Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Hoi Tang, Ma"'
Autor:
Yue Yao, Yi Xu, Liang Yu, Ting‐Mao Xue, Zhi‐Jie Xiao, Pui‐Chi Tin, Hiu‐Ling Fung, Hoi‐Tang Ma, Jing‐Ping Yun, Judy Wai Ping Yam
Publikováno v:
Cancer Communications, Vol 44, Iss 2, Pp 251-272 (2024)
Abstract Background Small extracellular vesicles (sEVs) mediate intercellular communication that contributes to hepatocellular carcinoma (HCC) progression via multifaceted pathways. The success of cell entry determines the effect of sEV on recipient
Externí odkaz:
https://doaj.org/article/b2e9a3c31e724dc38e92fd0ac8e57e35
Publikováno v:
Life Science Alliance; Oct2024, Vol. 7 Issue 10, p1-16, 16p
Autor:
Hoi Tang Ma, Randy Y.C. Poon
Publikováno v:
Cell Reports, Vol 22, Iss 6, Pp 1439-1450 (2018)
Summary: The spindle assembly checkpoint (SAC) prevents premature segregation of chromosomes during mitosis. This process requires structural remodeling of MAD2 from O-MAD2 to C-MAD2 conformation. After the checkpoint is satisfied, C-MAD2 is reverted
Externí odkaz:
https://doaj.org/article/5cc400f92b42428c94b0d7754718bac8
Publikováno v:
Journal of Cell Science. 136
Switching genes on and off on cue is a cornerstone for understanding gene functions. One contemporary approach for loss-of-function studies of essential genes involves CRISPR-mediated knockout of the endogenous locus in conjunction with the expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3fb5d07d42892be0fa33d42ddbab0e4
https://doi.org/10.1242/jcs.260754
https://doi.org/10.1242/jcs.260754
Supplementary Video 7 from Determinants of Mitotic Catastrophe on Abrogation of the G2 DNA Damage Checkpoint by UCN-01
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2197fd6f2040d8c9a3425f075edfdcc9
https://doi.org/10.1158/1535-7163.22496929.v1
https://doi.org/10.1158/1535-7163.22496929.v1
Supplementary Video 5 from Determinants of Mitotic Catastrophe on Abrogation of the G2 DNA Damage Checkpoint by UCN-01
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f493a1912710dc5a4b72842ca8c1a05
https://doi.org/10.1158/1535-7163.22496935
https://doi.org/10.1158/1535-7163.22496935
Supplementary Video 8 from Determinants of Mitotic Catastrophe on Abrogation of the G2 DNA Damage Checkpoint by UCN-01
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc93e1b16aa6df6cf75988b77a6cfc8
https://doi.org/10.1158/1535-7163.22496926
https://doi.org/10.1158/1535-7163.22496926
Supplementary Video and Figure Legends from Determinants of Mitotic Catastrophe on Abrogation of the G2 DNA Damage Checkpoint by UCN-01
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c81d5686940e19ef0378c049d9bbcff
https://doi.org/10.1158/1535-7163.22496917.v1
https://doi.org/10.1158/1535-7163.22496917.v1
Genotoxic stress such as ionizing radiation halts entry into mitosis by activation of the G2 DNA damage checkpoint. The CHK1 inhibitor 7-hydroxystaurosporine (UCN-01) can bypass the checkpoint and induce unscheduled mitosis in irradiated cells. Preci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27e4d699df2cb7f18c04fc50a7e2812f
https://doi.org/10.1158/1535-7163.c.6535432
https://doi.org/10.1158/1535-7163.c.6535432
Supplementary Figures 1-8 from Determinants of Mitotic Catastrophe on Abrogation of the G2 DNA Damage Checkpoint by UCN-01
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fd5e4dfe9a716dc018b2f448815c9a
https://doi.org/10.1158/1535-7163.22496953.v1
https://doi.org/10.1158/1535-7163.22496953.v1