Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hogue Christopher WV"'
Publikováno v:
BMC Bioinformatics, Vol 12, Iss Suppl 13, p S13 (2011)
Abstract Background LRP6 is a membrane protein crucial in the initiation of canonical Wnt/β-catenin signalling. Its function is dependent on its proline-serine rich intracellular domain. LRP6 has five PPP(S/T)P motifs that are phosphorylated during
Externí odkaz:
https://doaj.org/article/f8e0b1b1a9844a8ba2b768c1f77fe6f0
Publikováno v:
BMC Bioinformatics, Vol 7, Iss 1, p 152 (2006)
Abstract Background Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule binding site protein sequence annotation is sparse. The Small Molecu
Externí odkaz:
https://doaj.org/article/270e94a6f5484781977b9972d936545e
Autor:
Baskin Berivan, Zhang Shudong, Tuekam Brigitte, Lay Vicki, Wolting Cheryl, de Bruijn Berry, Martin Joel, Donaldson Ian, Bader Gary D, Michalickova Katerina, Pawson Tony, Hogue Christopher WV
Publikováno v:
BMC Bioinformatics, Vol 4, Iss 1, p 11 (2003)
Abstract Background The majority of experimentally verified molecular interaction and biological pathway data are present in the unstructured text of biomedical journal articles where they are inaccessible to computational methods. The Biomolecular i
Externí odkaz:
https://doaj.org/article/0f22bf78af614665abbefcf57e2eb66f
Autor:
Bader Gary D, Hogue Christopher WV
Publikováno v:
BMC Bioinformatics, Vol 4, Iss 1, p 2 (2003)
Abstract Background Recent advances in proteomics technologies such as two-hybrid, phage display and mass spectrometry have enabled us to create a detailed map of biomolecular interaction networks. Initial mapping efforts have already produced a weal
Externí odkaz:
https://doaj.org/article/b6fa71468da74e97bda89001c7721bb7
Publikováno v:
BMC Bioinformatics, Vol 3, Iss 1, p 39 (2002)
Abstract Background An organism's ability to adapt to its particular environmental niche is of fundamental importance to its survival and proliferation. In the largest study of its kind, we sought to identify and exploit the amino-acid signatures tha
Externí odkaz:
https://doaj.org/article/2f4304ac80f547d8b85dc6e744d1e429
Autor:
Dumontier Michel, Bader Gary D, Michalickova Katerina, Lieu Hao, Betel Doron, Isserlin Ruth, Hogue Christopher WV
Publikováno v:
BMC Bioinformatics, Vol 3, Iss 1, p 32 (2002)
Abstract Background SeqHound has been developed as an integrated biological sequence, taxonomy, annotation and 3-D structure database system. It provides a high-performance server platform for bioinformatics research in a locally-hosted environment.
Externí odkaz:
https://doaj.org/article/b7d8df393be0496d9e5de3d9445e9aeb
Autor:
Betel Doron, Hogue Christopher WV
Publikováno v:
BMC Bioinformatics, Vol 3, Iss 1, p 20 (2002)
Abstract Background Biologists are often interested in performing a simple database search to identify proteins or genes that contain a well-defined sequence pattern. Many databases do not provide straightforward or readily available query tools to p
Externí odkaz:
https://doaj.org/article/11839f81e5f34d22844bcc6cd2b9556d
Autor:
Dumontier Michel, Hogue Christopher WV
Publikováno v:
BMC Bioinformatics, Vol 3, Iss 1, p 13 (2002)
Abstract Background The BLAST algorithm compares biological sequences to one another in order to determine shared motifs and common ancestry. However, the comparison of all non-redundant (NR) sequences against all other NR sequences is a computationa
Externí odkaz:
https://doaj.org/article/5c53e17587fe47628156e7fc57cde04a