Hepatoprotective and cardioprotective effects of empagliflozin in spontaneously hypertensive rats fed a high-fat diet.

Autor: Hojná S; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Malínská H; Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic., Hüttl M; Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic., Vaňourková Z; Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic., Marková I; Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic., Miklánková D; Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic., Hrdlička J; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Papoušek F; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Neckář J; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic; Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic., Kujal P; 3rd Faculty of Medicine, Charles University, Prague, Czech Republic., Behuliak M; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Rauchová H; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Kadlecová M; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Sedmera D; 1st Faculty of Medicine, Charles University, Prague, Czech Republic., Neffeová K; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic; 1st Faculty of Medicine, Charles University, Prague, Czech Republic., Zábrodská E; 1st Faculty of Medicine, Charles University, Prague, Czech Republic., Olejníčková V; 1st Faculty of Medicine, Charles University, Prague, Czech Republic., Zicha J; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Vaněčková I; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic. Electronic address: ivana.vaneckova@fgu.cas.cz.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 May; Vol. 174, pp. 116520. Date of Electronic Publication: 2024 Apr 05.

Obesity, Cardiovascular and Neurodegenerative Diseases: Potential Common Mechanisms.

Autor: Kuneš J; Institute of Physiology AS CR, Prague, Czech Republic. kunes@biomed.cas.cz. Research Institute of McGill University Health Centre (RI-MUHC), Québac, Canada, rhian.touyz@mcgill.ca., Hojná S, Mráziková L, Montezano A, Touyz RM, Maletínská L

Publikováno v: Physiological research [Physiol Res] 2023 Jul 31; Vol. 72 (Suppl 2), pp. S73-S90.

Both central sympathoexcitation and peripheral angiotensin II-dependent vasoconstriction contribute to hypertension development in immature heterozygous Ren-2 transgenic rats.

Autor: Řezáčová L; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Vaněčková I; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic. ivana.vaneckova@fgu.cas.cz., Hojná S; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Vavřínová A; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Valovič P; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Rauchová H; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Behuliak M; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic., Zicha J; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic.

Publikováno v: Hypertension research : official journal of the Japanese Society of Hypertension [Hypertens Res] 2022 Mar; Vol. 45 (3), pp. 414-423. Date of Electronic Publication: 2021 Oct 08.

Empagliflozin Is Not Renoprotective in Non-Diabetic Rat Models of Chronic Kidney Disease.

Autor: Hojná S; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic., Kotsaridou Z; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic.; Department of Biotechnology, Agricultural University, 11855 Athens, Greece., Vaňourková Z; Institute for Clinical and Experimental Medicine, 14220 Prague, Czech Republic., Rauchová H; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic., Behuliak M; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic., Kujal P; Department of Pathology, Third Faculty of Medicine, Charles University, 14220 Prague, Czech Republic., Kadlecová M; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic., Zicha J; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic., Vaněčková I; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic.

Publikováno v: Biomedicines [Biomedicines] 2022 Oct 07; Vol. 10 (10). Date of Electronic Publication: 2022 Oct 07.

Beneficial Effects of Empagliflozin Are Mediated by Reduced Renal Inflammation and Oxidative Stress in Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein.

Autor: Malínská H; Institute for Clinical and Experimental Medicine, 14220 Prague, Czech Republic., Hüttl M; Institute for Clinical and Experimental Medicine, 14220 Prague, Czech Republic., Marková I; Institute for Clinical and Experimental Medicine, 14220 Prague, Czech Republic., Miklánková D; Institute for Clinical and Experimental Medicine, 14220 Prague, Czech Republic., Hojná S; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic., Papoušek F; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic., Šilhavý J; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic., Mlejnek P; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic., Zicha J; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic., Hrdlička J; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic., Pravenec M; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic., Vaněčková I; Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic.

Publikováno v: Biomedicines [Biomedicines] 2022 Aug 24; Vol. 10 (9). Date of Electronic Publication: 2022 Aug 24.