Supramolecular assembly of protein building blocks: from folding to function

Autor: Nam Hyeong Kim, Hojae Choi, Zafar Muhammad Shahzad, Heesoo Ki, Jaekyoung Lee, Heeyeop Chae, Yong Ho Kim

Publikováno v: Nano Convergence, Vol 9, Iss 1, Pp 1-17 (2022)

Abstract Several phenomena occurring throughout the life of living things start and end with proteins. Various proteins form one complex structure to control detailed reactions. In contrast, one protein forms various structures and implements other b

Externí odkaz: https://doaj.org/article/7fd0ffa69a334cecb95e180714ec496d

Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.

Autor: Rosaysela Santos, Shimako Kawauchi, Russell E Jacobs, Martha E Lopez-Burks, Hojae Choi, Jamie Wikenheiser, Benedikt Hallgrimsson, Heather A Jamniczky, Scott E Fraser, Arthur D Lander, Anne L Calof

Publikováno v: PLoS Biology, Vol 14, Iss 9, p e2000197 (2016)

Elucidating the causes of congenital heart defects is made difficult by the complex morphogenesis of the mammalian heart, which takes place early in development, involves contributions from multiple germ layers, and is controlled by many genes. Here,

Externí odkaz: https://doaj.org/article/a35153e1e5d649febbe5a6a1db5ddb10

Necessity of individual and community-level efforts to prevent violent extremism

Autor: HoJae Choi, ChangYun Jung

Publikováno v: The korean Association of Police Science Review. 22:81-104

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b3dc71ca2d1b4d2608385c6a3843f14
https://doi.org/10.24055/kaps.22.4.4

Drug repositioning for enzyme modulator based on human metabolite-likeness

Autor: Gwan-Su Yi, Boah Lee, Yoon Hyeok Lee, Hojae Choi, Seongyong Park

Publikováno v: BMC Bioinformatics, Vol 18, Iss S7, Pp 15-24 (2017)
BMC Bioinformatics

Background Recently, the metabolite-likeness of the drug space has emerged and has opened a new possibility for exploring human metabolite-like candidates in drug discovery. However, the applicability of metabolite-likeness in drug discovery has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa8f33e60f310dfd56e7e6d5098c3c1
http://link.springer.com/article/10.1186/s12859-017-1637-5

Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects

Autor: Hojae Choi, Scott E. Fraser, Russell E. Jacobs, Arthur D. Lander, Heather A. Jamniczky, Anne L. Calof, Benedikt Hallgrímsson, Jamie Wikenheiser, Shimako Kawauchi, Martha E. Lopez-Burks, Rosaysela Santos

Publikováno v: PLoS Biology, Vol 14, Iss 9, p e2000197 (2016)
PLoS biology, vol 14, iss 9
Santos, R; Kawauchi, S; Jacobs, RE; Lopez-Burks, ME; Choi, H; Wikenheiser, J; et al.(2016). Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects.. PLoS Biol, 14(9), e2000197. doi: 10.1371/journal.pbio.2000197. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/50w416g5

Elucidating the causes of congenital heart defects is made difficult by the complex morphogenesis of the mammalian heart, which takes place early in development, involves contributions from multiple germ layers, and is controlled by many genes. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070224ce72659ad31bfd1e2062ceebea
http://europepmc.org/articles/PMC5016002?pdf=render