Biophysical and Biochemical Characterization of Structurally Diverse Small Molecule Hits for KRAS Inhibition.

Autor: Pagba CV; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin St., Houston, Texas, 77030, USA., Gupta AK; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin St., Houston, Texas, 77030, USA., Dilsha K; Department of Chemistry, University of Houston, 3585 Cullen Blvd., Houston, TX 77204, USA., Sadrpour P; Department of Biochemistry and Molecular Biology, Wright State University, 3640 Colonel Glenn Hwy, Dayton, OH 45435, USA., Jakubec J; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin St., Houston, Texas, 77030, USA., Prakash P; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin St., Houston, Texas, 77030, USA., van der Hoeven D; Department of Diagnostic and Biomedical Sciences, School of Dentistry, The University of Texas Health Science Center at Houston, 7500 Cambridge St., Houston, Texas, 77030, USA., Cho KJ; Department of Biochemistry and Molecular Biology, Wright State University, 3640 Colonel Glenn Hwy, Dayton, OH 45435, USA., Gilbertson S; Department of Chemistry, University of Houston, 3585 Cullen Blvd., Houston, TX 77204, USA., Gorfe AA; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin St., Houston, Texas, 77030, USA.; Biochemistry and Cell Biology Program & Therapeutics and Pharmacology Program, UTHealth MD Anderson Cancer Center Graduate School of Biomedical Sciences, Houston, 6431 Fannin St., Houston, Texas, 77030, USA.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Apr 02; Vol. 25 (7), pp. e202300827. Date of Electronic Publication: 2024 Mar 07.

A Near-Optimal Best-of-Both-Worlds Algorithm for Online Learning with Feedback Graphs

Autor: Rouyer, C., van der Hoeven, D., Cesa Bianchi, N., Seldin, Y.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1261::1e31e87f9f6a414e91347c1b74a367ef
https://hdl.handle.net/2434/961296

The impact of coronavirus disease 2019 pandemic on dental school assessments - Current status and future perspectives.

Autor: Parikh N; Department of Diagnostic and Biomedical Sciences, School of Dentistry, The University of Texas Health Science Center at Houston, Houston, USA., Gardner A; Department of General Practice and Dental Public Health, School of Dentistry, The University of Texas Health Science Center at Houston, Houston, USA., Myers AL; Department of Diagnostic and Biomedical Sciences, School of Dentistry, The University of Texas Health Science Center at Houston, Houston, USA., Halpin R; School of Dentistry, The University of Texas Health Science Center at Houston, Houston, USA., Holland JN; School of Dentistry, The University of Texas Health Science Center at Houston, Houston, USA., van der Hoeven D; Department of Diagnostic and Biomedical Sciences, School of Dentistry, The University of Texas Health Science Center at Houston, Houston, USA.

Publikováno v: Journal of dental education [J Dent Educ] 2023 Jun; Vol. 87 (6), pp. 825-842. Date of Electronic Publication: 2023 Feb 28.

MetaGrad: Adaptation using Multiple Learning Rates in Online Learning

Autor: Tim van Erven, Koolen, W. M., Hoeven, D.

Publikováno v: Scopus-Elsevier
Journal of Machine Learning Research, 22, 1-61

We provide a new adaptive method for online convex optimization, MetaGrad, that is ro- bust to general convex losses but achieves faster rates for a broad class of special functions, including exp-concave and strongly convex functions, but also vario

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75003f071aa085e9c7a190035fbe1eea

KRAS Inhibitor that Simultaneously Inhibits Nucleotide Exchange Activity and Effector Engagement.

Autor: Pagba CV; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, Texas 77030, United States., Gupta AK; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, Texas 77030, United States., Naji AK; Department of Diagnostic and Biomedical Sciences, School of Dentistry, The University of Texas Health Science Center at Houston, 7500 Cambridge Street, Houston, Texas 77030, United States., van der Hoeven D; Department of Diagnostic and Biomedical Sciences, School of Dentistry, The University of Texas Health Science Center at Houston, 7500 Cambridge Street, Houston, Texas 77030, United States., Churion K; Center for Infectious and Inflammatory Diseases, Texas A&M University Health Science Center, 2121 W Holcombe Blvd, Houston, Texas 77030, United States., Liang X; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, Texas 77030, United States., Jakubec J; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, Texas 77030, United States., Hook M; Center for Infectious and Inflammatory Diseases, Texas A&M University Health Science Center, 2121 W Holcombe Blvd, Houston, Texas 77030, United States., Zuo Y; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, Texas 77030, United States., Martinez de Kraatz M; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, Texas 77030, United States., Frost JA; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, Texas 77030, United States.; Biochemistry and Cell Biology Program, UTHealth MD Anderson Cancer Center Graduate School of Biomedical Sciences, 6431 Fannin Street, Houston, Texas 77030, United States., Gorfe AA; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, Texas 77030, United States.; Biochemistry and Cell Biology Program & Therapeutics and Pharmacology Program, UTHealth MD Anderson Cancer Center Graduate School of Biomedical Sciences, 6431 Fannin Street, Houston, Texas 77030, United States.

Publikováno v: ACS bio & med chem Au [ACS Bio Med Chem Au] 2022 Sep 26; Vol. 2 (6), pp. 617-626. Date of Electronic Publication: 2022 Sep 26 (Print Publication: 2022).