Pharmacological characterization of a novel positive modulator at α 4β 3δ-containing extrasynaptic GABA A receptors

Autor: Hoestgaard-Jensen, K., Dalby, N.O., Wolinsky, T.D., Murphey, C., Jones, K.A., Rottländer, M., Frederiksen, K., Watson, W.P., Jensen, K., Ebert, B.

Publikováno v: In Neuropharmacology 2010 58(4):702-711

Synthesis, In Vivo Anticonvulsant Activity Evaluation and In Silico Studies of Some Quinazolin-4(3H)-One Derivatives.

Autor: Pele, Raluca¹ (AUTHOR) raluca.pele@umfcluj.ro, Marc, Gabriel¹ (AUTHOR) marc.gabriel@umfcluj.ro, Mogoșan, Cristina² (AUTHOR) anamaria.cristina@umfcluj.ro, Apan, Anamaria² (AUTHOR), Ionuț, Ioana¹ (AUTHOR) ionut.ioana@umfcluj.ro, Tiperciuc, Brîndușa¹ (AUTHOR) btiperciuc@umfcluj.ro, Moldovan, Cristina¹ (AUTHOR) cmoldovan@umfcluj.ro, Araniciu, Cătălin³ (AUTHOR) araniciu.catalin@umfcluj.ro, Oniga, Ilioara⁴ (AUTHOR) ioniga@umfcluj.ro, Pîrnău, Adrian⁵ (AUTHOR) adrian.pirnau@itim-cj.ro, Vlase, Laurian⁶ (AUTHOR) laurian.vlase@umfcluj.ro, Oniga, Ovidiu¹ (AUTHOR) ooniga@umfcluj.ro

Publikováno v: Molecules. May2024, Vol. 29 Issue 9, p1951. 24p.

Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism.

Autor: Chua HC; Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia., Christensen ET; Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia.; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hoestgaard-Jensen K; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hartiadi LY; Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia., Ramzan I; Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia., Jensen AA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Absalom NL; Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia., Chebib M; Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia.

Publikováno v: PloS one [PLoS One] 2016 Jun 22; Vol. 11 (6), pp. e0157700. Date of Electronic Publication: 2016 Jun 22 (Print Publication: 2016).

A Multifaceted GABAA Receptor Modulator: Functional Properties and Mechanism of Action of the Sedative-Hypnotic and Recreational Drug Methaqualone (Quaalude).

Autor: Hammer H; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (H.H., L.B., K.H.-J., A.A.J.); NeuroProof, Rostock, Germany (B.M.B., C.E., O.H.-U.S., A.G.-V.); and H. Lundbeck A/S, Valby, Denmark (C.B., J.F.B.)., Bader BM; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (H.H., L.B., K.H.-J., A.A.J.); NeuroProof, Rostock, Germany (B.M.B., C.E., O.H.-U.S., A.G.-V.); and H. Lundbeck A/S, Valby, Denmark (C.B., J.F.B.)., Ehnert C; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (H.H., L.B., K.H.-J., A.A.J.); NeuroProof, Rostock, Germany (B.M.B., C.E., O.H.-U.S., A.G.-V.); and H. Lundbeck A/S, Valby, Denmark (C.B., J.F.B.)., Bundgaard C; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (H.H., L.B., K.H.-J., A.A.J.); NeuroProof, Rostock, Germany (B.M.B., C.E., O.H.-U.S., A.G.-V.); and H. Lundbeck A/S, Valby, Denmark (C.B., J.F.B.)., Bunch L; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (H.H., L.B., K.H.-J., A.A.J.); NeuroProof, Rostock, Germany (B.M.B., C.E., O.H.-U.S., A.G.-V.); and H. Lundbeck A/S, Valby, Denmark (C.B., J.F.B.)., Hoestgaard-Jensen K; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (H.H., L.B., K.H.-J., A.A.J.); NeuroProof, Rostock, Germany (B.M.B., C.E., O.H.-U.S., A.G.-V.); and H. Lundbeck A/S, Valby, Denmark (C.B., J.F.B.)., Schroeder OH; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (H.H., L.B., K.H.-J., A.A.J.); NeuroProof, Rostock, Germany (B.M.B., C.E., O.H.-U.S., A.G.-V.); and H. Lundbeck A/S, Valby, Denmark (C.B., J.F.B.)., Bastlund JF; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (H.H., L.B., K.H.-J., A.A.J.); NeuroProof, Rostock, Germany (B.M.B., C.E., O.H.-U.S., A.G.-V.); and H. Lundbeck A/S, Valby, Denmark (C.B., J.F.B.)., Gramowski-Voß A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (H.H., L.B., K.H.-J., A.A.J.); NeuroProof, Rostock, Germany (B.M.B., C.E., O.H.-U.S., A.G.-V.); and H. Lundbeck A/S, Valby, Denmark (C.B., J.F.B.)., Jensen AA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (H.H., L.B., K.H.-J., A.A.J.); NeuroProof, Rostock, Germany (B.M.B., C.E., O.H.-U.S., A.G.-V.); and H. Lundbeck A/S, Valby, Denmark (C.B., J.F.B.) aaj@sund.ku.dk.

Publikováno v: Molecular pharmacology [Mol Pharmacol] 2015 Aug; Vol. 88 (2), pp. 401-20. Date of Electronic Publication: 2015 Jun 08.

Progress in GABAA receptor agonists for insomnia disorder.

Autor: Wang, Weiyi, Fu, Wanting, Zhu, Hongyan, Ma, Jing, Zhang, Jian, Qi, Jia

Publikováno v: Frontiers in Pharmacology; 2024, p1-9, 9p