Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Hojabr, Kakavand"'
Autor:
Helen Rizos, Richard A. Scolyer, Georgina V. Long, James S. Wilmott, John F. Thompson, Robyn P.M. Saw, Julie R. Howle, Richard F. Kefford, Matteo S. Carlino, Alexander M. Menzies, Jean Y. H. Yang, Gulietta M. Pupo, Robert V. Rawson, Hojabr Kakavand
Purpose: To examine the relationship between immune activity, PD-L1 expression, and tumor cell signaling, in metastatic melanomas prior to and during treatment with targeted MAPK inhibitors.Experimental Design: Thirty-eight tumors from 17 patients tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151a99a2857d24c50054047b0565154e
https://doi.org/10.1158/1078-0432.c.6525018
https://doi.org/10.1158/1078-0432.c.6525018
Autor:
Grant A. McArthur, Alexander Dobrovic, John W. Kelly, Rory Wolfe, Jonathan S. Cebon, Andreas Behren, John F. Thompson, Graham J. Mann, Hojabr Kakavand, Richard W. Tothill, Anthony T. Papenfuss, Catriona McLean, Richard A. Scolyer, Jason Li, Stephen Q. Wong, Victoria J. Mar
Supplementary Figure 1 - PDF file 91K, Schematic diagram of experimental procedure and bioinformatic analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45672e4045ea79093967f6572014b9c4
https://doi.org/10.1158/1078-0432.22448606.v1
https://doi.org/10.1158/1078-0432.22448606.v1
Autor:
Helen Rizos, Richard A. Scolyer, Georgina V. Long, James S. Wilmott, John F. Thompson, Robyn P.M. Saw, Julie R. Howle, Richard F. Kefford, Matteo S. Carlino, Alexander M. Menzies, Jean Y. H. Yang, Gulietta M. Pupo, Robert V. Rawson, Hojabr Kakavand
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8faccd77ab843bfeab828e04e9cb8bd0
https://doi.org/10.1158/1078-0432.22462152
https://doi.org/10.1158/1078-0432.22462152
Autor:
Richard A. Scolyer, Georgina V. Long, Richard F. Kefford, Matteo S. Carlino, John F. Thompson, Serigne Lo, Valerie Jakrot, Robyn P.M. Saw, Julie R. Howle, Adam J. Cooper, Benjamin Y. Kong, Elizabeth Liniker, Alexander Guminski, Jason Madore, Hojabr Kakavand, James S. Wilmott, Alexander M. Menzies, Ricardo E. Vilain
Gain in immune cell counts and Kaplan-Meier progression free survival curves.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdc91ab7ba907841dd1a031c458b199
https://doi.org/10.1158/1078-0432.22466861.v1
https://doi.org/10.1158/1078-0432.22466861.v1
Autor:
Grant A. McArthur, Alexander Dobrovic, John W. Kelly, Rory Wolfe, Jonathan S. Cebon, Andreas Behren, John F. Thompson, Graham J. Mann, Hojabr Kakavand, Richard W. Tothill, Anthony T. Papenfuss, Catriona McLean, Richard A. Scolyer, Jason Li, Stephen Q. Wong, Victoria J. Mar
Supplementary tables 1, 3 and 4 - XLSX file 31K, 1. Performance summary of exome sequencing and capture kit used for each sample 3. List of genes for each melanoma subtype 4. List of potential actionable mutations in BRAF/NRAS wild-type tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cfe680a42a788988e1a479450680c1
https://doi.org/10.1158/1078-0432.22448597
https://doi.org/10.1158/1078-0432.22448597
Autor:
Helen Rizos, Richard A. Scolyer, Georgina V. Long, James S. Wilmott, John F. Thompson, Robyn P.M. Saw, Julie R. Howle, Richard F. Kefford, Matteo S. Carlino, Alexander M. Menzies, Jean Y. H. Yang, Gulietta M. Pupo, Robert V. Rawson, Hojabr Kakavand
Genes Differentially expressed (q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::599a177db79a030c53d26e239a758797
https://doi.org/10.1158/1078-0432.22462149.v1
https://doi.org/10.1158/1078-0432.22462149.v1
Autor:
Grant A. McArthur, Alexander Dobrovic, John W. Kelly, Rory Wolfe, Jonathan S. Cebon, Andreas Behren, John F. Thompson, Graham J. Mann, Hojabr Kakavand, Richard W. Tothill, Anthony T. Papenfuss, Catriona McLean, Richard A. Scolyer, Jason Li, Stephen Q. Wong, Victoria J. Mar
Supplementary Table 2 - PDF file 16632K, Single nucleotide variants identified for each sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14cec28e545571e3d771ff1976b7d168
https://doi.org/10.1158/1078-0432.22448600.v1
https://doi.org/10.1158/1078-0432.22448600.v1
Autor:
Richard A. Scolyer, Georgina V. Long, Peter Hersey, Richard F. Kefford, John F. Thompson, Jennifer H. Yearley, Lauren E. Haydu, Ricardo Vilain, Alexander M. Menzies, James S. Wilmott, Hojabr Kakavand
Supplementary Figure 4. Decision tree used to categorize the pattern of PD-L1 positive staining based on the immune cell infiltrate, percentage of tumor cells expressing PD-L1 and the location of staining within the samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af6b86e443eb6573dd1998876fb881a
https://doi.org/10.1158/1078-0432.22458539
https://doi.org/10.1158/1078-0432.22458539
Autor:
Richard A. Scolyer, Georgina V. Long, Peter Hersey, Richard F. Kefford, John F. Thompson, Jennifer H. Yearley, Lauren E. Haydu, Ricardo Vilain, Alexander M. Menzies, James S. Wilmott, Hojabr Kakavand
Supplementary Figure 1. Heat map of patients grouped based on baseline (PRE) PD-L1, change in (Δ) PD-L1 expression, Δ tumor infiltrating lymphocytes (TILs) and Δ PD-1+ lymphocytes from PRE to early during treatment (EDT).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c813a3c841709e65cc9b80699cbaf6b
https://doi.org/10.1158/1078-0432.22458548.v1
https://doi.org/10.1158/1078-0432.22458548.v1
Autor:
Richard A. Scolyer, Georgina V. Long, Peter Hersey, Richard F. Kefford, John F. Thompson, Jennifer H. Yearley, Lauren E. Haydu, Ricardo Vilain, Alexander M. Menzies, James S. Wilmott, Hojabr Kakavand
Supplementary Table 2. The percentage of PD-L1 expressing tumor/immune cells and the intensity of staining in these samples used to derive the immuno-reactive score (IRS) for the 40 patients. *Immune cells= lymphocytes and macrophages.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8c57c186e2cd1b86060be953af8129
https://doi.org/10.1158/1078-0432.22458533
https://doi.org/10.1158/1078-0432.22458533