Underlying Neural Mechanisms of Cognitive Improvement in Fronto-striatal Response Inhibition in People Living with HIV Switching Off Efavirenz: A Randomized Controlled BOLD fMRI Trial

Autor: Patrick G. A. Oomen, Charlotte S. Hakkers, Joop E. Arends, Guido E. L. van der Berk, Pascal Pas, Andy I. M. Hoepelman, Berend J. van Welzen, Stefan du Plessis

Publikováno v: Infectious Diseases and Therapy, Vol 13, Iss 5, Pp 1067-1082 (2024)

Abstract Introduction It is unclear whether neurotoxicity due to the antiretroviral drug efavirenz (EFV) results in neurocognitive impairment in people living with HIV (PLWH). Previously, we found that discontinuing EFV was associated with improved p

Externí odkaz: https://doaj.org/article/89b5bb64f5f64621904886fd09fc1739

Let’s Agree to Disagree on Operative Versus Nonoperative Treatment for Distal Radius Fractures in Older People: Protocol for a Prospective International Multicenter Cohort Study

Autor: Nicole Maria van Veelen, Bryan J M van de Wall, Ruben J Hoepelman, Frank F A IJpma, Björn-Christian Link, Reto Babst, Rolf H H Groenwold, Detlef van der Velde, Nadine Diwersi, Mark van Heijl, R Marijn Houwert, Frank J P Beeres

Publikováno v: JMIR Research Protocols, Vol 13, p e52917 (2024)

BackgroundDistal radius fractures are the most frequently encountered fractures in Western societies, typically affecting patients aged 50 years and older. Although this is a common injury, the best treatment for these fractures in older patients is

Externí odkaz: https://doaj.org/article/ce83f92f1aa246b98678faa1e07e8a40

Tracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach

Autor: Perrin Luc, Ormaasen Vidar, Op de Coul Eline LM, Meyer Laurence, Nielsen Claus, Maljkovic-Berry I, MacRae Eilidh, Loveday Clive, Leitner Thomas, Korn Klaus, Kücherer Claudia, Horban Andrzej, Hoepelman IM, Hamouda Osama, Grossman Zehava, de Mendoza Carmen, Derdelinckx Inge, De Luca Andrea, Costagliola Dominique, Coughlan Suzie, Chaix Marie-Laure, Camacho Ricardo, Boeri Enzo, Balotta Claudia, Åsjö Birgitta, Angarano Guiseppe, Albert Jan, van de Vijver David A, Wensing Annemarie MJ, Hatzakis Angelos, Magiorkinis Gkikas, Pybus Oliver, Paraskevis Dimitrios, Puchhammer-Stöckl Elisabeth, Ruiz Lidia, Salminen Mika O, Schmit Jean-Claude, Schuurman Rob, Soriano Vincent, Stanczak J, Stanojevic Maja, Struck Daniel, Van Laethem Kristel, Violin M, Yerly Sabine, Zazzi Maurizio, Boucher Charles A, Vandamme Anne-Mieke

Publikováno v: Retrovirology, Vol 6, Iss 1, p 49 (2009)

Abstract Background The prevalence and the origin of HIV-1 subtype B, the most prevalent circulating clade among the long-term residents in Europe, have been studied extensively. However the spatial diffusion of the epidemic from the perspective of t

Externí odkaz: https://doaj.org/article/26829cc1663d44378614196b8bef0042

Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials

Autor: Cathrine Axfors, Andreas M. Schmitt, Perrine Janiaud, Janneke van’t Hooft, Sherief Abd-Elsalam, Ehab F. Abdo, Benjamin S. Abella, Javed Akram, Ravi K. Amaravadi, Derek C. Angus, Yaseen M. Arabi, Shehnoor Azhar, Lindsey R. Baden, Arthur W. Baker, Leila Belkhir, Thomas Benfield, Marvin A. H. Berrevoets, Cheng-Pin Chen, Tsung-Chia Chen, Shu-Hsing Cheng, Chien-Yu Cheng, Wei-Sheng Chung, Yehuda Z. Cohen, Lisa N. Cowan, Olav Dalgard, Fernando F. de Almeida e Val, Marcus V. G. de Lacerda, Gisely C. de Melo, Lennie Derde, Vincent Dubee, Anissa Elfakir, Anthony C. Gordon, Carmen M. Hernandez-Cardenas, Thomas Hills, Andy I. M. Hoepelman, Yi-Wen Huang, Bruno Igau, Ronghua Jin, Felipe Jurado-Camacho, Khalid S. Khan, Peter G. Kremsner, Benno Kreuels, Cheng-Yu Kuo, Thuy Le, Yi-Chun Lin, Wu-Pu Lin, Tse-Hung Lin, Magnus Nakrem Lyngbakken, Colin McArthur, Bryan J. McVerry, Patricia Meza-Meneses, Wuelton M. Monteiro, Susan C. Morpeth, Ahmad Mourad, Mark J. Mulligan, Srinivas Murthy, Susanna Naggie, Shanti Narayanasamy, Alistair Nichol, Lewis A. Novack, Sean M. O’Brien, Nwora Lance Okeke, Léna Perez, Rogelio Perez-Padilla, Laurent Perrin, Arantxa Remigio-Luna, Norma E. Rivera-Martinez, Frank W. Rockhold, Sebastian Rodriguez-Llamazares, Robert Rolfe, Rossana Rosa, Helge Røsjø, Vanderson S. Sampaio, Todd B. Seto, Muhammad Shahzad, Shaimaa Soliman, Jason E. Stout, Ireri Thirion-Romero, Andrea B. Troxel, Ting-Yu Tseng, Nicholas A. Turner, Robert J. Ulrich, Stephen R. Walsh, Steve A. Webb, Jesper M. Weehuizen, Maria Velinova, Hon-Lai Wong, Rebekah Wrenn, Fernando G. Zampieri, Wu Zhong, David Moher, Steven N. Goodman, John P. A. Ioannidis, Lars G. Hemkens

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-2 (2024)

Externí odkaz: https://doaj.org/article/eaaad84f79e74e2bbfb5c0c8a4146fc5

Dynamics of Low-Level Viremia and Immune Activation after Switching to a Darunavir-Based Regimen

Autor: Arjen J. Stam, Ninée V. E. J. Buchholtz, Wouter F. W. Bierman, Reinout van Crevel, Andy I. M. Hoepelman, Mark A. A. Claassen, Heidi S. M. Ammerlaan, Berend J. van Welzen, Marjo E. E. van Kasteren, Steven F. L. van Lelyveld, Dorien de Jong, Kiki Tesselaar, Matthijs van Luin, Monique Nijhuis, Annemarie M. J. Wensing, LOWERIT Study Team

Publikováno v: Viruses, Vol 16, Iss 2, p 182 (2024)

There is an ongoing debate regarding whether low-level viremia (LLV), in particular persistent LLV, during HIV treatment with optimal adherence originates from low-level viral replication, viral production, or both. We performed an observational stud

Externí odkaz: https://doaj.org/article/f26c5e2ea53642dd922ae0760c7e8299