Výsledky vyhledávání - "Hoffman, N. G."

Subtype-Specific Conformational Differences within the V3 Region of Subtype B and Subtype C Human Immunodeficiency Virus Type 1 Env Proteins

Autor: Hoffman, N. G., Patel, M. B., Swanstrom, R.

The V3 region of the human immunodeficiency virus type 1 gp120 Env protein is a key domain in Env due to its role in interacting with the coreceptors CCR5 and CXCR4. We examined potential subtype-specific V3 region differences by comparing patterns o

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Multiple V1/V2 env Variants Are Frequently Present during Primary Infection with Human Immunodeficiency Virus Type 1

Autor: Swanstrom, R., Eron, J. J., Fiscus, S. A., Ritola, K., Hicks, C. B., Kitrinos, K. M., Nelson, J. A. E., Pilcher, C. D., Hoffman, N. G.

Human immunodeficiency virus type 1 (HIV-1) exists as a complex population of multiple genotypic variants in persons with chronic infection. However, acute HIV-1 infection via sexual transmission is a low-probability event in which there is thought t

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Turnover of env Variable Region 1 and 2 Genotypes in Subjects with Late-Stage Human Immunodeficiency Virus Type 1 Infection

Autor: Nelson, J. A. E., Kitrinos, K. M., Swanstrom, R., Hoffman, N. G.

The env gene of human immunodeficiency virus type 1 (HIV-1) includes some of the most genetically diverse regions of the viral genome, which are called variable regions 1 through 5 (V1 through V5). We have developed a heteroduplex tracking assay to d

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Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2

Autor: Fowlkes, D. M., Sparks, A. B., Kay, B. K., Hoffman, N. G., Rider, J. E., Quillam, L. A.

Src homology 3 (SH3) domains are conserved protein modules 50-70 amino acids long found in a variety of proteins with important roles in signal transduction. These domains have been shown to mediate protein-protein interactions by binding short proli

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Periodical

Using HIV-1 sequence variability to explore virus biology

Autor: McGrath, K. M., Hoffman, N. G., Resch, W., Nelson, J. A., Swanstrom, R.

Publikováno v: Virus Research; 2001, Vol. 76 Issue: 2 p137-160, 24p

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Periodical

Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.

Autor: Sparks, A B, Rider, J E, Hoffman, N G, Fowlkes, D M, Quillam, L A, Kay, B K

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; February 1996, Vol. 93 Issue: 4 p1540-1544, 5p

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Periodical

A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes.

Autor: Ribon, V, Printen, J A, Hoffman, N G, Kay, B K, Saltiel, A R

Publikováno v: Molecular and Cellular Biology; February 1998, Vol. 18 Issue: 2 p872-9, 8p

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Periodical

Intersectin, a novel adaptor protein with two Eps15 homology and five Src homology 3 domains.

Autor: Yamabhai, M, Hoffman, N G, Hardison, N L, McPherson, P S, Castagnoli, L, Cesareni, G, Kay, B K

Publikováno v: Journal of Biological Chemistry; November 1998, Vol. 273 Issue: 47 p31401-7, 7p

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