Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Hoi Wing Leung"'
Autor:
Frank W. Pun, Bonnie Hei Man Liu, Xi Long, Hoi Wing Leung, Geoffrey Ho Duen Leung, Quinlan T. Mewborne, Junli Gao, Anastasia Shneyderman, Ivan V. Ozerov, Ju Wang, Feng Ren, Alexander Aliper, Evelyne Bischof, Evgeny Izumchenko, Xiaoming Guan, Ke Zhang, Bai Lu, Jeffrey D. Rothstein, Merit E. Cudkowicz, Alex Zhavoronkov
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease with ill-defined pathogenesis, calling for urgent developments of new therapeutic regimens. Herein, we applied PandaOmics, an AI-driven target discovery platform, to analyze th
Externí odkaz:
https://doaj.org/article/d12999749a99465fb2c046587d7bb7ef
Autor:
Nicole Pui Yu Ho, Carmen Oi Ning Leung, Tin Lok Wong, Eunice Yuen Ting Lau, Martina Mang Leng Lei, Etienne Ho Kit Mok, Hoi Wing Leung, Man Tong, Irene Oi Lin Ng, Jing Ping Yun, Stephanie Ma, Terence Kin Wah Lee
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-14 (2021)
Abstract Emerging evidence indicates the role of cancer stem cells (CSCs) in tumor relapse and therapeutic resistance in patients with hepatocellular carcinoma (HCC). To identify novel targets against liver CSCs, an integrative analysis of publicly a
Externí odkaz:
https://doaj.org/article/e24394bef0094c0fa49316ffef7fef79
Autor:
Andrea Olsen, Zachary Harpaz, Christopher Ren, Anastasia Shneyderman, Alexander Veviorskiy, Maria Dralkina, Simon Konnov, Olga Shcheglova, Frank W. Pun, Geoffrey Ho Duen Leung, Hoi Wing Leung, Ivan V. Ozerov, Alex Aliper, Mikhail Korzinkin, Alex Zhavoronkov
Publikováno v:
Aging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c9d8e29bc5cae572e6e34e139ade1d9
https://doi.org/10.18632/aging.204678
https://doi.org/10.18632/aging.204678
Autor:
Terence K. Lee, Stephanie Ma, Irene Oi Lin Ng, Qian Zhao, Cong Ma, Vincent W. Keng, Man Tong, Rainbow Wing Hei Leung, Martina Mang Leng Lei, Etienne H. Mok, Katherine Po Sin Chung, Eunice Y. Lau, Carmen Oi Ning Leung, Hoi Wing Leung
Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92657e47ff9407880df8a54a2e706e39
https://doi.org/10.1158/0008-5472.22428138
https://doi.org/10.1158/0008-5472.22428138
Autor:
Terence Kin Wah Lee, Stephanie Ma, David M. Baker, Jonathan D. Cybulski, Kit Sum Leung, Dan Lindholm, Chi Ho Lin, Hui Lian Zhu, Jun Yu, Jing Ping Yun, Jin Ding, Irene Oi Lin Ng, Eunice Yuen Ting Lau, Tin Lok Wong, Man Tong, Hoi Wing Leung, Martina Mang Leng Lei, Lei Zhou, Carmen Oi Ning Leung, Etienne Ho Kit Mok
Accumulating evidence has demonstrated that drug resistance can be acquired in cancer through the repopulation of tumors by cancer stem cell (CSC) expansion. Here, we investigated mechanisms driving resistance and CSC repopulation in hepatocellular c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdd019ff006c8a87c5a1887171d0fca7
https://doi.org/10.1158/0008-5472.c.6513947.v1
https://doi.org/10.1158/0008-5472.c.6513947.v1
Autor:
Terence K. Lee, Irene Oi-Lin Ng, Stephanie Ma, Regina Cheuk-Lam Lo, Chi Ho Lin, Lily K. Cheng, Shilpa Gurung, Nicole P. Ho, Carmen Oi-Ning Leung, Hoi-Wing Leung, Eunice Y. Lau, Bowie Y. Cheng
Oncomine analysis shows IRAK1 overexpression in cancers of breast, bladder, brain, colon, lung and ovary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ad65ef67c6e9923695a339bf309f14
https://doi.org/10.1158/0008-5472.22418030
https://doi.org/10.1158/0008-5472.22418030
Autor:
Terence K. Lee, Irene Oi-Lin Ng, Stephanie Ma, Regina Cheuk-Lam Lo, Chi Ho Lin, Lily K. Cheng, Shilpa Gurung, Nicole P. Ho, Carmen Oi-Ning Leung, Hoi-Wing Leung, Eunice Y. Lau, Bowie Y. Cheng
Suppl Materials, Figure Legends 1-7 and Tables showing clinico-pathological correlation of endogenous IRAK1, the effect of IRAK1 alternations on tumorigenicity as well as pathway analysis of HCC cells with or without IRAK1 suppressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98afc1d5d561c24c6b71344a168c80c9
https://doi.org/10.1158/0008-5472.22418015
https://doi.org/10.1158/0008-5472.22418015
Autor:
Terence K. Lee, Stephanie Ma, Irene Oi Lin Ng, Qian Zhao, Cong Ma, Vincent W. Keng, Man Tong, Rainbow Wing Hei Leung, Martina Mang Leng Lei, Etienne H. Mok, Katherine Po Sin Chung, Eunice Y. Lau, Carmen Oi Ning Leung, Hoi Wing Leung
The survival benefit derived from sorafenib treatment for patients with hepatocellular carcinoma (HCC) is modest due to acquired resistance. Targeting cancer stem cells (CSC) is a possible way to reverse drug resistance, however, inhibitors that spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1f61a41d4697753379474797e9f22d
https://doi.org/10.1158/0008-5472.c.6512922.v1
https://doi.org/10.1158/0008-5472.c.6512922.v1
Autor:
Terence Kin Wah Lee, Stephanie Ma, David M. Baker, Jonathan D. Cybulski, Kit Sum Leung, Dan Lindholm, Chi Ho Lin, Hui Lian Zhu, Jun Yu, Jing Ping Yun, Jin Ding, Irene Oi Lin Ng, Eunice Yuen Ting Lau, Tin Lok Wong, Man Tong, Hoi Wing Leung, Martina Mang Leng Lei, Lei Zhou, Carmen Oi Ning Leung, Etienne Ho Kit Mok
Supplementary Data from Caspase-3–Induced Activation of SREBP2 Drives Drug Resistance via Promotion of Cholesterol Biosynthesis in Hepatocellular Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f63ec71e7d707bff354f1cd70e435a
https://doi.org/10.1158/0008-5472.22431593.v1
https://doi.org/10.1158/0008-5472.22431593.v1
Autor:
Terence K. Lee, Irene Oi-Lin Ng, Stephanie Ma, Regina Cheuk-Lam Lo, Chi Ho Lin, Lily K. Cheng, Shilpa Gurung, Nicole P. Ho, Carmen Oi-Ning Leung, Hoi-Wing Leung, Eunice Y. Lau, Bowie Y. Cheng
Frequent relapse and drug resistance in patients with hepatocellular carcinoma (HCC) can be attributed to the existence of tumor-initiating cells (TIC) within the tumor bulk. Therefore, targeting liver TICs may improve the prognosis of these patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dbedac19678dd7e170ef711bfc93d3f
https://doi.org/10.1158/0008-5472.c.6510008.v1
https://doi.org/10.1158/0008-5472.c.6510008.v1