Blockage of BCL-XL overcomes venetoclax resistance across BCL2+ lymphoid malignancies irrespective of BIM status

Autor: Dolnikova, Alexandra, Kazantsev, Dmitry, Klanova, Magdalena, Pokorna, Eva, Sovilj, Dana, Kelemen, Cristina Daniela, Tuskova, Liliana, Hoferkova, Eva, Mraz, Marek, Helman, Karel, Curik, Nikola, Machova Polakova, Katerina, Andera, Ladislav, Trneny, Marek, Klener, Pavel

Publikováno v: In Blood Advances 9 July 2024 8(13):3532-3543

In Vitro and In Vivo Models of CLL–T Cell Interactions: Implications for Drug Testing.

Autor: Hoferkova, Eva^1,2,3 (AUTHOR), Kadakova, Sona¹ (AUTHOR), Mraz, Marek^1,2 (AUTHOR) marek.mraz@email.cz

Publikováno v: Cancers. Jul2022, Vol. 14 Issue 13, pN.PAG-N.PAG. 21p.

Blockage of BCL-XL overcomes venetoclax resistance across BCL2+lymphoid malignancies irrespective of BIM status

Autor: Dolnikova, Alexandra, Kazantsev, Dmitry, Klanova, Magdalena, Pokorna, Eva, Sovilj, Dana, Kelemen, Cristina D., Tuskova, Liliana, Hoferkova, Eva, Mraz, Marek, Helman, Karel, Curik, Nikola, Machova Polakova, Katerina, Andera, Ladislav, Trneny, Marek, Klener, Pavel

Publikováno v: Blood Advances; 20240101, Issue: Preprints

FoxO1/Rictor axis induces a non-genetic adaptation to Ibrutinib via Akt activation in chronic lymphocytic leukemia.

Autor: Ondrisova L; Molecular Medicine, CEITEC Masaryk University, Brno, Czech Republic., Seda V; Molecular Medicine, CEITEC Masaryk University, Brno, Czech Republic., Hlavac K; Molecular Medicine, CEITEC Masaryk University, Brno, Czech Republic., Pavelkova P; Molecular Medicine, CEITEC Masaryk University, Brno, Czech Republic., Hoferkova E; Molecular Medicine, CEITEC Masaryk University, Brno, Czech Republic., Chiodin G; Cancer Sciences Unit, University of Southampton, Southampton, United Kingdom., Kostalova L; Molecular Medicine, CEITEC Masaryk University, Brno, Czech Republic., Mladonicka Pavlasova G; Molecular Medicine, CEITEC Masaryk University, Brno, Czech Republic., Filip D; Molecular Medicine, CEITEC Masaryk University, Brno, Czech Republic., Vecera J; Molecular Medicine, CEITEC Masaryk University, Brno, Czech Republic., Zeni PF; Molecular Medicine, CEITEC Masaryk University, Brno, Czech Republic., Oppelt J; Molecular Medicine, CEITEC Masaryk University, Brno, Czech Republic., Kahounova Z; Department of Cytokinetics, Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic., Vichova R; Department of Cytokinetics, Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic., Soucek K; Department of Cytokinetics, Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic., Panovska A; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic., Plevova K; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic., Pospisilova S; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic., Simkovic M; 4th Department of Internal Medicine - Haematology, University Hospital Hradec Kralove and Faculty of Medicine Hradec Kralove, Charles University, Prague, Czech Republic., Vrbacky F; 4th Department of Internal Medicine - Haematology, University Hospital Hradec Kralove and Faculty of Medicine Hradec Kralove, Charles University, Prague, Czech Republic., Lysak D; Department of Haematology and Oncology, University Hospital Pilsen, Pilsen, Czech Republic., Fernandes SM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America., Davids MS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America., Maiques-Diaz A; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain., Charalampopoulou S; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain., Martin-Subero JI; Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain., Brown JR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States of America., Doubek M; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic., Forconi F; Cancer Science Unit, University of Southampton, Southampton, United Kingdom., Mayer J; Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic., Mraz M; Molecular Medicine, CEITEC Masaryk University, Brno, Czech Republic.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2024 Oct 22. Date of Electronic Publication: 2024 Oct 22.