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Autor:
Obert, Arnd Jonathan, Gutberlet, Marcel, Kern, Agilo Luitger, Kaireit, Till Frederik, Glandorf, Julian, Moher Alsady, Tawfik, Wacker, Frank, Hohlfeld, Jens Michael, Vogel‐Claussen, Jens
Publikováno v:
Magnetic Resonance in Medicine; Aug2022, Vol. 88 Issue 2, p860-870, 11p
Autor:
Heratizadeh, Annice, Badorrek, Philipp, Niebuhr, Margarete, Erpenbeck, Veit Johannes, Lösche, C., Krug, Norbert, Hohlfeld, Jens Michael, Werfel, Thomas
It has frequently been speculated that pruritus and skin lesions develop after exposure to aeroallergens in sensitized patients with atopic dermatitis (AD). The aim of the present study was to assess the cutaneous reactions to grass pollen in adult p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______610::1743598f524f8020b13c8f1329b0fca7
https://publica.fraunhofer.de/handle/publica/236616
https://publica.fraunhofer.de/handle/publica/236616
Autor:
Holz, Olaf, Hansen, Tanja, Homburg, Ursula, Garn, Holger, Hohlfeld, Jens Michael, Niehof, Monika
Introduction: To enable gene expression analysis in sputum samples of patients with asthma following allergen provocation and treatment with a novel GATA-3 inhibitor (ClinicalTrials.gov Identifier: NCT0174376), we compared different RNA protection so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______610::95dfecd50e3da2e087ef8be78e9d9581
https://publica.fraunhofer.de/handle/publica/238523
https://publica.fraunhofer.de/handle/publica/238523
Autor:
Holz, Olaf, Gaida, Arne, Schuchardt, Sven, Langejuergen, Jens, Zimmermann, Stefan, Hohlfeld, Jens Michael
Introduction: A pronounced flow-dependence of a volatile breath component indicates an origin from central airways. There is data showing that ethanol concentrations (Bikov BMC Pulm Med 2013) and fragments of isoprene (Thekedar JBR 2010) in exhaled b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______610::80d87712786ebc63ec9acd740b213aab
https://publica.fraunhofer.de/handle/publica/238517
https://publica.fraunhofer.de/handle/publica/238517
Diamide does not improve the analysis of IL1b and TNFa in dithiothreitol-treated sputum supernatants
INTRODUCTION: There is one report (Milone et.al. ERS2012) that diamide can be used to re-oxidize disulfide bonds that were separated by DTT treatment during the homogenization of sputum samples, a process that can affect the analysis of mediators in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______610::a335bb27ab7f1074c5774f01872a088c
https://publica.fraunhofer.de/handle/publica/238085
https://publica.fraunhofer.de/handle/publica/238085
Autor:
Vogel-Claussen, Jens, Renne, Julius, Hinrichs, Jan, Schönfeld, Christian, Gutberlet, Marcel, Schaumann, Frank, Winkler, Carla, Faulenbach, Cornelia, Krug, Norbert, Wacker, Frank, Hohlfeld, Jens Michael
RATIONALE: There is a need to develop novel noninvasive imaging biomarkers that help to evaluate antiinflammatory asthma treatments. OBJECTIVES: To investigate whether the extent of the segmental lung edema measured noninvasively using turbo-inversio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______610::847b3eb77ec22067b5cd8365c744d814
https://publica.fraunhofer.de/handle/publica/237039
https://publica.fraunhofer.de/handle/publica/237039
Autor:
Holz, Olaf, Roepcke, Stefan, Lauer, Gereon, Elmlinger, Martin, Lahu, Gezim, Hohlfeld, Jens Michael
RATIONAL: COPD is often accompanied by a diminished exercise tolerance and reduced physical activity. To find novel COPD metabolome biomarkers we compared the serum of smokers with and without COPD after controlled food intake, before and after a per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______610::dee48ea08546a4e9e5ceac040ca1a618
https://publica.fraunhofer.de/handle/publica/238086
https://publica.fraunhofer.de/handle/publica/238086
Autor:
Holz, Olaf, Müller, Meike, Ignatenko, Stanislav, Kappeler, Dominik, Buhl, Roland, Beeh, Kai-Michael, Kornmann, Oliver, Kirsten, Anne, Homburg, Ursula, Garn, Holger, Krug, Norbert, Hohlfeld, Jens Michael
Introduction: The analysis of cytokines and mediators in sputum supernatants may be affected by endogenous proteases and the processing of sputum with dithiothreitol (DTT) during homogenization. Sputum extraction with PBS (Respiration 2012), dialysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______610::ee5a0631fad5af17c74c99e516bed405
https://publica.fraunhofer.de/handle/publica/238518
https://publica.fraunhofer.de/handle/publica/238518
Autor:
Holz, Olaf, Biller, Heike, Müller, Meike, Kane, Katie, Rosano, Molly, Hanrahan, John, Hava, David L., Hohlfeld, Jens Michael
INTRODUCTION: The ozone challenge model can be used to assess the efficacy of novel anti-inflammatory compounds early during drug development. In this study we evaluated the efficacy of PUR118 in attenuating ozone-induced airway inflammation in healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______610::49799f7f2718e4ae70e7658fddf55542
https://publica.fraunhofer.de/handle/publica/238095
https://publica.fraunhofer.de/handle/publica/238095