Presynaptic inhibition upon CB1 or mGlu2/3 receptor activation requires ERK/MAPK phosphorylation of Munc18‐1

Autor: Schmitz, Sabine K, King, Cillian, Kortleven, Christian, Huson, Vincent, Kroon, Tim, Kevenaar, Josta T, Schut, Desiree, Saarloos, Ingrid, Hoetjes, Joost P, de Wit, Heidi, Stiedl, Oliver, Spijker, Sabine, Li, Ka Wan, Mansvelder, Huibert D, Smit, August B, Cornelisse, Lennart Niels, Verhage, Matthijs, Toonen, Ruud F

Publikováno v: EMBO Journal, 35(11), 1236-50. Wiley-Blackwell
Schmitz, S K, King, C, Kortleven, C, Huson, V, Kroon, T, Kevenaar, J T, Schut, D, Saarloos, I, Hoetjes, J P, de Wit, H, Stiedl, O, Spijker, S, Li, K W, Mansvelder, H D, Smit, A B, Cornelisse, L N, Verhage, M & Toonen, R F 2016, ' Presynaptic inhibition upon CB1 or mGlu2/3 receptor activation requires ERK/MAPK phosphorylation of Munc18-1 ', EMBO Journal, vol. 35, no. 11, pp. 1236-50 . https://doi.org/10.15252/embj.201592244

Presynaptic cannabinoid (CB1R) and metabotropic glutamate receptors (mGluR2/3) regulate synaptic strength by inhibiting secretion. Here, we reveal a presynaptic inhibitory pathway activated by extracellular signal-regulated kinase (ERK) that mediates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::59608385332958e1cca14699c64aeff0
https://europepmc.org/articles/PMC4888233/