Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hoi M. Leung"'
Autor:
Darryl Toth, Tiffani K. Hamilton, David M. Pariser, Hoi M. Leung, Alan Menter, Graham Wetherill, Marvin Garovoy, Brian Hennessey, Paul Kwon
Publikováno v:
International Journal of Dermatology. 46:637-648
Background Rebound in psoriasis is, by definition, a rapid worsening of disease following the discontinuation of therapy for psoriasis; it occurs following the abrupt discontinuation of many therapies. To prevent rebound on discontinuation of efalizu
Publikováno v:
Journal of Cutaneous Medicine and Surgery. 11:57-66
Background: Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. Efalizumab, a T cell-targeted, recombinant human monoclonal antibody, is approved for the treatment of adult patients with chronic moderate to severe plaque
Autor:
Noel R. Mohberg, Robert L. Davis, Karl E. Peace, Anthony C. Segreti, Hoi M. Leung, Gary G. Koch
Publikováno v:
Journal of Biopharmaceutical Statistics. 11:347-372
The practice of statistics in the pharmaceutical industry has changed markedly over the last 25 years. This paper examines the evolution of clinical trial statistics in relationship to advances in statistical methodology and computational power as we
Autor:
Maria K. Hordinsky, Hoi M. Leung, Elyse S. Rafal, Ivor Caro, Basel Altrabulsi, Janet L. Roberts, Neil J. Korman, Elise A. Olsen, David A. Whiting, Vera H. Price, Elaine C. Siegfried, Marvin Garovoy
Publikováno v:
Journal of the American Academy of Dermatology. 58(3)
Background Alopecia areata (AA) is a T-cell–mediated autoimmune disease. Efalizumab is a T-cell–targeted therapy approved for the treatment of psoriasis. Objective To assess the efficacy and safety of efalizumab in the treatment of moderate-to-se
Autor:
Jerrold Weiss, Hoi M. Leung, Suganya Viriyakosol, Ofer Levy, Athmane Teghanemt, Eugenie E. Suter, Eva C. Guinan, Leighanne C. Gallington, Leslie A. Kalish, Robert J. Soiffer, Paul R. Walker, Janice Russell, Michael R. Wessels, Gregory P. Priebe, Patrick Scannon
Publikováno v:
Blood. 112:800-800
Background: HSCT is an important treatment modality complicated by a number of immune-mediated toxicities, including acute graft vs host disease (aGVHD). In animal HSCT models, endotoxemia-induced production of TNF contributes to development of infla
Autor:
Jerrold Weiss, Suganya Viriyakosol, Ofer Levy, Janice Russell, Eva C. Guinan, Robert J. Soiffer, Leighanne C. Gallington, Leslie A. Kalish, Patrick Scannon, Athmane Teghanemt, Eugenie E. Suter, Michael R. Wessels, Hoi M. Leung, Gregory P. Priebe
Publikováno v:
Blood. 110:1058-1058
Background: SCT is an important treatment modality complicated by a number of immune-mediated toxicities, including aGVHD. In animal SCT models, intestinal translocation of endotoxin (LPS) induces production of TNF-α contributing to development of a
Publikováno v:
Journal of Cutaneous Medicine & Surgery; Mar/Apr2007, Vol. 11 Issue 2, p57-66, 10p
Autor:
Lawrence L. Kupper, Hoi M. Leung
Publikováno v:
Communications in Statistics - Theory and Methods. 10:997-1015
Confidence interval estimation using the folded logarithmic (FL) transformation of maximum likelihood (ML) estimators is considered. The FL-based interval is found to have a smallerwidth and a larger confidence coefficient than the ML-based interval
Autor:
Hoi M. Leung, Stamatis Cambanis
Publikováno v:
Information and Control. 34:198-209
Consider a memoryless Gaussian vector source and assume that the variances of the components of its i.i.d. vectors are known and that no further information on their covariance structure is available. We study the dependence of the rate distortion fu
Autor:
Hoi M. Leung, Stamatis Cambanis
Publikováno v:
Information and Control. (2):116-133
We consider the evaluation of and bounds for the rate distortion functions of independent and identically distributed (i.i.d.) sources under a magnitude-error criterion. By refining the ingeneous approach of Tan and Yao we evaluate explicitly the rat