Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Holden C. Stefan"'
Autor:
Nicole L. Arruda, Zachary M. Carico, Megan Justice, Ying Frances Liu, Junjie Zhou, Holden C. Stefan, Jill M. Dowen
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-17 (2020)
Abstract Background The three-dimensional organization of the genome in the nucleus plays an integral role in many biological processes, including gene expression. The genome is folded into DNA loops that bring together distal regulatory elements and
Externí odkaz:
https://doaj.org/article/aec3e4ceb64740acba5b0e7b18750172
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009435 (2021)
The cohesin complex spatially organizes interphase chromatin by bringing distal genomic loci into close physical proximity, looping out the intervening DNA. Mutation of cohesin complex subunits is observed in cancer and developmental disorders, but t
Externí odkaz:
https://doaj.org/article/74bd8bc1527a43c6862d1be5e8260b8a
Autor:
Holden C. Stefan, Junjie Zhou, Nicole L Arruda, Ying Frances Liu, Jill M. Dowen, Zachary M. Carico, Megan Justice
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-17 (2020)
Epigenetics & Chromatin
Epigenetics & Chromatin
Background The three-dimensional organization of the genome in the nucleus plays an integral role in many biological processes, including gene expression. The genome is folded into DNA loops that bring together distal regulatory elements and genes. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1c611805b2d06f7b3fdb0aff9d82a4
http://link.springer.com/article/10.1186/s13072-020-00353-9
http://link.springer.com/article/10.1186/s13072-020-00353-9
Autor:
Junjie Zhou, Natalie L Rittenhouse, Zachary M. Carico, Ying Frances Liu, Jill M. Dowen, Nicole L Arruda, Holden C. Stefan
Publikováno v:
Genetics
Cohesin is a ring-shaped protein complex that controls dynamic chromosome structure. Cohesin activity is important for a variety of biological processes, including formation of DNA loops that regulate gene expression. The precise mechanisms by which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0111e042ce2d3ac53c01947a3fd0728
https://pubmed.ncbi.nlm.nih.gov/33704438
https://pubmed.ncbi.nlm.nih.gov/33704438
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009435 (2021)
PLoS Genetics
PLoS Genetics
The cohesin complex spatially organizes interphase chromatin by bringing distal genomic loci into close physical proximity, looping out the intervening DNA. Mutation of cohesin complex subunits is observed in cancer and developmental disorders, but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee630ea8dbd73056291f3fa7c14214f
https://doi.org/10.1371/journal.pgen.1009435
https://doi.org/10.1371/journal.pgen.1009435
Publikováno v:
Cell reports
SUMMARY Chromosome structure is a key regulator of gene expression. CTCF and cohesin play critical roles in structuring chromosomes by mediating physical interactions between distant genomic sites. The resulting DNA loops often contain genes and thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf385475e7b4e8de6374a276bf89d170
https://doi.org/10.1016/j.celrep.2020.03.067
https://doi.org/10.1016/j.celrep.2020.03.067