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Akademický článek

Sex-Dependent Effects on Influenza-Specific Antibody Quantity and Neutralizing Activity following Vaccination of Newborn Non-Human Primates Is Determined by Adjuvants.

Autor: Holbrook BC; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Rm 2E-018 Biotech Place, 575 North Patterson Ave., Winston-Salem, NC 27101, USA., Clemens EA; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Rm 2E-018 Biotech Place, 575 North Patterson Ave., Winston-Salem, NC 27101, USA., Alexander-Miller MA; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Rm 2E-018 Biotech Place, 575 North Patterson Ave., Winston-Salem, NC 27101, USA.

Publikováno v: Vaccines [Vaccines (Basel)] 2024 Apr 15; Vol. 12 (4). Date of Electronic Publication: 2024 Apr 15.

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Akademický článek

An Analysis of Linker-Dependent Effects on the APC Activation and In Vivo Immunogenicity of an R848-Conjugated Influenza Vaccine.

Autor: Crofts KF; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Page CL; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Swedik SM; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Holbrook BC; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Meyers AK; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Zhu X; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA.; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Parsonage D; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Westcott MM; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Alexander-Miller MA; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA.

Publikováno v: Vaccines [Vaccines (Basel)] 2023 Jul 20; Vol. 11 (7). Date of Electronic Publication: 2023 Jul 20.

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Akademický článek

Maternal influenza vaccination preferentially boosts hemagglutinin stem-specific antibody resulting in efficient transplacental transfer of stem-specific IgG.

Autor: Zuber MJ; Department of Obstetrics and Gynecology, Section of Maternal-Fetal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA., Stamilio DM; Department of Obstetrics and Gynecology, Section of Maternal-Fetal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA., Holbrook BC; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA., Snively BM; Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA., Jensen ET; Department of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA., Alexander-Miller MA; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

Publikováno v: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics [Int J Gynaecol Obstet] 2023 Jul; Vol. 162 (1), pp. 163-168. Date of Electronic Publication: 2023 Feb 10.

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Akademický článek

Frailty impacts immune responses to Moderna COVID-19 mRNA vaccine in older adults.

Autor: Semelka CT; Section on Geriatric Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USA. csemelka@wakehealth.edu., DeWitt ME; Section on Infectious Diseases, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USA., Blevins MW; Section on Infectious Diseases, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USA., Holbrook BC; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston Salem, NC, USA., Sanders JW; Section on Infectious Diseases, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USA., Alexander-Miller MA; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston Salem, NC, USA.

Publikováno v: Immunity & ageing : I & A [Immun Ageing] 2023 Jan 17; Vol. 20 (1), pp. 4. Date of Electronic Publication: 2023 Jan 17.

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Akademický článek

TLR agonists induce sustained IgG to hemagglutinin stem and modulate T cells following newborn vaccination.

Autor: Clemens EA; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, USA., Holbrook BC; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, USA., McNeilly B; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, USA., Kanekiyo M; Vaccine Research Center, NIAID, NIH, Bethesda, USA., Graham BS; Vaccine Research Center, NIAID, NIH, Bethesda, USA., Alexander-Miller MA; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, USA. Martha.Alexander-Miller@wakehealth.edu.

Publikováno v: NPJ vaccines [NPJ Vaccines] 2022 Aug 29; Vol. 7 (1), pp. 102. Date of Electronic Publication: 2022 Aug 29.

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Frailty and Age Impact Immune Responses to Moderna COVID-19 mRNA Vaccine.

Autor: Semelka CT; Wake Forest University School of Medicine., DeWitt ME; Wake Forest University School of Medicine., Blevins MW; Wake Forest University School of Medicine., Holbrook BC; Wake Forest University School of Medicine., Sanders JW; Wake Forest University School of Medicine., Alexander-Miller MA; Wake Forest University School of Medicine.

Publikováno v: Research square [Res Sq] 2022 Aug 01. Date of Electronic Publication: 2022 Aug 01.

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Akademický článek

Analysis of R848 as an Adjuvant to Improve Inactivated Influenza Vaccine Immunogenicity in Elderly Nonhuman Primates.

Autor: Crofts KF; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Holbrook BC; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., D'Agostino RB Jr; Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA., Alexander-Miller MA; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA.

Publikováno v: Vaccines [Vaccines (Basel)] 2022 Mar 23; Vol. 10 (4). Date of Electronic Publication: 2022 Mar 23.

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