Dalla-Pozza, Holger Michel, André Jakob, Michael Melter, Markus Johannes Dechant
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Kawasaki Disease (KD) is a multisystemic vasculitis of medium- and small-sized arteries. Abnormal intimal thickening may develop in the involved arterial area after regression of coronary artery aneurysm (CAA). Intimal dysfunction may induce
Externí odkaz:
https://doaj.org/article/aef7f82c2e874a7f82c8b697f5890f6c
Autor:
Annemarie Klatt, Jannis O. Wollschlaeger, Franziska B. Albrecht, Sara Rühle, Lena B. Holzwarth, Holger Hrenn, Tanja Melzer, Simon Heine, Petra J. Kluger
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Cultured or cultivated meat, animal muscle, and fat tissue grown in vitro, could transform the global meat market, reducing animal suffering while using fewer resources than traditional meat production and no antimicrobials at all. To ensure
Externí odkaz:
https://doaj.org/article/4d0f92a363aa406695dd8f4a51ae1568
Autor:
Andreas Weimer, Florian Recker, Thomas Vieth, Holger Buggenhagen, Christian Schamberger, Rainer Berthold, Svenja Berthold, Stephan Stein, Gerhard Schmidmaier, Roman Kloeckner, Ricarda Neubauer, Lukas Müller, Julia Weinmann-Menke, Johannes Weimer
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Introduction Musculoskeletal ultrasound (MSUS) is integral to routine clinical diagnostics for musculoskeletal and joint disorders. This study aims to establish and validate a sonography course tailored to undergraduate medical students acqu
Externí odkaz:
https://doaj.org/article/a13cd08de6b74cdcb6043c9d070d6c40