Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Hoi-Shan Wong"'
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101722- (2020)
Understanding how mitochondria contribute to cellular oxidative stress and drive signaling and disease is critical, but quantitative assessment is difficult. Our previous studies of cultured C2C12 cells used inhibitors of specific sites of superoxide
Externí odkaz:
https://doaj.org/article/e122d090ff5e494eb241de1cce182679
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Reactive oxygen species are important signaling molecules crucial for muscle differentiation and adaptation to exercise. However, their uncontrolled generation is associated with an array of pathological conditions. To identify and quantify the sourc
Externí odkaz:
https://doaj.org/article/f447c6fecc6e4b3a962720926571763c
Publikováno v:
Molecules, Vol 19, Iss 11, Pp 17649-17662 (2014)
Previous findings have demonstrated that β-sitosterol (BSS), an active component of Cistanches Herba, protected against oxidant injury in H9c2 cardiomyocytes and in rat hearts by enhancing mitochondrial glutathione redox cycling, possibly through th
Externí odkaz:
https://doaj.org/article/f5dd64bc082645beb99e620e5c77661f
Autor:
Mark A. Watson, Harmanmeet Brar, Edwin T. Gibbs, Hoi-Shan Wong, Pratiksha A. Dighe, Bryan McKibben, Stephan Riedmaier, Amy Siu, James S. Polakowski, Jason A. Segreti, Xiaoqin Liu, SeungWon Chung, Y. Marina Pliushchev, Nathan Gesmundo, Zhi Wang, Timothy A. Vortherms, Martin D. Brand
Publikováno v:
Free Radical Biology and Medicine. 204:276-286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42e21a0d962784d5ee051356fc0f9704
https://doi.org/10.1016/j.freeradbiomed.2023.05.022
https://doi.org/10.1016/j.freeradbiomed.2023.05.022
Autor:
Edwin T. Gibbs, Chad A. Lerner, Mark A. Watson, Hoi-Shan Wong, Akos A. Gerencser, Martin D. Brand
Publikováno v:
Biochemical Journal. 480:363-384
Superoxide/hydrogen peroxide production by site IQ in complex I of the electron transport chain is conventionally assayed during reverse electron transport (RET) from ubiquinol to NAD. However, S1QELs (specific suppressors of superoxide/hydrogen pero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993b68cd62480423fdf84cd63239aa14
https://doi.org/10.1042/bcj20220611
https://doi.org/10.1042/bcj20220611
Publikováno v:
Journal of Chemical Education. 98:3476-3485
The promotion of spatial skills is essential in chemistry education. However, the process of acquiring these skills can be monotonous if learning is limited to the memorization of Newman projections or 3D molecular kits. Existing approaches to learni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90b0c6502d8ee8d38937ea26c5807797
https://doi.org/10.1021/acs.jchemed.0c01029
https://doi.org/10.1021/acs.jchemed.0c01029
Autor:
Tim Esbenshade, Martin D. Brand, Ramzi F. Sweis, Simon Melov, Vojtech Mezera, Bryan McKibben, Pratiksha A. Dighe, Marina A. Pliushchev, Akos A. Gerencser, Zhi Wang, Stephan Riedmaier, Hoi Shan Wong
Publikováno v:
Free Radical Biology and Medicine. 164:223-232
Superoxide produced by mitochondria has been implicated in numerous physiologies and pathologies. Eleven different mitochondrial sites that can produce superoxide and/or hydrogen peroxide (O2.-/H2O2) have been identified in vitro, but little is known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c095b845147d44d9a789b4ecdc70dc50
https://doi.org/10.1016/j.freeradbiomed.2020.12.447
https://doi.org/10.1016/j.freeradbiomed.2020.12.447
Not just a cousin of the naked mole-rat: Damaraland mole-rats offer unique insights into biomedicine
Publikováno v:
Comp Biochem Physiol B Biochem Mol Biol
Evolutionary medicine has been a fast-growing field of biological research in the past decade. One of the strengths of evolutionary medicine is to use non-traditional model organisms which often exhibit unusual characteristics shaped by natural selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03223e0e3df03aaf80786c9d5e18564
https://pubmed.ncbi.nlm.nih.gov/35710053
https://pubmed.ncbi.nlm.nih.gov/35710053
Autor:
Hoi Shan Wong, Michael D. Roberts, Cristina Aurora Rodriguez-Wagner, Chidambaram Ramanathan, David A. Freeman, Rochelle Buffenstein, Kang Nian Yap, Yufeng Zhang
Publikováno v:
Biochim Biophys Acta Bioenerg
Naked mole-rats (NMR) and Damaraland mole-rats (DMR) are the only two eusocial mammals known. Both species exhibit extraordinary longevity for their body size, high tolerance to hypoxia and oxidative stress and high reproductive output; these collect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd8640579f459b2a31379718baad9fb
https://doi.org/10.1101/2021.08.05.455346
https://doi.org/10.1101/2021.08.05.455346
Publikováno v:
Free Radical Biology and Medicine. 143:545-559
Mitochondria are important sources of superoxide and hydrogen peroxide in cell signaling and disease. In particular, superoxide/hydrogen peroxide production during reverse electron transport from ubiquinol to NAD+ though Complex I is implicated in se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::508f78cb7f291ff52f0a04acdfb6ccce
https://doi.org/10.1016/j.freeradbiomed.2019.09.006
https://doi.org/10.1016/j.freeradbiomed.2019.09.006