Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes.

Autor: Pekayvaz K; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany. kami.pekayvaz@med.uni-muenchen.de.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany. kami.pekayvaz@med.uni-muenchen.de., Losert C; Institute of Computational Biology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany.; Department of Computer Science, TUM School of Computation, Information and Technology, Technical University of Munich, Garching, Germany., Knottenberg V; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany., Gold C; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany., van Blokland IV; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Oelen R; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Groot HE; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Benjamins JW; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Brambs S; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany., Kaiser R; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany., Gottschlich A; Department of Medicine III, LMU University Hospital, Munich, Germany.; Division of Clinical Pharmacology, LMU University Hospital, Member of the German Center for Lung Research (DZL), Munich, Germany., Hoffmann GV; Division of Clinical Pharmacology, LMU University Hospital, Member of the German Center for Lung Research (DZL), Munich, Germany., Eivers L; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany., Martinez-Navarro A; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany., Bruns N; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany., Stiller S; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany., Akgöl S; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany., Yue K; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany., Polewka V; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany., Escaig R; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany., Joppich M; Department of Informatics, Ludwig-Maximilian University, Munich, Germany., Janjic A; Anthropology and Human Genomics, Faculty of Biology, Ludwig-Maximilian University, Munich, Germany., Popp O; Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Kobold S; Division of Clinical Pharmacology, LMU University Hospital, Member of the German Center for Lung Research (DZL), Munich, Germany.; German Cancer Consortium (DKTK), a partnership between DKFZ and LMU University Hospital, Partner Site Munich, Munich, Germany.; Einheit für Klinische Pharmakologie (EKLiP), Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Petzold T; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany.; Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité (DHZC), Berlin, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany.; Charite-Universitätsmedizin Berlin, Berlin, Germany., Zimmer R; Department of Informatics, Ludwig-Maximilian University, Munich, Germany., Enard W; Anthropology and Human Genomics, Faculty of Biology, Ludwig-Maximilian University, Munich, Germany., Saar K; Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany., Mertins P; Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Huebner N; Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany.; Charite-Universitätsmedizin Berlin, Berlin, Germany., van der Harst P; Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands., Franke LH; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., van der Wijst MGP; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Massberg S; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany., Heinig M; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany. matthias.heinig@helmholtz-muenchen.de.; Institute of Computational Biology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany. matthias.heinig@helmholtz-muenchen.de.; Department of Computer Science, TUM School of Computation, Information and Technology, Technical University of Munich, Garching, Germany. matthias.heinig@helmholtz-muenchen.de., Nicolai L; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany. leo.nicolai@med.uni-muenchen.de.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany. leo.nicolai@med.uni-muenchen.de., Stark K; Medizinische Klinik und Poliklinik I, LMU University Hospital, Munich, Germany. konstantin.stark@med.uni-muenchen.de.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany. konstantin.stark@med.uni-muenchen.de.

Publikováno v: Nature medicine [Nat Med] 2024 Jun; Vol. 30 (6), pp. 1696-1710. Date of Electronic Publication: 2024 May 21.