LB1005 Suppression of NRAS-mutant melanoma growth with NRAS-targeting ASO treatment reveals therapeutically relevant kinase co-dependencies

Autor: FEICHTENSCHLAGER, V., Zheng, Y.J., Qu, T., Hohlova, D., Callanan, C., Chen, L., Chen, C., Ho, W., Lee, A., Hwang, Y., Muñoz, D.P., Rappersberger, K., Coppe, J., Ortiz-Urda, S.

Publikováno v: In Journal of Investigative Dermatology August 2024 144(8) Supplement:S177-S177

The therapeutically actionable long non-coding RNA ' T-RECS ' is essential to cancer cells' survival in NRAS/MAPK-driven melanoma.

Autor: Feichtenschlager V; University of California San Francisco., Chen L; University of California San Francisco., Zheng YJ; University of California San Francisco., Ho W; University of California San Francisco., Sanlorenzo M; University of California San Francisco., Vujic I; Department of Dermatology and Venerology, Medical Institution Rudolfstiftung, Vienna, Austria., Fewings E; University of California San Francisco., Lee A; University of California San Francisco., Chen C; University of California San Francisco., Callanan C; University of California San Francisco., Lin K; University of California San Francisco., Qu T; University of California San Francisco., Hohlova D; University of California San Francisco., Vujic M; University of California San Francisco., Hwang Y; University of California, San Francisco., Lai K; University of California San Francisco., Chen S; University of California San Francisco., Nguyen T; University of California San Francisco., Muñoz DP; University of California at San Francisco., Kohwi Y; University of California at San Francisco., Posch C; Sigmund Freud Private University., Daud A; University of California at San Francisco., Rappersberger K; Department of Dermatology, Clinic Landstrasse Vienna, Academic Teaching Hospital, Medical University Vienna, Vienna, Austria., Kohwi-Shigematsu T; University of California at San Francisco., Coppé JP; University of California San Francisco., Ortiz-Urda S; University of California San Francisco.

Publikováno v: Research square [Res Sq] 2023 Dec 01. Date of Electronic Publication: 2023 Dec 01.