Plasma level of adrenomedullin is influenced by a single nucleotide polymorphism in the adiponectin gene.

Autor: Hoi Kin Wong, Kwok Leung Ong, Raymond Y H Leung, Tommy T Cheung, Aimin Xu, Tai Hing Lam, Karen S L Lam, Bernard M Y Cheung

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e70335 (2013)

ObjectiveAdrenomedullin (ADM) and adiponectin are both involved in inflammation and cardiovascular diseases. The plasma levels of these peptides are influenced by single nucleotide polymorphisms (SNPs) in the ADM and ADIPOQ genes respectively. There

Externí odkaz: https://doaj.org/article/50e51e8c88d843d48f0447d16463a17a

Low-pass genome sequencing versus chromosomal microarray analysis: implementation in prenatal diagnosis

Autor: Shaoyun Chen, Zhenjun Yang, Hoi Kin Wong, Kwong Wai Choy, Matthew Hoi Kin Chau, Zirui Dong, Yvonne K. Kwok, Kelin Xiao, Tak Yeung Leung, Cynthia C. Morton, Xiaofan Zhu, Rui Zhang, Zhuo Meng, Baoheng Gui, Kathy Yin Ching Tsang, Yanfang Wang, Sau Wai Cheung, Yuanfang Zhu, Huilin Wang

Publikováno v: Wang, H, Dong, Z, Zhang, R, Chau, M H K, Yang, Z, Tsang, K Y C, Wong, H K, Gui, B, Meng, Z, Xiao, K, Zhu, X, Wang, Y, Chen, S, Leung, T Y, Cheung, S W, Kwok, Y K, Morton, C C, Zhu, Y & Choy, K W 2019, ' Low-pass genome sequencing versus chromosomal microarray analysis: implementation in prenatal diagnosis ', Genetics in Medicine . https://doi.org/10.1038/s41436-019-0634-7
Genetics in medicine : official journal of the American College of Medical Genetics

PurposeEmerging studies suggest that low-pass genome sequencing (GS) provides additional diagnostic yield of clinically significant copy-number variants (CNVs) compared with chromosomal microarray analysis (CMA). However, a prospective back-to-back c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd719a939d29e76af5466674a07e75e
https://doi.org/10.1038/s41436-019-0634-7

Histological and microRNA Signatures of Corneal Epithelium in Keratoconus

Autor: Vishal Jhanji, Wai Kit Chu, Chi Pui Pang, Kwong Wai Choy, Tsz Kin Ng, Yu Meng Wang, Hoi Kin Wong

Publikováno v: Journal of Refractive Surgery. 34:201-211

PURPOSE: To illustrate the histopathology of keratoconic corneal epithelia and its micro-ribonucleic acid (miRNA) regulation. METHODS: Corneal epithelia were collected from 27 patients with keratoconus and 26 normal patients after surgery or by impre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566cca109f4a632aa015d678a49702cd
https://doi.org/10.3928/1081597x-20171215-02

The CCCTC-binding factor (CTCF)-forkhead box protein M1 axis regulates tumour growth and metastasis in hepatocellular carcinoma

Autor: Kenrick Kai Yuen Chan, Larry M.C. Chow, Alfred S. L. Cheng, Ka Fai To, Yue-Sun Cheung, Bin Zhang, Eunice Yuen-Ting Lau, Kwong Wai Choy, Ben C.B. Ko, Terence Kin Wah Lee, Anthony W.H. Chan, Nicole Pui Yu Ho, Yajing Zhang, Paul B.S. Lai, Hoi Kin Wong, Hang Liu, Xiaoping Zou, Rui Zhang, Vincent W. Keng

Publikováno v: The Journal of Pathology. 243:418-430

CCCTC-binding factor (CTCF) is a DNA-binding protein that interacts with a large number of highly divergent target sequences throughout the genome. It is implicated in a variety of functions, including chromatin organization and transcriptional contr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e301a73e0fb7eb273e2ac14e4feb7ed4
https://doi.org/10.1002/path.4976

Leadership, trust in management and acceptance of change in Hong Kong’s Civil Service Bureau

Autor: Mark Loon, Wen Juan Cai, Peter Hoi Kin Wong

Purpose The purpose of this paper is to examine whether trust in management mediates the relationships between two types of leadership (transactional and transformational) and acceptance of change in the Hong Kong public sector. Design/methodology/ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e401e06e6e0a9cea2e759d2dcc3bb9a5
https://hdl.handle.net/10453/134340