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Akademický článek

Painful nerve injury increases plasma membrane Ca2+-ATPase activity in axotomized sensory neurons

Autor: Gemes Geza, Oyster Katherine D, Pan Bin, Wu Hsiang-En, Bangaru Madhavi Latha, Tang Qingbo, Hogan Quinn H

Publikováno v: Molecular Pain, Vol 8, Iss 1, p 46 (2012)

Abstract Background The plasma membrane Ca2+-ATPase (PMCA) is the principal means by which sensory neurons expel Ca2+ and thereby regulate the concentration of cytoplasmic Ca2+ and the processes controlled by this critical second messenger. We have p

Externí odkaz: https://doaj.org/article/7ca35299dbc946f996c71992452230ae

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Akademický článek

Lentiviral gene transfer into the dorsal root ganglion of adult rats

Autor: Park Frank, Reiser Jakob, Jia Guangfu, Fischer Greg, Yu Hongwei, Hogan Quinn H

Publikováno v: Molecular Pain, Vol 7, Iss 1, p 63 (2011)

Abstract Background Lentivector-mediated gene delivery into the dorsal root ganglion (DRG) is a promising method for exploring pain pathophysiology and for genetic treatment of chronic neuropathic pain. In this study, a series of modified lentivector

Externí odkaz: https://doaj.org/article/094de6789782480ab449cd54a6df7a2f

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Akademický článek

KATP channel subunits in rat dorsal root ganglia: alterations by painful axotomy

Autor: Gemes Geza, McCallum Bruce, Weihrauch Dorothee, Bienengraeber Martin, Liang Mei-Ying, Kawano Takashi, Zoga Vasiliki, Hogan Quinn, Sarantopoulos Constantine

Publikováno v: Molecular Pain, Vol 6, Iss 1, p 6 (2010)

Abstract Background ATP-sensitive potassium (KATP) channels in neurons mediate neuroprotection, they regulate membrane excitability, and they control neurotransmitter release. Because loss of DRG neuronal KATP currents is involved in the pathophysiol

Externí odkaz: https://doaj.org/article/a845256b521045b89aa280619c08a517

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Akademický článek

Nitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation

Autor: Kwok Wai-Meng, McCallum J Bruce, Gemes Geza, Wu Hsiang-En, Liang Mei-Ying, Kimura Masakazu, Zoga Vasiliki, Kawano Takashi, Hogan Quinn H, Sarantopoulos Constantine D

Publikováno v: Molecular Pain, Vol 5, Iss 1, p 12 (2009)

Abstract Background ATP-sensitive potassium (KATP) channels in neurons regulate excitability, neurotransmitter release and mediate protection from cell-death. Furthermore, activation of KATP channels is suppressed in DRG neurons after painful-like ne

Externí odkaz: https://doaj.org/article/8b5110ec7c8f4268840cb15df9a736d9

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