Zobrazeno 1 - 10
of 472
pro vyhledávání: '"Hofacker, Ivo L."'
Autor:
Berkemer, Sarah J., Höner zu Siederdissen, Christian, Amman, Fabian, Wintsche, Axel, Will, Sebastian, Hofacker, Ivo L., Prohaska, Sonja J., Stadler, Peter F.
Publikováno v:
Genomics and computational biology Vol. 1, No. 1 (2015): e18
Bulge-helix-bulge (BHB) elements guide the enzymatic splicing machinery that in Archaea excises introns from tRNAs, rRNAs from their primary precursor, and accounts for the assembly of piece-wise encoded tRNAs. This processing pathway renders the int
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A13790
https://ul.qucosa.de/api/qucosa%3A13790/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A13790/attachment/ATT-0/
Translational Control by RNA-RNA Interaction: Improved Computation of RNA-RNA Binding Thermodynamics
Autor:
Mückstein, Ulrike, Tafer, Hakim, Bernhart, Stephan H., Hernandez-Rosales, Maribel, Vogel, Jörg, Stadler, Peter F., Hofacker, Ivo L.
The thermodynamics of RNA-RNA interaction consists of two components: the energy necessary to make a potential binding region accessible, i.e., unpaired, and the energy gained from the base pairing of the two interaction partners. We show here that b
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A32007
https://ul.qucosa.de/api/qucosa%3A32007/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A32007/attachment/ATT-0/
The increasing complexity of models for prediction of the native spatial structure of RNA molecules requires visualization methods that help to analyze and understand the models and their predictions. This paper improves the visualization method for
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A32935
https://ul.qucosa.de/api/qucosa%3A32935/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A32935/attachment/ATT-0/
Barrier trees are a convenient way of representing the structure of complex combinatorial landscapes over graphs. Here we generalize the concept of barrier trees to landscapes defined over general multi-parent search operators based on a suitable not
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A32606
https://ul.qucosa.de/api/qucosa%3A32606/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A32606/attachment/ATT-0/
The analysis of small circular sequences requires specialized tools. While the differences between linear and circular sequences can be neglected in the case of long molecules such as bacterial genomes since in practice all analysis is performed in s
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A32019
https://ul.qucosa.de/api/qucosa%3A32019/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A32019/attachment/ATT-0/
Autor:
Hofacker, Ivo L., Stadler, Peter F.
In recent years it has become evident that functional RNAs in living organisms are not just curious remnants from a primoridal RNA world but an ubiquitous phenomenon complementing protein enzyme based activity. Functional RNAs, just like proteins, de
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A32981
https://ul.qucosa.de/api/qucosa%3A32981/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A32981/attachment/ATT-0/
Pseudoknots are essential for the functioning of many small RNA molecules. In addition, viral RNAs often exhibit pseudoknots that are required at various stages of the viral life-cycle. Techniques for detecting evolutionarily conserved, and hence mos
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A31909
https://ul.qucosa.de/api/qucosa%3A31909/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31909/attachment/ATT-0/
Autor:
Hofacker, Ivo L., Stadler, Peter F.
Many classes of functional RNA molcules are characterized by highly conserved secondary structures but little detectable sequence similarity. Reliable multiple alignments can therefore be constructed only when the shared structural features are taken
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A32982
https://ul.qucosa.de/api/qucosa%3A32982/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A32982/attachment/ATT-0/
Autor:
Gruber, Andreas R., Kilgus, Carsten, Mosig, Axel, Hofacker, Ivo L., Hennig, Wolfgang, Stadler, Peter F.
The 7SK small nuclear RNA (snRNA) is a key player in the regulation of polymerase (pol) II transcription. The 7SK RNA was long believed to be specific to vertebrates where it is highly conserved. Homologs in basal deuterostomes and a few lophotrochoz
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A32793
https://ul.qucosa.de/api/qucosa%3A32793/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A32793/attachment/ATT-0/
Autor:
Gruber, Andreas R., Koper-Emde, Dorota, Marz, Manja, Tafer, Hakim, Bernhart, Stephan, Obernosterer, Gregor, Mosig, Axel, Hofacker, Ivo L., Stadler, Peter F., Benecke, Bernd-Joachim
7SK RNA is a highly abundant noncoding RNA in mammalian cells whose function in transcriptional regulation has only recently been elucidated. Despite its highly conserved sequence throughout vertebrates, all attempts to discover 7SK RNA homologues in
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A32794
https://ul.qucosa.de/api/qucosa%3A32794/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A32794/attachment/ATT-0/